1. Articles from j. de seze

    1-3 of 3
    1. Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

      Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

      Neuromyelitis optica (NMO) is an inflammatory autoimmune disease of the central nervous system that preferentially targets the optic nerves and spinal cord. The clinical presentation may suggest multiple sclerosis (MS), but a highly specific serum autoantibody against the astrocytic water channel aquaporin-4 present in up to 80% of NMO patients enables distinction from MS. Optic neuritis may occur in either condition resulting in neuro-anatomical retinal changes. Optical coherence tomography (OCT) has become a useful tool for analyzing retinal damage both in MS and NMO. Numerous studies showed that optic neuritis in NMO typically results in more severe retinal nerve fiber ...

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    2. Longitudinal follow-up of vision in a neuromyelitis optica cohort

      Longitudinal follow-up of vision in a neuromyelitis optica cohort

      Background: Neuromyelitis optica (NMO) is an inflammatory disease associated with optic neuritis and myelitis. Recently, several studies showed that optical coherence tomography (OCT) could be an interesting method for the evaluation of disease severity; however, to date there are no studies with a longitudinal follow-up of visual function in NMO. The aim of this study was to assess the ability of OCT to evaluate the progression of visual dysfunction in NMO. Patients and methods: A group of 30 NMO patients (thus, 60 eyes), comprised of 20 women and 10 men with a mean age of 43.7 +/− 12.3 years ...

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    3. Optical Coherence Tomography in Neuromyelitis Optica.

      Related Articles Optical Coherence Tomography in Neuromyelitis Optica. Arch Neurol. 2008 Jul;65(7):920-923 Authors: de Seze J, Blanc F, Jeanjean L, Zéphir H, Labauge P, Bouyon M, Ballonzoli L, Castelnovo G, Fleury M, Defoort S, Vermersch P, Speeg C BACKGROUND: Neuromyelitis optica (NMO) is an inflammatory disease with combined features of optic neuritis and myelitis. This pathologic entity may induce severe disability, including visual loss and paraplegia. Other than clinical follow-up, there is no marker for severity of the disease. OBJECTIVES: To evaluate the use of optical coherence tomography (OCT) in NMO and to determine whether ...

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    1-3 of 3
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