1. Articles from Yasuo Yanagi

    1-8 of 8
    1. Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy

      Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy

      Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with anti–vascular endothelial growth factor monotherapy or combined with photodynamic therapy . Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer retina and choriocapillaris using automated segmentation. The authors analyzed the presence of pachyvessels using a 10.4- μ m segment through Haller layer . The changes in each layer were compared ...

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    2. IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To assess the ability of optical coherence tomography (OCT) alone and in combination with OCT angiography (OCTA) to differentiate polypoidal choroidal vasculopathy (PCV) from neovascular age-related macular degeneration , as compared to fluorescein angiography and indocyanine green angiography. Methods: This is a cross-sectional study. All participants had a standardized history, clinical examination including measurement of best-corrected visual acuity, slit-lamp biomicroscopy, and indirect fundus examination, and underwent standardized imaging (color photography, fluorescein and indocyanine green angiography, OCT, and OCTA) after predefined protocols. We used a 2-step approach (Step 1: spectral domain OCT; Step 2: addition of OCTA) combining structural OCT and ...

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    3. COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY

      COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY

      Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with anti-vascular endothelial growth factor monotherapy or combined with photodynamic therapy. Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer retina and choriocapillaris using automated segmentation. The authors analyzed the presence of pachyvessels using a 10.4-[mu]m segment through Haller layer. The changes in each layer were compared ...

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    4. CHARACTERIZATION AND DIFFERENTIATION OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      CHARACTERIZATION AND DIFFERENTIATION OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Purpose: To determine the correlation and agreement between swept-source optical coherence tomography angiography (SS-OCT-A) with fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral domain OCT (SD-OCT) in characterizing polypoidal choroidal vasculopathy (PCV) and in differentiating eyes with typical age-related macular degeneration (t-AMD). Methods: This study included 32 and 54 eyes with t-AMD and PCV, respectively, who underwent SS-OCT-A, SD-OCT, fluorescein angiography, and indocyanine green angiography. The images from these four techniques were compared. Results: On SS-OCT-A, flow signals with vascular network configuration were detected in 81.2% and 77.8% of eyes with t-AMD and PCV, respectively. 40.4 ...

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      Mentions: Tien Yin Wong
    5. Fundus autofluorescence and retinal structure as determined by spectral domain optical coherence tomography, and retinal function in retinitis pigmentosa

      Fundus autofluorescence and retinal structure as determined by spectral domain optical coherence tomography, and retinal function in retinitis pigmentosa
      Abstract Background  To investigate the association between fundus autofluorescence (FAF) and retinal structure and function in retinitis pigmentosa (RP). Methods  For image acquisition, HRA2 (Heidelberg Engineering) and 3D-OCT1000 (Topcon Corp.) were used. Based on FAF examination, 88 eyes of 44 RP patients were categorized into three types. The area within the hyperautofluorescent ring and the area of preserved retinal autofluorescence with FAF was calculated. The association between the pattern of FAF and the residual area of the junction between the inner and outer segments of the photoreceptors (IS/OS line), and the relationship between the area within hyperautofluorescent ring, the ...
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    6. Evaluation of a partial retinal surface tear by optical coherence tomography

      Evaluation of a partial retinal surface tear by optical coherence tomography
      Differential diagnosis of retinal hemorrhage and partial tear of the retinal surface may be difficult in some cases. A 62-year-old woman was mistakenly followed-up for small retinal hemorrhages for more than 1 year. Blocked fluorescence specific to retinal hemorrhage was not observed by fluorescein angiography (FAG). Optical coherence tomography (OCT) clearly showed defects of the retinal surface indicating partial tears of the surface at the vitreoretinal juncture and not hemorrhage. OCT is a useful and noninvasive device for the differential diagnosis of retinal hemorrhage and partial tear of the retinal surface.
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    7. Vitreopapillary Traction Diagnosed by Spectral Domain Optical Coherence Tomography

      Vitreopapillary Traction Diagnosed by Spectral Domain Optical Coherence Tomography
      This report describes a case of vitreopapillary traction with right inferior altitudinal defect similar to anterior ischemic optic neuropathy. A 35-year-old man with inferior altitudinal defect in his right eye was referred. The right optic disc was elevated and the superior disc margin was blurred. Spectral domain optical coherence tomography (SD-OCT) of the right optic disc showed the vitreous cortex was highly reflective and pulling the optic disc margin superiorly. The posterior hyaloid membrane on the nasal side of the optic disc was less reflective than that superior to the disc, suggesting that vitreopapillary traction contributed to this condition. During ...
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    8. Nerve fiber layer thickness in exudative age-related macular degeneration in Japanese patients

      Purpose To examine the peripapillary retinal nerve fiber (RNFL) thickness in Japanese patients with two major forms of exudative age-related macular degeneration (AMD), i.e., typical AMD and polypoidal choroidal vasculopathy (PCV). Methods This is a prospective observational consecutive study. One hundred patients diagnosed with unilateral exudative AMD, with the fellow eyes free of exudative change, were included. Peripapillary RNFL thickness was measured using three-dimensional Fourier-domain optical coherence tomography (3D-OCT). Peripapillary RNFL thickness was compared between the affected eyes and fellow eyes in 100 patients. Results RNFL thickness in the eyes with exudative AMD did not differ significantly from the ...
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    1-8 of 8
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    1. (4 articles) Tien Yin Wong
    2. (3 articles) Singapore Eye Research Institute
    3. (3 articles) University of Tokyo
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    Vitreopapillary Traction Diagnosed by Spectral Domain Optical Coherence Tomography Evaluation of a partial retinal surface tear by optical coherence tomography Fundus autofluorescence and retinal structure as determined by spectral domain optical coherence tomography, and retinal function in retinitis pigmentosa CHARACTERIZATION AND DIFFERENTIATION OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy Optical coherence tomography angiography of foveal neovascularisation in proliferative diabetic retinopathy Treating port wine stain birthmarks using dynamic optical coherence tomography-guided setting Repeatability of quantitative measurements of retinal layers with SD-OCT and agreement between vertical and horizontal scan protocols in healthy eyes Perimeter Medical Imaging Closes Oversubscribed $C4.4M Financing Time-domain optical coherence tomography system based on moving-optical-wedge interferometer