1. Articles from Diana V. Do

    1-11 of 11
    1. Diurnal variation of choriocapillaris vessel flow density in normal subjects measured using optical coherence tomography angiography

      Diurnal variation of choriocapillaris vessel flow density in normal subjects measured using optical coherence tomography angiography

      Background Vessel flow density (VFD) may provide important information regarding perfusion status. Diurnal variation in VFD of choriocapillaris has not been reported in literature. In the index study, optical coherence tomography angiography (OCTA) was used to assess the diurnal variation of the VFD in the choriocapillaris of subjects with no known ocular disease. Methods Fifty eyes with no known ocular disease (25 subjects) were included. OCTA images were acquired using AngioVue (Optovue, Fremont, CA, USA) at two different time points on a single day: 9:00 AM and 6:00 PM. Macular cube scan protocol (3 × 3 mm) centered on ...

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    2. Evaluation of macular and peripapillary vessel flow density in eyes with no known pathology using optical coherence tomography angiography

      Evaluation of macular and peripapillary vessel flow density in eyes with no known pathology using optical coherence tomography angiography

      Purpose To assess normal vessel flow density (VFD) in macular and peripapillary regions of eyes with no known ocular pathology using optical coherence tomography angiography (OCTA). Methods AngioVue (Optovue, Fremont, CA, USA) was used to capture OCTA images. A 3 × 3 mm grid and a 4.5 × 4.5 mm grid was used to scan parafoveal and peripapillary regions, respectively. ReVue software was utilized to measure VFD in five sectors within the inner two circles of ETDRS grid in macular region and correlated to retinal thickness of same sectors. At optic disc, VFD was calculated in six sectors based on ...

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    3. SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY EVALUATION OF RETINAL STRUCTURE IN PATIENTS WITH SUSACS SYNDROME

      SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY EVALUATION OF RETINAL STRUCTURE IN PATIENTS WITH SUSACS SYNDROME

      Purpose: To report spectral-domain optical coherence tomography (SD-OCT) features in patients diagnosed with Susacs syndrome. Methods: Clinical report of two cases. Results: Spectral-domain optical coherence tomography was performed in two patients diagnosed with Susacs syndrome. Both the patients had normal macular perfusion on fluorescein angiography (FA). However, SD-OCT revealed bilateral, temporal macular atrophy with disorganization and thinning of the retinal layers. The outer plexiform layer showed nodularity and waviness suggestive of ischemic swelling of the bipolar cells. Conclusion: Retinal structural changes in Susacs syndrome have not been described earlier. Spectral-domain optical coherence tomography may be more sensitive than fluorescein angiography ...

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      Mentions: Quan Dong Nguyen
    4. Longitudinal spectral domain optical coherence tomography changes in eyes with intraocular lymphoma

      Longitudinal spectral domain optical coherence tomography changes in eyes with intraocular lymphoma

      Background Cases of patients with primary intraocular lymphoma (PIOL) were retrospectively analyzed to describe the longitudinal intra-retinal morphological changes in PIOL as visualized on images obtained by spectral domain optical coherence tomography (SD-OCT). Results In a retrospective case series, Heidelberg Spectralis SD-OCT images obtained in the longitudinal evaluation of patients with biopsy-proven PIOL were analyzed and assessed. The images were graded for the presence of macular edema (ME), pigment epithelial detachment (PED), subretinal fluid (SRF), and hyperreflective signals. SD-OCT scans of five eyes from five patients were assessed. Patients showed signs of inflammation, such as ME and SRF, which were ...

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    5. Comparison of Time Domain and Spectral Domain Optical Coherence Tomography in Measurement of Macular Thickness in Macular Edema Secondary to Diabetic Retinopathy and Retinal Vein Occlusion

      Comparison of Time Domain and Spectral Domain Optical Coherence Tomography in Measurement of Macular Thickness in Macular Edema Secondary to Diabetic Retinopathy and Retinal Vein Occlusion

      Purpose. To evaluate macular thickness, agreement, and intraclass repeatability in three optical coherence tomography (OCT) devices: the time domain (TD) Stratus OCT and two spectral domain (SD) OCTs, Spectralis and Cirrus SD-OCT, in eyes with macular edema secondary to diabetic retinopathy (DR) and retinal vein occlusion (VO). Methods. In a prospective observational study at a university-based retina practice, retinal thickness tomography was performed simultaneously for fifty-eight patients (91 eyes) with DR and VO employing a time domain and two spectral domain OCTs. Agreement in macular measurements was assessed by constructing Bland-Altman plots. Intraclass repeatability was assessed by intraclass correlation coefficients ...

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    6. Sclerochoroidal Calcifications Imaged Using Enhanced Depth Imaging Optical Coherence Tomography

      Sclerochoroidal Calcifications Imaged Using Enhanced Depth Imaging Optical Coherence Tomography

      Purpose: To report a case of sclerochoroidal calcifications and describe the appearance of these lesions using optical coherence tomography with enhanced depth imaging (EDI-OCT) technology. Design: Case Report Methods: An 85-year-old patient who presented with bilateral retinal lesions suspected to be metastases was evaluated with slit-lamp biomicroscopy, funduscopy, fluorescein angiography, B-scan ultrasonography (U/S), and EDI-OCT. Results: B-scan U/S demonstrated echo-dense consolidations in the choroid bilaterally with acoustic shadowing consistent with sclerochoroidal calcifications. EDI-OCT revealed hyper-reflective lesions with decreased reflectivity posterior to the lesion. Conclusions: Sclerochoroidal calcifications should be included in the differential of choroidal masses, given their unique ...

