1. Articles from Yi Yang

    1-12 of 12
    1. Spectral 3D reconstruction of impressionist oil paintings based on macroscopic OCT imaging

      Spectral 3D reconstruction of impressionist oil paintings based on macroscopic OCT imaging

      Art conservators have adopted optical technologies to improve conservation efforts; laser triangulation, stereophotogrammetry, structured light, laser scanners, and time of flight sensors have been deployed to capture the 3D information of sculptures and architectures. Optical coherence tomography (OCT) has introduced new imaging methods to study the surface features and subsurface structures of delicate cultural heritage objects. However, the field of view of OCT severely limits the scanning area. We present a hybrid scanning platform combined with an effective algorithm for real-time sampling and artifact removal to achieve macroscopic OCT (macro-OCT) imaging and spectral 3D reconstruction of impressionist style oil paintings.

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      Mentions: Yi Yang
    2. Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects

      Optical coherence tomography for non-invasive examination and conservation of cultural heritage objects

      Optical coherence tomography (OCT) has great potential for the examination of oil paintings, particularly for celebrated masterpieces by great artists in history. We developed an OCT system for large field of view (FOV), high definition (HD) imaging of oil paintings. To achieve large FOV, we translated the sample using a pair of high-precision linear motors and performed sequential volumetric imaging on adjacent, non-overlapping regions. Through 3D OCT imaging, the surface terrain and subsurface microarchitecture of the paintings have been characterized and visualized.

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    3. High-definition optical coherence tomography imaging for noninvasive examination of heritage works

      High-definition optical coherence tomography imaging for noninvasive examination of heritage works

      Cultural heritage works, such as ancient murals and historical paintings, are examined routinely for the purpose of conservation. Previous works have applied optical coherence tomography (OCT), which is a three-dimensional (3D) microscopic imaging modality in the field of heritage works conservation. The data acquired by OCT provides both 3D surface information of the object and structure information underneath the surface. Therefore, cross-sectional information on the object can be utilized to study layer structure of the painting and brush stroke techniques used by the artist. However, as demonstrated in previous studies, OCT has limited capability in high-definition (HD) examination of paintings ...

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    4. A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography

      A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography

      Wang, Tianheng; Yang, Yi; Zhu, QuingIn this paper, a logistic prediction model is introduced to characterize the ovarian tissue. A new parameter, the phase retardation rate, was extracted from phase images of polarization-sensitive optical coherence tomography (PS-OCT). Statistical significance of this parameter between normal and ... [Biomed. Opt. Express 4, 772-777 (2013)]

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    5. Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography

      Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography

      Angle-resolved optical scattering properties of ovarian tissue, on different optical coherence tomography (OCT) imaging planes, were quantitatively measured by fitting the compounded OCT A-lines into a single scattering model. Higher cross correlation value of angle-resolved scattering coefficients between different OCT imaging planes was found in normal ovaries than was present in malignant ovaries. The mean cross correlation coefficient (MCC) was introduced in this pilot study to characterize and differentiate normal, n=6 , and malignant, n=4 , ovaries. A specificity of 100 percent and a sensitivity of 100 percent were achieved by setting MCC threshold at 0.6. Collagen properties, within ...

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    6. Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images

      Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images

      Optical scattering coefficient from ex-vivo unfixed normal and malignant ovarian tissue was quantitatively extracted by fitting optical coherence tomography (OCT) A-line signals to a single scattering model. 1097 average A-line measurements at a wavelength of 1310nm were performed at 108 sites obtained from 18 ovaries. The average scattering coefficient obtained from normal group consisted of 833 measurements from 88 sites was 2.41 mm-1 (±0.59), while the average coefficient obtained from malignant group consisted of 264 measurements from 20 sites was 1.55 mm-1 (±0.46). Using a threshold of 2 mm-1 for each ovary, a sensitivity of 100 ...

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    7. Feature Of The Week 10/23/11: Hybrid Intraoperative Probe Based on OCT and Positron Detection for Ovarian Cancer Detection

      Feature Of The Week 10/23/11: Hybrid Intraoperative Probe Based on OCT and Positron Detection for Ovarian Cancer Detection
      Multi-modality imaging involving OCT and one or more additional imaging technologies continues to show very promising results for increasing the diagnostic and interventional guidance capability of biomedical imaging probes. These synergistic effects have been published in numerous papers over the past year. This includes OCT in combination with fluorescence, Raman, NIR, ultrasound, and other technologies. Such approaches have the obvious disadvantage of increasing the cost and complexity of the imaging system but often that burden is offset by significantly increased performance. Recently a group from the University of Connecticut published a paper on a hybrid intraoperative probe that used OCT ...
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    8. Optical scattering coefficient estimated by optical coherence tomography correlates with collagen content in ovarian tissue

