1. Articles from Tito Fiore

    1-9 of 9
    1. Optical coherence tomography angiography in age-related macular degeneration: The game changer

      Optical coherence tomography angiography in age-related macular degeneration: The game changer

      Optical coherence tomography angiography is one of the biggest advances in ophthalmic imaging. It enables a depth-resolved assessment of the retinal and choroidal blood flow, far exceeding the levels of detail commonly obtained with dye angiographies. One of the first applications of optical coherence tomography angiography was in detecting the presence of choroidal neovascularization in age-related macular degeneration and establishing its position in relation to the retinal pigmented epithelium and Bruch’s membrane, and thereby classifying the CNV as type 1, type 2, type 3, or mixed lesions. Optical coherence tomography angiograms, due to the longer wavelength used by optical ...

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    2. Outer Retinal and Choroidal Evaluation in Multiple Evanescent White Dot Syndrome (MEWDS): An Enhanced Depth Imaging Optical Coherence Tomography Study

      Outer Retinal and Choroidal Evaluation in Multiple Evanescent White Dot Syndrome (MEWDS): An Enhanced Depth Imaging Optical Coherence Tomography Study

      Purpose : To perform an analysis of optical coherence tomography (OCT) abnormalities in patients with MEWDS, during the acute and recovery stages, using enhanced depth imaging-OCT (EDI-OCT). Methods : A retrospective case series of five patients with MEWDS was included. EDI-OCT imaging was evaluated to detect retinal and choroidal features. Results : In the acute phase, focal impairment of the ellipsoid zone and external limiting membrane, hyperreflective dots in the inner choroid, and full-thickness increase of the choroidal profile were observed in the affected eye; disappearance of these findings and restoration of the choroidal thickness ( p = 0.046) was appreciated in the recovery ...

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    3. Full-thickness choroidal thinning as a feature of Fuchs Uveitis Syndrome: quantitative evaluation of the choroid by Enhanced Depth Imaging Optical Coherence Tomography in a cohort of consecutive patients

      Full-thickness choroidal thinning as a feature of Fuchs Uveitis Syndrome: quantitative evaluation of the choroid by Enhanced Depth Imaging Optical Coherence Tomography in a cohort of consecutive patients

      Purpose To perform a quantitative analysis of choroidal thickness in patients with Fuchs Uveitis Syndrome (FUS) using enhanced depth imaging optical coherence tomography (EDI-OCT). Methods All patients underwent comprehensive ophthalmic examination, including best-corrected visual acuity, slit-lamp biomicroscopy, applanation tonometry, axial length measurements with a swept-source biometer (IOLMaster 700, Carl Zeiss Medic AG, Jena, Germany) and macular 30° linear EDI- B-scan SD-OCT section (Spectralis HRAII+OCT, Heidelberg Engineering, Heidelberg, Germany) in both eyes. Analysis of choroidal thickness was performed at three different locations: subfoveally, 750 μm nasally, and 750 μm temporally to the fovea. Patients having received any surgery or intravitreal ...

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    4. Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach

      Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach

      The aim of the study was to report the clinical utility of optical coherence tomography angiography (OCT-A) in characterizing and differentiating inflammatory lesions and choroidal neovascularization (CNV) in multifocal choroiditis (MFC). A patient affected by MFC complaining central visual loss and scotoma in his left eye was fully investigated with dye-based angiographies, structural OCT and OCT-A. A reactivation of macular CNV was initially suspected, while OCT-A revealed the absence of any decorrelation signal both over the retinal pigment epithelium (RPE) and between RPE and Bruchs’ membrane. OCT-A is a promising tool in detecting inflammatory CNV and in differentiating CNV from ...

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    5. Automated Quantitative Analysis of Retinal Microvasculature In Normal Eyes On Optical Coherence Tomography Angiography

      Automated Quantitative Analysis of Retinal Microvasculature In Normal Eyes On Optical Coherence Tomography Angiography

      Purpose To describe a new automated quantitative technique for displaying and analyzing macular vascular perfusion using optical coherence tomography angiography (OCT-A) and to determine a normative data set, which might be used as reference in identifying progressive changes due to different retinal vascular diseases. Design Reliability study. Methods A retrospective review of forty-seven eyes of 47 consecutive healthy subjects imaged with a spectral domain OCT-A device was performed in a single institution. Full-spectrum amplitude-decorrelation angiography generated OCT-angiograms of the retinal superficial and deep capillary plexuses. A fully-automated custom built software was used to provide quantitative data on the foveal avascular ...

