1. Articles from t. c. frohman

    1-3 of 3
    1. Cup to disc ratio by optical coherence tomography is abnormal in multiple sclerosis

      Cup to disc ratio by optical coherence tomography is abnormal in multiple sclerosis
      Publication year: 2011Source: Journal of the Neurological Sciences, In Press, Corrected Proof, Available online 11 January 2011S.B., Syc , C.V., Warner , S., Saidha , S.K., Farrell , A., Conger , ... Objective: To identify and characterize cup to disc ratio (CDR) and related optic nerve head abnormalities in multiple sclerosis (MS) using spectral domain optical coherence tomography (OCT). Background: While CDR is routinely assessed by ophthalmologists in the evaluation of glaucoma, CDR and related optic nerve head metrics remain largely unexplored in MS. Design/methods: Cirrus-HD (high density) OCT was used to evaluate average CDR, vertical CDR, optic disc area, optic cup ...
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    2. Retinal architecture predicts pupillary reflex metrics in MS

      Objective To study the relation of retinal nerve fiber layer thinning to clinical and physiologic measures of visual function in patients with MS or neuromyelitis optica and unilateral optic neuropathy.MethodsWe studied a cohort of control subjects (n = 64) and patients (n = 24) with evidence of unilateral thinning of their average retinal nerve fiber layer as measured by optical coherence tomography in order to characterize the relationship between ganglion cell axonal degeneration and its impact upon vision and pupillary light reflex metrics using infrared pupillometry. Results When compared to the normal fellow eye, and with respect to normal subjects’ eyes ...
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    3. Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis.

      Related Articles Retinal Imaging by Laser Polarimetry and Optical Coherence Tomography Evidence of Axonal Degeneration in Multiple Sclerosis. Arch Neurol. 2008 Jul;65(7):924-928 Authors: Zaveri MS, Conger A, Salter A, Frohman TC, Galetta SL, Markowitz CE, Jacobs DA, Cutter GR, Ying GS, Maguire MG, Calabresi PA, Balcer LJ, Frohman EM BACKGROUND: Optical coherence tomography (OCT) and scanning laser polarimetry with variable corneal compensation (GDx) are similar yet provide information on different aspects of retinal nerve fiber layer (RNFL) structure (thickness values similar to histology for OCT vs birefringence of microtubules for GDx). OBJECTIVES: To compare the ability of ...
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    1-3 of 3
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    1. (3 articles) University of Pennsylvania
    2. (3 articles) Johns Hopkins University
    3. (3 articles) UT Southwestern Medical Center
    4. (1 articles) Michigan State University
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