      Optical scattering coefficient estimated by optical coherence tomography correlates with collagen content in ovarian tissue
      Optical scattering coefficient from ex vivo unfixed normal and malignant ovarian tissue was quantitatively extracted by fitting optical coherence tomography (OCT) A-line signals to a single scattering model. 1097 average A-line measurements at a wavelength of 1310 nm were performed at 108 sites obtained from 18 ovaries. The average scattering coefficient obtained from the normal tissue group consisted of 833 measurements from 88 sites was 2.41 mm−1 (±0.59), while the average coefficient obtained from the malignant tissue group consisted of 264 measurements from 20 sites was 1.55 mm−1 (±0.46). The malignant ovarian tissue showed ...
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    9. Integrated optical coherence tomography, ultrasound and photoacoustic imaging for ovarian tissue characterization

      Integrated optical coherence tomography, ultrasound and photoacoustic imaging for ovarian tissue characterization
      Ovarian cancer has the lowest survival rate of the gynecologic cancers because it is predominantly diagnosed in Stages III or IV due to the lack of reliable symptoms, as well as the lack of efficacious screening techniques. Detection before the malignancy spreads or at the early stage would greatly improve the survival and benefit patient health. In this report, we present an integrated optical coherence tomography (OCT), ultrasound (US) and photoacoustic imaging (PAI) prototype endoscopy system for ovarian tissue characterization. The overall diameter of the prototype endoscope is 5 mm which is suitable for insertion through a standard 5-12.5mm ...
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    10. 3D imaging of dental hard tissues with Fourier domain optical coherence tomography

      3D imaging of dental hard tissues with Fourier domain optical coherence tomography
      A fiber optical coherence tomography (OCT) probe is used for three dimensional dental imaging. The probe has a lightweight miniaturized design with a size of a pen to facilitate clinic in vivo diagnostics. The probe is interfaced with a swept-source / Fourier domain optical coherence tomography at 20K axial scanning rate. The tooth samples were scanned from occlusal, buccal, lingual, mesial, and distal orientations. Three dimensional imaging covers tooth surface area up to 10 mm x 10 mm with a depth about 5 mm, where a majority of caries affection occurs. OCT image provides better resolution and contrast compared to gold ...
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    11. Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization

      Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization
      Ovarian cancer has the lowest survival rate of the gynecologic cancers because it is predominantly diagnosed in the late stages due to the lack of reliable symptoms and efficacious screening techniques. A novel hybrid intraoperative probe has been developed and evaluated for its potential role in detecting and characterizing ovarian tissue. The hybrid intraoperative dual-modality device consists of multiple scintillating fibers and an optical coherence tomography imaging probe for simultaneously mapping the local activities of 18F-FDG uptake and imaging of local morphological changes of the ovary. Ten patients were recruited to the study and a total of 18 normal, abnormal ...
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    12. A prototype hybrid intraoperative probe for ovarian cancer detection

      A prototype hybrid intraoperative probe for ovarian cancer detection
      A novel prototype intraoperative system combining positron detection and optical coherence tomography (OCT) imaging has been developed for early ovarian cancer detection. The probe employs eight plastic scintillating fiber tips for preferential detection of local positron activity surrounding a central scanning OCT fiber providing volumetric imaging of tissue structure in regions of high radiotracer uptake. Characterization measurements of positron sensitivity, spatial response, and position mapping are presented for Tl204/Cs137 sources as well as 18F-FDG. In conjunction with co-registered frequency domain OCT measurements the results demonstrate the potential for a miniaturized laparoscopic probe offering simultaneous functional localization and structural imaging ...
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    1-12 of 12
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  2. Topics in the News

    1. (12 articles) Yi Yang
    2. (9 articles) University of Connecticut
    3. (9 articles) Quing Zhu
    4. (8 articles) Tianheng Wang
    5. (7 articles) Molly Brewer
    6. (5 articles) Nrusingh C. Biswal
    7. (5 articles) Melinda Sanders
    8. (3 articles) Patrick D. Kumavor
    9. (2 articles) Boston University
    10. (2 articles) Yueli L. Chen
    11. (1 articles) Jikei University School of Medicine
    12. (1 articles) Macquarie University
    13. (1 articles) Medical University of Vienna
    14. (1 articles) University of Florence
    15. (1 articles) National Institutes of Health
    16. (1 articles) Beth Israel Deaconess Medical Center
    17. (1 articles) Giacomo Savini
    18. (1 articles) Bernhard Baumann
    19. (1 articles) Antonia Lichtenegger
    20. (1 articles) Movu
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    A prototype hybrid intraoperative probe for ovarian cancer detection Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization 3D imaging of dental hard tissues with Fourier domain optical coherence tomography Integrated optical coherence tomography, ultrasound and photoacoustic imaging for ovarian tissue characterization Optical scattering coefficient estimated by optical coherence tomography correlates with collagen content in ovarian tissue Feature Of The Week 10/23/11: Hybrid Intraoperative Probe Based on OCT and Positron Detection for Ovarian Cancer Detection Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images Quantitative analysis of angle-resolved scattering properties of ovarian tissue using optical coherence tomography A three-parameter logistic model to characterize ovarian tissue using polarization-sensitive optical coherence tomography High-definition optical coherence tomography imaging for noninvasive examination of heritage works Heterogeneity of Neointimal Healing Following Biodegradable-polymer Drug-Eluting Coronary Stent Implantation Swept-source and multimodal OCT technologies offer clinical advantages