1. Articles from soon-phaik chee

    1-6 of 6
    1. Role of Optical Coherence Tomography in the Prognosis of Vogt–Koyanagi–Harada Disease

      Role of Optical Coherence Tomography in the Prognosis of Vogt–Koyanagi–Harada Disease

      Purpose : To evaluate the prognostic value of OCT in acute VKH disease Methods : Retrospective series of consecutive VKH patients seen with the first presentation, a minimum follow-up of 1 year and serial OCT imaging. The primary outcome was the clinical activity phase at 1, 2 and 3 years. Results : Among 29 subjects, 7 resolved, 17 became chronic, and 5 developed chronic recurrent VKH. Median RNFL measurement obtained 2 months post-treatment was higher among subjects who developed chronic VKH ( p -value = 0.03) and chronic recurrent disease ( p -value = 0.04). Median CRT 1-week post-treatment was lower among subjects who developed ...

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    2. Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt–Koyanagi–Harada Disease

      Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt–Koyanagi–Harada Disease

      Purpose : To compare enhanced depth imaging (EDI-OCT) and swept source optical coherence tomography (SS-OCT) in assessment of Vogt–Koyanagi–Harada (VKH) disease. Methods : All consecutive VKH patients seen at Singapore National Eye Centre during 2012–2013 were imaged using both modalities. Subfoveal choroidal thickness (SFCT) was measured by one masked trained observer. Results : A total of 137 pairs of scans were obtained from 48 patients. SFCT was more likely to be measurable on SS-OCT than EDI-OCT (112, 81.8%; 84, 61.3%; p <0.001 Fisher’s Exact test). There was good inter-OCT correlation of SFCT when both scans were ...

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    3. The role of enhanced depth imaging optical coherence tomography in chronic Vogt-Koyanagi-Harada disease

      The role of enhanced depth imaging optical coherence tomography in chronic Vogt-Koyanagi-Harada disease

      Aims To determine the role of enhanced depth imaging optical coherence tomography (EDI-OCT) in chronic Vogt-Koyanagi-Harada (VKH) disease. Methods Records of all consecutive patients with VKH seen at the Singapore National Eye Centre were retrospectively reviewed for concurrent EDI-OCT and indocyanine green angiograms (ICGAs) obtained six or more months after disease onset, demographics and duration of disease. The ICGAs were scored based on the following signs: early choroidal stromal vessel hyperfluorescence and leakage, hypofluorescent dark dots, fuzzy vascular pattern of large stromal vessels and disc hyperfluorescence, and correlated with the subfoveal choroidal thickness (SFCT) measured using EDI-OCT. Only images of ...

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    4. Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Vogt-Koyanagi-Harada Disease

      Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Vogt-Koyanagi-Harada Disease

      Objective: To compare enhanced depth imaging optical coherence tomography (EDI-OCT) and swept source OCT (SS-OCT) images in Vogt-Koyanagi-Harada (VKH) disease to determine the agreement of subfoveal choroidal thickness (SFCT) measurements between them. Methods: SFCT of one eye of all consecutive VKH patients seen at the Singapore National Eye Centre during 2012 to 2013 was measured using both modalities by one masked trained observer. Charts were retrospectively reviewed for demographics, duration of disease and phase of disease. The acute phase was defined as being within the first 6 months of onset and the chronic phase any time thereafter. Results: 137 SS-OCT ...

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    5. Anterior Segment Optical Coherence Tomography Evaluation of the Integrity of Clear Corneal Incisions: A Comparison between 2.2-mm and 2.65-mm Main Incisions

      Purpose: To compare wound characteristics and integrity of the 2.2-mm and 2.65-mm clear corneal incisions. Design: Prospective, randomized clinical trial. Methods: Patients undergoing phacoemulsification with lens implant were randomized to receive a 2.2-mm or 2.65-mm temporal clear corneal incision. The incisions were evaluated at 2, 24, and 96 hours for gape and wound architecture using anterior segment optical coherence tomography and for integrity using the Seidel test. Squareness of an incision was calculated (ratio of the incision length to the width). Results There were 30 patients in each group. Both incision sizes were watertight, although a ...
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    6. Foveolitis Associated with Dengue Fever: A Case Series

      Background: Dengue fever (DF), a viral infection caused by dengue virus, is characterized by fever, headache, muscle and joint pains. Approximately 50-100 million people are infected annually. Ocular manifestations during DF are uncommon and include intraretinal hemorrhages and cotton wool spots; manifestations predominantly characterized by foveal involvement have not been described before in DF or any other retinopathies. We describe the clinical features of a series of patients with DF-associated foveolitis. Methods: A retrospective review of patients with maculopathy associated with DF was conducted. Patients found to have a yellow-orange lesion at the fovea, supported by a typical optical coherence ...
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    1-6 of 6
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