1. Articles from Ming Li

    1-10 of 10
    1. Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography

      Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography

      Purpose . To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods . Twenty participants (4 males and 16 females, 23.0 ± 3.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear. The conjunctival overlap was ranked as the percentage of the edge covered by the conjunctiva. The frequency of occurrence for visualized peripheral ...

      Read Full Article
    2. Characterization of Soft Contact Lens Fitting Using Ultra-Long Scan Depth Optical Coherence Tomography

      Characterization of Soft Contact Lens Fitting Using Ultra-Long Scan Depth Optical Coherence Tomography

      Objectives . To evaluate the centration and movement of soft contact lenses and to verify the repeatability of two repeated measurements of the lens centration and movement using ultra-long scan depth optical coherence tomography (UL-OCT). Methods . A 1-day Acuvue® Define™ lens was tested on both eyes of 10 subjects (5 males and 5 females; mean age, 31.6 years). The centration and blink-induced movement of the contact lens were measured using UL-OCT at 5 min and 30 min after insertion. The measurements were repeated once at each checkpoint. Results . Good repeatability was found in the lens centration and movement between the ...

      Read Full Article
    3. Anterior Segment Biometry during Accommodation Imaged with Ultralong Scan Depth Optical Coherence Tomography

      Anterior Segment Biometry during Accommodation Imaged with Ultralong Scan Depth Optical Coherence Tomography

      Purpose: To measure by ultralong scan depth optical coherence tomography (UL-OCT) dimensional changes in the anterior segment of human eyes during accommodation.Design: Evaluation of diagnostic test or technology.Participants: Forty-one right eyes of healthy subjects with a mean age of 34 years (range, 22–41 years) and a mean refraction of −2.5±2.6 diopters were imaged in 2 repeated measurements at minimal and maximal accommodations.Methods: A specially adapted and designed UL-OCT instrument was used to image from the front surface of the cornea to the back surface of the crystalline lens. Custom software corrected the optical ...

      Read Full Article
    4. Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography

      Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography

      This study is designed to test the repeatability of the quantitative analysis of intraretinal layer thickness and cup-disc ratio of the optic nerve head using ultra-high resolution optical coherence tomography (UHR-OCT). Group A, containing 23 eyes of 12 healthy subjects, was imaged twice and group B, containing eight eyes of four subjects, was imaged three times. Intraretinal layers were segmented manually and the cup-to-disc ratio of the optic nerve head was analyzed. Custom-built automatic segmentation software was also used to segment a set of images for comparison. A total of nine intraretinal layers were visualized and extracted manually. With group ...

      Read Full Article
    5. Broadband superluminescent diode–based ultrahigh resolution optical coherence tomography for ophthalmic imaging

      Broadband superluminescent diode–based ultrahigh resolution optical coherence tomography for ophthalmic imaging

      Spectral domain optical coherence tomography (SD-OCT) with ultrahigh resolution can be used to measure precise structures in the context of ophthalmic imaging. We designed an ultrahigh resolution SD-OCT system based on broadband superluminescent diode (SLD) as the light source. An axial resolution of 2.2 μm in tissue, a scan depth of 1.48 mm, and a high sensitivity of 93 dB were achieved by the spectrometer designed. The ultrahigh-resolution SD-OCT system was employed to image the human cornea and retina with a cross-section image of 2048 × 2048 pixels. Our research demonstrated that ultrahigh -resolution SD-OCT can be achieved using ...

      Read Full Article
    6. Systems, devices and methods of broadband light sources with tunable spectrum

      Systems, devices and methods of broadband light sources with tunable spectrum
      Broadband light source systems, devices, and methods with a tunable spectrum are described by multiplexing a plurality of light sources, such as LEDs, with thin-film filters or diffraction gratings. A plurality of light sources with different or same wavelengths are multiplexed together to construct a combined broadband light source. A diffraction grating diffracts light beams from the plurality of light sources to a slit-shaped aperture, depending on selected light sources, the relative positions of the light sources to the slit-shaped aperture, and the type of grating to produce a tunable spectrum
      Read Full Article
    7. Ultra-High Resolution Optical Coherence Tomography for Imaging the Anterior Segment of the Eye

      Ultra-High Resolution Optical Coherence Tomography for Imaging the Anterior Segment of the Eye

      Developments in optical coherence tomography (OCT) have expanded its clinical applications for ultra-high resolution imaging of the anterior segment of the human eye. This review presents the latest advances for imaging the anterior segment of the eye using ultra-high resolution OCT (UHR-OCT). Unique applications of UHR-OCT technology in clinical and basic scientific laboratory research are discussed and a summary of the results is provided. The authors focused on the use of UHR-OCT for imaging of tear dynamics, contact lens interactions with the corneal surface, and in vivo histological diagnosis of disorders of the cornea, as well as the future direction ...

