1. Articles from Tony Ko

    1-8 of 8
    1. RETINAL VASCULAR PERFUSION DENSITY MAPPING USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN NORMALS AND DIABETIC RETINOPATHY PATIENTS

      RETINAL VASCULAR PERFUSION DENSITY MAPPING USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN NORMALS AND DIABETIC RETINOPATHY PATIENTS

      Purpose: To describe a new method of retinal vascular perfusion density mapping using optical coherence tomography angiography and to compare current staging of diabetic retinopathy based on clinical features with a new grading scale based on perifoveal perfusion densities. Methods: A retrospective review was performed on subjects with diabetic retinopathy and age-matched controls imaged with a spectral domain optical coherence tomography system (Optovue XR Avanti, Fremont, CA). Split-spectrum amplitude-decorrelation angiography (SSADA) generated optical coherence tomography angiograms of the superficial retinal capillaries, deep retinal capillaries, and choriocapillaris. Skeletonized optical coherence tomography angiograms were used to create color-coded perfusion maps and capillary ...

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    2. Correlation between optic disc perfusion and glaucomatous severity in patients with open-angle glaucoma: an optical coherence tomography angiography study

      Correlation between optic disc perfusion and glaucomatous severity in patients with open-angle glaucoma: an optical coherence tomography angiography study

      Purpose To explore how optic disc perfusion varies in patients with open-angle glaucoma (OAG) and how this correlates with glaucoma severity. Methods We performed a prospective and cross-sectional observational study that included 62 eyes from 62 patients with OAG, divided into three groups according to their visual field (VF) results, and 20 eyes from 20 normal control subjects. Optic disc perfusion was studied using optical coherence tomography angiography (angio-OCT), and flow index and vessel density were determined. The VF, mean deviation (MD), pattern standard deviation (PSD), retinal nerve fiber layer (RNFL) thickness, and ganglion cell complex (GCC) thickness were also ...

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    3. Enhanced biometry using optical coherence tomography

      Enhanced biometry using optical coherence tomography

      An imaging method is disclosed. An imaging method according to some embodiments can include obtaining a plurality of measurements of an eye for at least one location by scanning optical radiation across the eye; determining a preferred measurement axis from the plurality of measurements; and processing the plurality of measurements to obtain information of the eye.

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    4. Scanning and processing using optical coherence tomography

      Scanning and processing using optical coherence tomography

      In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 ...

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    5. Enhanced Biometry Using Optical Coherence Tomography

      Enhanced Biometry Using Optical Coherence Tomography

      An imaging method is disclosed. An imaging method according to some embodiments can include obtaining a plurality of measurements of an eye for at least one location by scanning optical radiation across the eye; determining a preferred measurement axis from the plurality of measurements; and processing the plurality of measurements to obtain information of the eye.

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    6. Methods and apparatus for optical coherence tomography scanning

      Methods and apparatus for optical coherence tomography scanning

      Optical coherence tomography performs cross-sectional imaging, three-dimensional imaging, or data acquisition in materials or biological tissue by measuring the magnitude and time delay of backscattered or backreflected light from inside the sample. OCT performs imaging or measurement by directing a light beam at the sample, measuring the backscattering or backreflected signal from the sample as a function of the optical delay (known as an axial scan or A-scan), and scanning the OCT beam incident on the tissue or material to generate a two or three dimensional dataset which represents cross-sectional or volumetric information about the internal structure of the sample ...

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    7. Methods and apparatus for optical coherence tomography scanning

      Methods and apparatus for optical coherence tomography scanning
      In one aspect, the invention relates to a method of acquiring optical coherence tomographic data from a sample. The method includes the steps of scanning a first location on the sample to obtain a first set of optical coherence tomographic data, scanning a second location on the sample to obtain a second set of optical coherence tomographic data, and defining a fiducial position relative to a location on the sample using one of the two sets of optical coherence tomographic data. In one embodiment, the first set of optical coherence tomographic data is survey data. However, in another embodiment the ...
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    8. Imaging needle for optical coherence tomography

      Imaging needle for optical coherence tomography
      We describe a miniature optical coherence tomography (OCT) imaging needle that can be inserted into solid tissues and organs to permit interstitial imaging of their internal microstructures with micrometer scale resolution and minimal trauma. A novel rotational coupler with a glass capillary tube is also presented that couples light from a rotating single-mode fiber to a stationary one. A prototype needle with a 27-gauge 410-mm outer diameter has been developed and is demonstrated for in vivo imaging. The OCT needle can be integrated with standard excisional biopsy devices and used for OCT-guided biopsy.
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    1-8 of 8
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  2. Topics in the News

    1. (5 articles) Tony H. Ko
    2. (5 articles) Optovue
    3. (3 articles) Massachusetts Institute of Technology
    4. (3 articles) Jay Wei
    5. (3 articles) James G. Fujimoto
    6. (2 articles) Vivek J. Srinivasan
    7. (2 articles) Robert A. Huber
    8. (2 articles) Michael R. Hee
    9. (2 articles) Maciej Wojtkowski
    10. (1 articles) Costas D. Pitris
    11. (1 articles) Technical University of Denmark (DTU)
    12. (1 articles) Columbia University
    13. (1 articles) Peking University
    14. (1 articles) Capital Medical University
    15. (1 articles) Cardiovascular Research Foundation
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    Imaging needle for optical coherence tomography Methods and apparatus for optical coherence tomography scanning Methods and apparatus for optical coherence tomography scanning Enhanced Biometry Using Optical Coherence Tomography Scanning and processing using optical coherence tomography Enhanced biometry using optical coherence tomography Correlation between optic disc perfusion and glaucomatous severity in patients with open-angle glaucoma: an optical coherence tomography angiography study RETINAL VASCULAR PERFUSION DENSITY MAPPING USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN NORMALS AND DIABETIC RETINOPATHY PATIENTS A case report of a coronary myocardial bridge with impaired full-cycle ratio during dobutamine challenge Diagnosis of chronic stage of hypertensive retinopathy based on spectral domain optical coherence tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Determination of peripapillary vessel density in optic disc drusen using EDI-OCT and OCT angiography