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    6. Influence of Pseudophakic Lens Capsule Opacification on Spectral Domain and Time Domain Optical Coherence Tomography Image Quality

      Influence of Pseudophakic Lens Capsule Opacification on Spectral Domain and Time Domain Optical Coherence Tomography Image Quality

      Purpose : To evaluate the influence of posterior capsule opacification (PCO) on optical coherence tomography (OCT) acquisition of macular retinal thickness (RT) and volume using time domain OCT (TD-OCT) and spectral domain OCT (SD-OCT). Materials and methods : We studied 37 eyes of 31 patients with PCO. Each patient underwent an evaluation with TD-OCT and with SD-OCT before and after Nd:YAG capsulotomy. We recorded RT and retinal volume in the macular area using only good quality images . Results : Best corrected visual acuity improved in all eyes after Nd:YAG capsulotomy, with the degree of improvement ranging from 0.3 ±   0.7 ...

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    7. Repeatability and Reproducibility of Retinal Thickness Measurements in Diabetic Patients with Spectral Domain Optical Coherence Tomography

      Repeatability and Reproducibility of Retinal Thickness Measurements in Diabetic Patients with Spectral Domain Optical Coherence Tomography

      Background : To determine the repeatability and reproducibility of optical coherence tomography (OCT) Spectralis retinal thickness measurements in diabetic patients with clinically significant macular edema (CSME). Methods : Twelve eyes of 12 volunteers (without macular pathology – control group) and 21 eyes of 21 diabetic patients with CSME were included in the study. Reproducibility, repeatability, intraclass correlation coefficients (ICCs) and intrasession correlation coefficients were tested with 20 × 15 degree raster scans consisting of 19 high-resolution line scans that were repeated three times by two experienced examiners. Results : In the control group, examining all regions, coefficient of repeatability was less than 1.1%, while ...

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    8. Macular Thickness Measured by Optical Coherence Tomography in a Healthy Population Before and After Uncomplicated Cataract Phacoemulsification Surgery

      Purpose: To examine macular changes before and after uncomplicated cataract surgery in a healthy population. Material and Methods: In a prospective study, we evaluated 62 eyes of healthy patients having elective cataract phacoemulsification. We performed optical coherence tomography (OCT) measurements preoperatively and at 3, 6, 12, 20, and 28 weeks after surgery. The retinal map was divided into minimal foveal thickness, a central 1-mm disk area, and two peripheral ring areas with diameters of 3mm and 6mm, respectively, and centered on the fovea. We compared the postoperative OCT values against the respective preoperative values. Results: Two eyes (3.2%) developed ...
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    1-9 of 9
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  2. Topics in the News

    1. (3 articles) University of Perugia
    2. (3 articles) Gabriel J. Coscas
    3. (1 articles) Centre Hospitalier Intercommunal de Créteil
    4. (1 articles) L V Prasad Eye Institute
    5. (1 articles) Heidelberg Engineering
    6. (1 articles) University of Washington
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    Repeatability and Reproducibility of Retinal Thickness Measurements in Diabetic Patients with Spectral Domain Optical Coherence Tomography Influence of Pseudophakic Lens Capsule Opacification on Spectral Domain and Time Domain Optical Coherence Tomography Image Quality Automated Quantitative Analysis of Retinal Microvasculature In Normal Eyes On Optical Coherence Tomography Angiography Deep inside Multifocal Choroiditis: an Optical Coherence Tomography Angiography approach Full-thickness choroidal thinning as a feature of Fuchs Uveitis Syndrome: quantitative evaluation of the choroid by Enhanced Depth Imaging Optical Coherence Tomography in a cohort of consecutive patients Outer Retinal and Choroidal Evaluation in Multiple Evanescent White Dot Syndrome (MEWDS): An Enhanced Depth Imaging Optical Coherence Tomography Study Depth-Resolved Imaging of Papillary Vitreoretinal Neovascularization: OCT-Angiography Assessment in Ocular Ischemic Syndrome Optical coherence tomography angiography in age-related macular degeneration: The game changer Carotid Disease and Retinal Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes: The Fremantle Diabetes Study Phase II Retinal Vascular Density on Optical Coherence Tomography Angiography and Age-related Central and Peripheral Hearing Loss in a Southern Italian Older Population Optical coherence tomography outcomes from SPRINT-MS, a multicenter, randomized, double-blind trial of ibudilast in progressive multiple sclerosis Microvascular alterations in children with optic disk drusen evaluated by optical coherence tomography angiography