1. Articles from Ferdinando Bottoni

    1-9 of 9
    1. The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission

      The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission

      Background To explore the role of foveal and parafoveal Müller cells in the morphology and pathophysiology of tractional macular disorders with a mathematical model of mechanical force transmission. Methods In this retrospective observational study, spectral-domain optical coherence tomography images of tractional lamellar macular holes and patients with myopic foveoschisis were reviewed and analysed with a mathematical model of force transmission. Parafoveal z-shaped Müller cells were modelled as a structure composed of three rigid rods, named R1, R2 and R3. The angle formed between the rods was referred to as θ . R1, R2 and R3 lengths as well as the ...

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    2. Looking Outside The Maculaa Wide-Field Optical Coherence Tomography Study

      Looking Outside The Maculaa Wide-Field Optical Coherence Tomography Study

      Purpose: To evaluate baseline features and morphologic changes of vitreoretinal adhesion and outer retinal layers outside the macula after intravitreal ocriplasmin injection. To study the relation between vitreous detachment and attenuation of retinal outer segments signal. Methods: Retrospective cases series of 15 eyes. Each eye was scanned with the 55° wide-field optical coherence tomography lens in 6 different locations, three horizontal B-scan (central, temporal, and nasal) and three vertical B-scan (central, superior, and inferior) at baseline, 1 week, 1 month, 3 months, and 6 months after injection. Results: After ocriplasmin injection, vitreomacular traction (VMT) resolved in 12 patients (80%), 3 ...

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    3. The Relationship Between Blue-Fundus Autofluorescence and Optical Coherence Tomography in Eyes With Lamellar Macular Holes

      The Relationship Between Blue-Fundus Autofluorescence and Optical Coherence Tomography in Eyes With Lamellar Macular Holes

      Purpose : The purpose of this study was to evaluate the relationship between blue-fundus autofluorescence (B-FAF) and optical coherence tomography (OCT) in eyes with lamellar macular holes (LMHs). Methods : this was a multicenter, observational case series. Ninety-two eyes with LMH associated with the standard epiretinal membrane (ERM) or lamellar hole–associated epiretinal proliferation (LHEP) were evaluated. The eyes must also present an area of increased autofluorescence on B-FAF. Results : The ERM-alone group and the LHEP group differed with respect to the following variables: logarithm of the minimum angle of resolution best-corrected visual acuity (0.13 ± 0.13 vs. 0.25 ± 0 ...

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    4. OCRIPLASMIN FOR VITREOMACULAR TRACTION: LOOKING OUTSIDE THE MACULA: A Wide-Field Optical Coherence Tomography Study

      OCRIPLASMIN FOR VITREOMACULAR TRACTION: LOOKING OUTSIDE THE MACULA: A Wide-Field Optical Coherence Tomography Study

      Purpose: To evaluate baseline features and morphologic changes of vitreoretinal adhesion and outer retinal layers outside the macula after intravitreal ocriplasmin injection. To study the relation between vitreous detachment and attenuation of retinal outer segments signal. Methods: Retrospective cases series of 15 eyes. Each eye was scanned with the 55[degrees] wide-field optical coherence tomography lens in 6 different locations, three horizontal B-scan (central, temporal, and nasal) and three vertical B-scan (central, superior, and inferior) at baseline, 1 week, 1 month, 3 months, and 6 months after injection. Results: After ocriplasmin injection, vitreomacular traction (VMT) resolved in 12 patients (80 ...

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    5. Optical Coherence Tomography in Eyes with Vitreomacular Traction

      Optical Coherence Tomography in Eyes with Vitreomacular Traction

      We read with interest the article “Highly reflective foveal region in optical coherence tomography in eyes with vitreomacular traction or epiretinal membrane” by Tsunoda et al. The authors reported the presence of a highly reflective deposit (named “cotton ball sign”) on spectral-domain optical coherence tomography (SD-OCT) scanning in 63.8% of the eyes (30/47) with an epiretinal membrane (ERM) and in 100% (7/7) of eyes with vitreomacular traction (VMT). They stated that related articles were searched on PubMed and none was found describing the same feature. We believe the so-called “cotton ball sign” related to ERM or VMT ...

