1. Articles from jakub j. kaluzny

    1-7 of 7
    1. Quantitative Assessment of Retinal Thickness and Vessel Density Using Optical Coherence Tomography Angiography in Patients with Alzheimer’s Disease and Glaucoma

      Quantitative Assessment of Retinal Thickness and Vessel Density Using Optical Coherence Tomography Angiography in Patients with Alzheimer’s Disease and Glaucoma

      Background Retinal imaging using optical coherence tomography (OCT) and OCT angiography (OCTA) may serve as an alternative approach to monitoring and diagnosing neurodegenerative diseases such as Alzheimer's disease (AD) and primary open-angle glaucoma (POAG). In this study, we performed direct comparisons of retinal vessel density with the thickness of inner retinal layer (IRL) and outer retinal layer (ORL) in patients with AD and POAG. Methods In this cross-sectional study, we analyzed data from 48 eyes of healthy control (HC) participants, 71 eyes of POAG patients, and 49 eyes of AD patients with confirmed presence of fibrillar brain amyloid on ...

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    2. Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma

      Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma

      Purpose To evaluate the correlation between retinal sensitivity in microperimetry (MP) with vessel density (VD) using optical coherence tomography angiography (OCTA) in primary open-angle glaucoma (POAG). Methods We enrolled 30 participants (52 eyes) with POAG and 15 participants (23 eyes) in the healthy control group. All participants were examined for retinal structure using OCTA to assess VD and Spectral domain OCT (SD-OCT) to assess ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer (pRNFL) thickness. Retinal sensitivity was tested with MP and standard automatic perimetry (SAP). Results The VD in moderate/severe POAG was lower than that in mild ...

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    3. Comparison of Retinal Microvasculature in Patients With Alzheimer's Disease and Primary Open-Angle Glaucoma by Optical Coherence Tomography Angiography

      Comparison of Retinal Microvasculature in Patients With Alzheimer's Disease and Primary Open-Angle Glaucoma by Optical Coherence Tomography Angiography

      Purpose : Comparison of retinal microvasculature within the macula and the optic nerve head in the eyes of patients with Alzheimer's disease (AD), primary open-angle glaucoma (POAG), and in a healthy control (HC) group, using optical coherence tomography angiography (OCTA). Methods : In this cross-sectional study, 27 patients with AD, 27 with POAG, and 27 healthy controls were enrolled. The Mini-Mental State Examination test was used to assess cognitive function. Ophthalmic examination included OCTA, which was used for the imaging of vascular flow within the layer of radial peripapillary capillaries (RPCs), and also in the superficial vascular plexus (SVP) and deep ...

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    4. Intereye asymmetry of optic nerve head parameters and retinal nerve fibre layer thickness in patients with open angle glaucoma detected by spectral domain optical coherence tomography

      Intereye asymmetry of optic nerve head parameters and retinal nerve fibre layer thickness in patients with open angle glaucoma detected by spectral domain optical coherence tomography

      INTRODUCTION. The aim of the study is to evaluate intereye asymmetry of optic nerve head (ONH) parameters and the circumpapillary retinal nerve fibre layer (cpRNFL) thickness in patients with primary open angle glaucoma (POAG). MATERIA LS AND METHODS. The study included 44 patients with POAG in both eyes, 48 binocular glaucoma suspects, and 75 individuals with two healthy eyes. A mixed group of 20 patients had only one eye that met the criteria for POAG. We evaluated the differences between right and left eyes and absolute intereye asymmetry for the individual ONH parameters and cpRNFL thickness, measured by spectral domain ...

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    5. Tear Meniscus Measurement by Spectral Optical Coherence Tomography

      Tear Meniscus Measurement by Spectral Optical Coherence Tomography

      Purpose. To evaluate the use of lower tear meniscus measurements obtained with anterior segment Spectral Optical Coherence Tomography (OCT) in quantitative tear evaluation and diagnosis of dry eye syndrome. To verify sensitivity and specificity of different tear meniscus parameters in diagnosis of dry eye syndrome. Methods. A total of 111 eyes in consecutive patients, mean age 34.35 years (SD, 11.17), were enrolled. Each patient completed a standard Ocular Surface Disease Index questionnaire and general ophthalmic examination. Lower tear meniscus was evaluated using Spectral OCT (RTVue, Optovue) with cornea-anterior segment lens short. Three parameters were measured: tear meniscus cross-section ...

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    6. Analysis of the Outer Retina Reconstructed by High-resolution, Three-dimensional Spectral Domain Optical Coherence Tomography

      BACKGROUND AND OBJECTIVE A retrospective cross-sectional study was conducted to demonstrate an analysis of an outer retinal layer reconstructed by the three-dimensional and high-speed spectral domain optical coherence tomography (SD-OCT) instrument. PATIENTS AND METHODS New measurement protocols for SD-OCT and methods of analysis and visualization of the individual segmented retinal layer reconstructed by SD-OCT were proposed. Three contour maps representing mutual distances between the basal part of the retinal pigment epithelium, the junction between the inner and outer segments of photoreceptors, and a reference contour representing the shape of a healthy retina were introduced. RESULTS The analysis of the outer ...
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    7. Correlation of Spectral Optical Coherence Tomography with Fluorescein and Indocyanine Green Angiography in Multiple Evanescent White Dot Syndrome

      Aims: To determine spatial location of lesions in Multiple Evanescent White Dot Syndrome (MEWDS) with the aid of spectral optical coherence topography (SOCT), fluorescein angiography (FA) and indocyanine green angiography (ICGA). Methods: A novel method of three-dimensional SOCT data analysis called reflectivity maps was introduced. The reflectivity maps display the distribution of a back-reflected intensity taken only from individual retinal layers located at specific distance from the reference plane. Reflectivity maps of the inner retina, the junction between photoreceptor inner and outer segments (IS/OS), retinal pigment epithelium and choroid of the patient with MEWDS were created and correlated with ...
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    1-7 of 7
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    Tear Meniscus Measurement by Spectral Optical Coherence Tomography Intereye asymmetry of optic nerve head parameters and retinal nerve fibre layer thickness in patients with open angle glaucoma detected by spectral domain optical coherence tomography Comparison of Retinal Microvasculature in Patients With Alzheimer's Disease and Primary Open-Angle Glaucoma by Optical Coherence Tomography Angiography Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma Quantitative Assessment of Retinal Thickness and Vessel Density Using Optical Coherence Tomography Angiography in Patients with Alzheimer’s Disease and Glaucoma Novel Optical Coherence Tomography Parameters as Prognostic Factors for Stage 3 Epiretinal Membranes En-face OCT and OCT angiography analysis of macular choroidal macrovessel Three-dimensional live imaging of bovine embryos by optical coherence tomography Comparison of Subfoveal Choroidal Thickness and Retinal Nerve Fiber Layer Thickness in Patients with Coronary Slow Flow Phenomenon and Microvascular Angina: Optical Coherence Tomography based study Optical Coherence Tomography of the Orbit Through a Staphyloma: A View of Tenon's Capsule, Orbital Fat, and Inferior Oblique Muscle Line field Fourier domain optical coherence tomography based on a spatial light modulator Post-doctoral Scholar Position in OCT Endoscopy at the University of North Carolina at Chapel Hill