1. Articles from Sandrine A. Zweifel

    1-8 of 8
    1. En Face Optical Coherence Tomography Imaging Ellipsoid Zone Regeneration in Laser-Induced and Solar Maculopathies

      En Face Optical Coherence Tomography Imaging Ellipsoid Zone Regeneration in Laser-Induced and Solar Maculopathies

      The purpose of the study was to analyze imaging findings in spectral domain en face optical coherence tomography (SD OCT) in patients with laser‐induced and solar maculopathies focusing on the possible regeneration of the ellipsoid zone. In a retrospective case series of 3 patients (4 eyes) with solar maculopathy and 2 patients (3 eyes) with laser‐induced maculopathy who underwent a comprehensive ocular examination, ellipsoid zone (EZ) was segmented from SD OCT data. Evaluation of EZ in en face OCT revealed a hyporeflective lesion surrounded by a hyperreflective border. The area of EZ alteration was measured manually in en ...

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    2. Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring

      Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring

      Purpose : To study a novel and fast optical coherence tomography (OCT) device for home-based monitoring in age-related macular degeneration (AMD) in a small sample yielding sparse OCT (spOCT) data and to compare the device to a commercially available reference device. Methods : In this prospective study, both eyes of 31 participants with AMD were included. The subjects underwent scanning with an OCT prototype and a spectral-domain OCT to compare the accuracy of the central retinal thickness (CRT) measurements. Results : Sixty-two eyes in 31 participants (21 females and 10 males) were included. The mean age was 79.6 years (age range, 69 ...

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    3. THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY

      THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To analyze submacular perforating scleral vessels (PSVs) using enhanced depth imaging spectral domain optical coherence tomography (EDI-SDOCT). Methods: Twenty-two eyes of 11 healthy women were included in this retrospective study. Central EDI-SDOCT scans (3 x 4.5 x 1.9 mm, 13.5 mm2 scan area) were acquired and postprocessed by denoising, manual sclera segmentation, and PSV investigated by five graders. Results: Mean age was 22.4 +/- 6.2 years. Mean refractive error was -0.44 +/- 0.8 diopters. Mean axial length was 23.08 +/- 0.63 mm. The coefficient of agreement for grading was good. Mean number of ...

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    4. Spectral-Domain Optical Coherence Tomography Staging and Autofluorescence Imaging in Achromatopsia

      Spectral-Domain Optical Coherence Tomography Staging and Autofluorescence Imaging in Achromatopsia

      Importance Evidence is mounting that achromatopsia is a progressive retinal degeneration, and treatments for this condition are on the horizon. Objectives To categorize achromatopsia into clinically identifiable stages using spectral-domain optical coherence tomography and to describe fundus autofluorescence imaging in this condition. Design, Setting, and Participants A prospective observational study was performed between 2010 and 2012 at the Edward S. Harkness Eye Institute, New York-Presbyterian Hospital. Participants included 17 patients (aged 10-62 years) with full-field electroretinography-confirmed achromatopsia. Main Outcomes and Measures Spectral-domain optical coherence tomography features and staging system, fundus autofluorescence and near-infrared reflectance features and their correlation to optical ...

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    5. Enhanced Depth Imaging Optical Coherence Tomography of the Sclera in Dome-Shaped Macula

      Enhanced Depth Imaging Optical Coherence Tomography of the Sclera in Dome-Shaped Macula
      Purpose: To examine the posterior anatomic structure of eyes with dome-shaped macula using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT). Design: Retrospective observational case series. Methods: Patients with dome-shaped macula, a condition defined as convex elevation of the macula as compared with the surrounding staphylomatous region in a highly myopic eye, were identified through routine examinations using optical coherence tomography (OCT). EDI-OCT was used to examine their posterior anatomic changes. The scleral thickness was measured from the outer border of the choroid to the outer scleral border under the fovea and 3000 μm temporal to the fovea. Results: The ...
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    6. High-Resolution Optical Coherence Tomography Findings in Optic Pit Maculopathy

      High-Resolution Optical Coherence Tomography Findings in Optic Pit Maculopathy

      Purpose: The purpose of this study was to characterize retinal manifestations of optic pit maculopathy using high-resolution optical coherence tomography. Methods: Consecutive patients with optic pit maculopathy, diagnosed by their typical appearance by ophthalmoscopy, were imaged by color fundus photography and optical coherence tomography. The location and characteristics of any fluid within and under the retina were determined. Results: The mean age of the 16 patients (7 women) was 35.9 years (standard deviation: 18.5 years). The visual acuity ranged from 20/20 to 20/1000 (median, 20/200). Retinal detachment was found in 11 eyes (69%), intraretinal fluid ...

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    7. Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding

      Objective  To describe tubular structures found in the outer retina seen in a variety of retinal disorders. Methods  Sixty-nine eyes of 63 patients were examined with spectral-domain optical coherence tomography. Optical coherence tomography C-scans were correlated with their corresponding B-scans. The prevalence, number, size, and shape of the tubular structures were determined. Results  Branching tubules were identified in the outer retina of 54 patients with age-related macular degeneration and in 9 patients with other diagnoses. The tubules appeared as round or ovoid hyporeflective spaces with hyperreflective borders on the B-scans, measuring 40 to 140 µm high and 40 to 2260 ...
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    8. Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding

      Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding

      Objective To describe tubular structures found in the outer retina seen in a variety of retinal disorders. Methods Sixty-nine eyes of 63 patients were examined with spectral-domain optical coherence tomography. Optical coherence tomography C-scans were correlated with their corresponding B-scans. The prevalence, number, size, and shape of the tubular structures were determined. Results Branching tubules were identified in the outer retina of 54 patients with age-related macular degeneration and in 9 patients with other diagnoses. The tubules appeared as round or ovoid hyporeflective spaces with hyperreflective borders on the B-scans, measuring 40 to 140 Μm high and 40 to 2260 ...

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    1-8 of 8
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  2. Topics in the News

    1. (4 articles) University Hospital Zurich
    2. (4 articles) Richard F. Spaide
    3. (3 articles) LuEsther T. Mertz Retinal Research Center
    4. (2 articles) Columbia University
    5. (2 articles) Hendrik P. N. Scholl
    6. (2 articles) K. Bailey Freund
    7. (2 articles) Adnan Tufail
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    High-Resolution Optical Coherence Tomography Findings in Optic Pit Maculopathy Enhanced Depth Imaging Optical Coherence Tomography of the Sclera in Dome-Shaped Macula Spectral-Domain Optical Coherence Tomography Staging and Autofluorescence Imaging in Achromatopsia Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding THREE-DIMENSIONAL ANALYSIS OF SUBMACULAR PERFORATING SCLERAL VESSELS BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY Safety and Feasibility of a Novel Sparse Optical Coherence Tomography Device for Patient-Delivered Retina Home Monitoring En Face Optical Coherence Tomography Imaging Ellipsoid Zone Regeneration in Laser-Induced and Solar Maculopathies Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT Inadequate Intimal Angiogenesis as a Source of Coronary Plaque Instability Comparison of optical coherence tomography angiography results of adult patients with Familial Mediterranean fever and healthy individuals Intravascular ultrasound or optical coherence tomography-defined anatomic severity and hemodynamic severity assessed by coronary physiologic indices Optical coherence tomography in the assessment of cutaneous cancer margins of the face: an immediate ex vivo study