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    6. The natural history of lamellar macular holes: a spectral domain optical coherence tomography study

      The natural history of lamellar macular holes: a spectral domain optical coherence tomography study

      BACKGROUND: To study the evolution of lamellar macular holes (LMHs) using spectral domain-optical coherence tomography (SD-OCT). METHODS: Thirty-four consecutive patients diagnosed with a LMH were followed prospectively at Sacco University Hospital from October 2008 to January 2011. Inclusion criteria were a foveal defect on SD-OCT with residual foveal tissue above the retinal pigment epithelium and corresponding hyperautofluorescence on fundus autofluorescence imaging. Epiretinal membranes (ERMs) were categorized by SD-OCT at baseline as two different types: normal and thicker than normal. Best corrected visual acuity (BCVA) and SD-OCT findings were collected and compared at baseline and every 6 months thereafter. Active eye ...

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    7. The dynamic healing process of idiopathic macular holes after surgical repair: a spectral-domain optical coherence tomography study

      The dynamic healing process of idiopathic macular holes after surgical repair: a spectral-domain optical coherence tomography study
      Purpose: To analyze progressive changes of the outer retina after vitrectomy for macular hole (MH) repair. Methods: Nineteen consecutive patients underwent vitrectomy for idiopathic MH. Spectral domain optical coherence tomography (SD-OCT) examinations were performed pre- and post-operatively during follow-up visits at 1, 3, 6, 9, and 12 months. Active eye tracking technology ensured that the same scanning location was identified each time. Results: Ten eyes showed a normal external limiting membrane (ELM) at 1 month after surgery, and 15 eyes at 3 months. The ELM was already continuous in 79% of the eyes with persistent outer foveal defects during follow-up ...
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    8. Spectral-domain OCT evaluation of Nd:YAG laser treatment for Valsalva retinopathy

      Abstract Purpose  To describe the spectral-domain optical coherence tomography (SD-OCT) findings in a patient with a premacular hemorrhage due to Valsalva retinopathy treated with Nd:YAG laser. Methods  Serial SD-OCT examinations were performed before and after Nd:YAG laser treatment to identify the cleavage plane of blood accumulation, as well as the exact location of the areas targeted by the laser spots and the different involvement of the affected retinal layers. Results  The SD-OCT scan above the level of settled blood showed that the cleavage plane was located under the internal limiting membrane (ILM). A raster box of 48 horizontal ...
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    9. Diagnosis of macular pseudoholes and lamellar macular holes: is optical coherence tomography the gold standard?

      Aims: To assess fundus autofluorescence (AF) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH) evaluated with optical coherence tomography (OCT) as the gold standard. Methods: We reviewed the files of 50 eyes of 46 consecutive patients who were diagnosed by OCT as having a foveal defect with residual retinal tissue at the bottom. Retinal thickness was measured at the foveal center and 750 µm temporally and nasally to differentiate further MPH and LMH. The corresponding corrected AF images were then evaluated. Eyes with either macular pucker or stage 1a impending macular hole served as controls ...
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      Mentions: Mario Cigada
    1-9 of 9
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    1. (6 articles) University of Milan
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    The dynamic healing process of idiopathic macular holes after surgical repair: a spectral-domain optical coherence tomography study The natural history of lamellar macular holes: a spectral domain optical coherence tomography study Optical Coherence Tomography in Eyes with Vitreomacular Traction OCRIPLASMIN FOR VITREOMACULAR TRACTION: LOOKING OUTSIDE THE MACULA: A Wide-Field Optical Coherence Tomography Study The Relationship Between Blue-Fundus Autofluorescence and Optical Coherence Tomography in Eyes With Lamellar Macular Holes Looking Outside The Maculaa Wide-Field Optical Coherence Tomography Study The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission Remote scanning for ultra-large field of view in wide-field microscopy and full-field OCT Inadequate Intimal Angiogenesis as a Source of Coronary Plaque Instability Comparison of optical coherence tomography angiography results of adult patients with Familial Mediterranean fever and healthy individuals Intravascular ultrasound or optical coherence tomography-defined anatomic severity and hemodynamic severity assessed by coronary physiologic indices Optical coherence tomography in the assessment of cutaneous cancer margins of the face: an immediate ex vivo study