1. Articles from Christobel Saunders

    1-3 of 3
    1. Parametric imaging of cancer with optical coherence tomography

      Parametric imaging of cancer with optical coherence tomography
      We present a parametric optical coherence tomography (OCT) technique to improve contrast between malignant and healthy non-neoplastic tissue. The technique incorporates a fully automated method to extract tissue attenuation characteristics. Results are represented visually as a parametric en face image, where the parameter used for contrast is indicative of the relative optical attenuation coefficient of the tissue. We present the first parametric OCT images of human lymph nodes containing malignant cells, and demonstrate improved tissue contrast over en face OCT images.
      Read Full Article
    2. Imaging of Human Lymph Nodes Using Optical Coherence Tomography: Potential for Staging Cancer

      Imaging of Human Lymph Nodes Using Optical Coherence Tomography: Potential for Staging Cancer
      Histologic assessment is the gold standard technique for the identification of metastatic involvement of lymph nodes in malignant disease, but can only be performed ex vivo and often results in the unnecessary excision of healthy lymph nodes, leading to complications such as lymphedema. Optical coherence tomography (OCT) is a high-resolution, near-IR imaging modality capable of visualizing microscopic features within tissue. OCT has the potential to provide in vivo assessment of tissue involvement by cancer. In this morphologic study, we show the capability of OCT to image nodal microarchitecture through an assessment of fresh, unstained ex vivo lymph node samples. Examples ...
      Read Full Article
    3. Mapping Tissue Optical Attenuation to Identify Cancer Using Optical Coherence Tomography

      The lymphatic system is a common route for the spread of cancer and the identification of lymph node metastases is a key task during cancer surgery. This paper demonstrates the use of optical coherence tomography to construct parametric images of lymph nodes. It describes a method to automatically estimate the optical attenuation coefficient of tissue. By mapping the optical attenuation coefficient at each location in the scan, it is possible to construct a parametric image indicating variations in tissue type. The algorithm is applied to ex vivo samples of human axillary lymph nodes and validated against a histological gold standard ...
      Read Full Article
    1-3 of 3
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (3 articles) University of Western Australia
    2. (3 articles) Robert A. McLaughlin
    3. (3 articles) David D. Sampson
    4. (2 articles) Sir Charles Gairdner Hospital
    5. (2 articles) Oregon Health & Science University
    6. (2 articles) Loretta Scolaro
    7. (1 articles) Steven L. Jacques
    8. (1 articles) Kawasaki Medical School
    9. (1 articles) Harbin Medical University
    10. (1 articles) Tianjin University
    11. (1 articles) Bo Yu
  3. Popular Articles

  4. Picture Gallery

    Imaging of Human Lymph Nodes Using Optical Coherence Tomography: Potential for Staging Cancer Parametric imaging of cancer with optical coherence tomography Both speckle reduction and contrast enhancement for optical coherence tomography via sequential optimization in the logarithmic domain based on a refined Retinex model OCT parameters of the optic nerve head and the retina as surrogate markers of brain volume in a normal population, a pilot study Choroidal vessel density in unilateral hyperopic amblyopia using en-face optical coherence tomography Association between food and nutrients intakes and coronary plaque vulnerability in patients with coronary heart disease: An optical coherence tomography study Optical Coherence Tomography based treatment approach for patients with Acute Coronary Syndrome Using OCT Fixation Shift to Assess Eccentric Fixation in Children With Residual Amblyopia Intraretinal microvascular changes after ERM and ILM peeling using SSOCTA Image sensor for spectral-domain optical coherence tomography on a chip Identifying Diabetic Macular Edema and Other Retinal Diseases by Optical Coherence Tomography Image and Multiscale Deep Learning Factors Associated with Changes in Retinal Layers Following Acute Optic Neuritis: A Longitudinal Study Using Optical Coherence Tomography