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    7. Retinal optical coherence tomography manifestations of intraocular lymphoma

      Retinal optical coherence tomography manifestations of intraocular lymphoma

      Purpose Primary central nervous system lymphoma (PCNSL) is a rare disease. The index report describes a patient with intraocular lymphoma secondary to recurrent PCNSL and corresponding retinal findings on spectral domain optical coherence tomography (SD-OCT). Methods Case report. Results OCT changes were documented and correlated with the clinical course of intraocular lymphoma progression in the index patient. The OCT changes, manifested as hyperreflective material accumulation in the intraretinal and subretinal pigment epithelial spaces, were caused by lymphomatous infiltration. Conclusion SD-OCT can be useful in diagnosing and monitoring the progression or regression of intraocular lymphoma with retinal involvement.

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    8. Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study

      Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study

      Purpose To determine the sensitivity of time domain optical coherence tomography (OCT) in detecting conversion to neovascular age-related macular degeneration (AMD) in eyes at high risk for choroidal neovascularization (CNV), compared with detection using fluorescein angiography (FA) as the gold standard. Design Prospective, multicenter, observational study. Participants Individuals aged ≥50 years with nonneovascular AMD at high risk of progressing to CNV in the study eye and evidence of neovascular AMD in the fellow eye. Methods At study entry and every 3 months through 2 years, participants underwent best-corrected visual acuity, supervised Amsler grid testing, preferential hyperacuity perimetry (PHP) testing, stereoscopic ...

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    9. Characterization of macular lesions in punctate inner choroidopathy with spectral domain optical coherence tomography

      Characterization of macular lesions in punctate inner choroidopathy with spectral domain optical coherence tomography

      Abstract Purpose  Punctate inner choroidopathy (PIC) is an ocular inflammatory disease. Spectral domain optical coherence tomography (SD-OCT) allows detailed visualization of retinal and choroidal structures. We aimed to describe the retinal changes on SD-OCT associated with PIC lesions localized in the macula. Methods  Retrospective case series: PIC lesions not associated with choroidal neovascularization (CNV) and captured by macular SD-OCT scans were identified and characterized. Results  Twenty-seven PIC lesions from seven patients (eight eyes) were identified and classified into four categories according to disease activity and temporal changes. Among clinically inactive patients, two main patterns were noted on OCT: (1) retinal ...

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    10. Progressive changes from idiopathic macular telangiectasia seen with spectral domain optical coherence tomography

      Progressive changes from idiopathic macular telangiectasia seen with spectral domain optical coherence tomography

      Idiopathic macular telangiectasia causes bilateral gradual vision loss, usually with an onset between 40 and 60 years of age. Diagnosis is made by clinical examination and fluorescein angiography (FA), which demonstrates late frame leakage from incompetent retinal vessels temporal to the fovea. In addition, parafoveal pigmentary changes are visible, particularly temporal to the fovea, and optical coherence tomography (OCT) often demonstrates hyporeflective spaces within the retina.

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    11. Retinal Thickness Analysis by Race, Gender, and Age Using Stratus OCT

      Purpose: To detect differences in retinal thickness among patients of different race, gender, and age using Stratus OCT.Design: Cross-sectional study.Methods: In a multicenter, university-based study, 126 patients with no history of ocular disease were enrolled (78 diabetics without retinopathy and 48 nondiabetics). Optical coherence tomography measurements were performed using Stratus OCT. Statistical comparisons of center point foveal thickness and mean foveal thickness were made using generalized estimating equations adjusting for diabetic status, race, age, and gender.Results: The study population consisted of 36% male subjects, 39% Caucasian, 33% African-American, and 28% Hispanic. Mean foveal thickness was 191.6 ...

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    1-11 of 11
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    Progressive changes from idiopathic macular telangiectasia seen with spectral domain optical coherence tomography Characterization of macular lesions in punctate inner choroidopathy with spectral domain optical coherence tomography Detection of New-Onset Choroidal Neovascularization Using Optical Coherence Tomography: The Amd Doc Study Retinal optical coherence tomography manifestations of intraocular lymphoma Sclerochoroidal Calcifications Imaged Using Enhanced Depth Imaging Optical Coherence Tomography Comparison of Time Domain and Spectral Domain Optical Coherence Tomography in Measurement of Macular Thickness in Macular Edema Secondary to Diabetic Retinopathy and Retinal Vein Occlusion Longitudinal spectral domain optical coherence tomography changes in eyes with intraocular lymphoma SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY EVALUATION OF RETINAL STRUCTURE IN PATIENTS WITH SUSACS SYNDROME Diurnal variation of choriocapillaris vessel flow density in normal subjects measured using optical coherence tomography angiography Carotid Disease and Retinal Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes: The Fremantle Diabetes Study Phase II Retinal Vascular Density on Optical Coherence Tomography Angiography and Age-related Central and Peripheral Hearing Loss in a Southern Italian Older Population Optical coherence tomography outcomes from SPRINT-MS, a multicenter, randomized, double-blind trial of ibudilast in progressive multiple sclerosis