      Read Full Article
    8. Age-Related Changes in Tear Menisci Imaged by Optical Coherence Tomography

      Age-Related Changes in Tear Menisci Imaged by Optical Coherence Tomography
      Purpose. To determine age-related changes of tear menisci in healthy subjects and to compare tear variables between age-matched normals and dry eye subjects. Methods. Anterior segment optical coherence tomography was used to measure upper and lower tear menisci in healthy subjects (n = 197, 8-83 years) and in age-matched dry eye patients (n = 38, 19-72 years). Measured tear variables included the height and area of the tear meniscus. Tear meniscus volumes were calculated based on the cross-sectional areas of the tear menisci and the eyelid lengths. The age-related decrease rates of the tear menisci were also calculated. Results. There were significant ...
      Read Full Article
    9. A Comprehensive Comparison of Central Corneal Thickness Measurement

      A Comprehensive Comparison of Central Corneal Thickness Measurement
      Purpose. To assess the repeatability and reproducibility of central corneal thickness (CCT) measurements by high-resolution rotating Scheimpflug imaging (Pentacam, Oculus) and Fourier-domain optical coherence tomography (RTvue-100, Optovue) after laser in situ keratomileusis (LASIK) and to compare the agreement with ultrasound pachymetry (USP). Methods. Forty-seven eyes of 47 patients after LASIK were included in the study. The first examiner took two successive Pentacam and RTvue CCT measurements, and this was repeated once again by the second examiner to assess intraobserver and interobserver repeatability and reproducibility. After performing non-contact examinations, the corneas were measured by USP to compare the level of agreement ...
      Read Full Article
      Mentions: Optovue
    10. Extended scan depth optical coherence tomography for evaluating ocular surface shape

      Extended scan depth optical coherence tomography for evaluating ocular surface shape

      Spectral domain optical coherence tomography (SD-OCT) with extended scan depth makes it possible for quantitative measurement of the entire ocular surface shape. We proposed a novel method for ocular surface shape measurement using a custom-built anterior segment SD-OCT, which will serve on the contact lens fitting. A crosshair alignment system was applied to reduce the misalignment and tilting of the eye. An algorithm was developed to automatically segment the ocular surface. We also described the correction of the image distortion from the segmented dataset induced by the nontelecentric scanning system and tested the accuracy and repeatability. The results showed high ...

      Read Full Article
    1-10 of 10
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (8 articles) Wenzhou Medical College
    2. (8 articles) Meixiao Shen
    3. (7 articles) University of Miami
    4. (7 articles) Jianhua Wang
    5. (3 articles) Michael R. Wang
    6. (2 articles) Zhejiang University
    7. (2 articles) Aizhu Tao
    8. (1 articles) Sonia H. Yoo
    9. (1 articles) Optovue
    10. (1 articles) Bausch & Lomb
  3. Popular Articles

  4. Picture Gallery

    Extended scan depth optical coherence tomography for evaluating ocular surface shape Age-Related Changes in Tear Menisci Imaged by Optical Coherence Tomography A Comprehensive Comparison of Central Corneal Thickness Measurement Ultra-High Resolution Optical Coherence Tomography for Imaging the Anterior Segment of the Eye Systems, devices and methods of broadband light sources with tunable spectrum Broadband superluminescent diode–based ultrahigh resolution optical coherence tomography for ophthalmic imaging Quantitative analysis of the intraretinal layers and optic nerve head using ultra-high resolution optical coherence tomography Anterior Segment Biometry during Accommodation Imaged with Ultralong Scan Depth Optical Coherence Tomography Characterization of Soft Contact Lens Fitting Using Ultra-Long Scan Depth Optical Coherence Tomography Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography Evaluation of Age-related Skin Changes and Instrument Reliability Using Clinical Probe Measurements and Imaging Modalities HP-OCT™ wins Victorian AEEA award – nominated for Sir William Hudson award