1. Articles from Ying Jin

    1-5 of 5
    1. Monitoring skin trauma healing in mice using second-harmonic generation combined with optical coherence tomography

      Monitoring skin trauma healing in mice using second-harmonic generation combined with optical coherence tomography

      Convenient methods for rapidly evaluating wound healing could help clinicians to select effective treatment measures for patients within an appropriate time frame. In this study, we explored the use of second-harmonic generation (SHG) combined with optical coherence tomography (OCT) to monitor the healing state of wounds, including the macromorphology and optical signal characteristics of regenerated tissue. Wounds were imaged and monitored using OCT and SHG on healing days 3, 5, 7, 14, 21 and 28. The accumulation and maturation of newly formed collagen during the healing process was detected using SHG in real time. Additionally, changes in the OCT signal ...

      Read Full Article
    2. Assessment of laser-induced acceleration effects in optical clearing of in vivo human skin by optical coherence tomography

      Assessment of laser-induced acceleration effects in optical clearing of in vivo human skin by optical coherence tomography

      Laser irradiation is considered to be a promising innovative technology which has been developed in an attempt to increase transdermal drug delivery. In this study, a near-infrared CW diode laser (785 nm) was applied to increase permeability of glycerol solutions in human skin in vivo and improve the optical clearing efficacy. Results show that for both 15%v/v and 30%v/v glycerol, the permeability coefficient increased significantly if the detected area of the skin tissue was treated with laser irradiation before optical clearing agents (OCAs) were applied. This study based on optical coherence tomography imaging technique and optical ...

      Read Full Article
    3. Monitoring skin photodamage using quantitative optical coherence tomography

      Monitoring skin photodamage using quantitative optical coherence tomography
      Noninvasive, real-time imaging technology assists UV light therapy of skin diseases and facilitates reduction of the associated photodamage. In clinical medicine, 8-methoxypsoralen (8-MOP) combined with ultraviolet A (UVA; 320–400nm) (PUVA) therapy is an effective and widely used treatment for several types of dermatose, including psoriasis, mycosis fungoides, and vitiligo. However, many studies have shown that PUVA has both potent mutagenic and carcinogenic effects and also immunosuppressive consequences. The latter can allow tumor development or changes to the immune function in both immuno-suppressed and healthy individuals.1,2 Long-term PUVA therapy significantly increases the risk of skin-cancer development.3,4
      Read Full Article
    4. Quantitative analysis on PUVA-induced skin photodamages using optical coherence tomography

      Psoralen plus ultraviolet A radiation (PUVA) therapy is a very important clinical treatment of skin diseases such as vitiligo and psoriasis, but associated with an increased risk of skin photodamages especially photoaging. Since skin biopsy alters the original skin morphology and always requires an iatrogenic trauma, optical coherence tomography (OCT) appears to be a promising technique to study skin damage in vivo. In this study, the Balb/c mice had 8-methoxypsralen (8-MOP) treatment prior to UVA radiation was used as PUVA-induced photo-damaged modal. The OCT imaging of photo-damaged group (modal) and normal group (control) in vivo was obtained of mice ...
      Read Full Article
    5. Assessment of the effect of narrowband UVB and broadband UVB on mice skin using optical coherence tomography

      Ultraviolet B (UVB) has been used in dermatological phototherapy widely. Narrowband UVB (NB-UVB), with a peak at 311nm, is considered more effective than broadband UVB (BB-UVB). However, the safety of NB-UVB is controversial. Optical coherence tomography (OCT), a novel, non-invasive and depth-resolved imaging technology, is a useful tool for detection of the skin structure in vivo. This study assessed the effect of NB-UVB and BB-UVB on the skin using OCT for the first time. In this study, Balb/c mouse model was surveyed by an OCT system with 1310 nm central wavelength. The two UVB sources were applied on mice ...
      Read Full Article
    1-5 of 5
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (2 articles) Boston University
    2. (2 articles) Massachusetts General Hospital
    3. (1 articles) South China Normal University
    4. (1 articles) Harvard University
    5. (1 articles) University of Maryland
    6. (1 articles) The Chinese University of Hong Kong
    7. (1 articles) Cleveland Clinic
    8. (1 articles) Duke University
    9. (1 articles) University of Queensland
    10. (1 articles) Massachusetts Institute of Technology
    11. (1 articles) FDA
  3. Popular Articles

  4. Picture Gallery

    Monitoring skin photodamage using quantitative optical coherence tomography Assessment of laser-induced acceleration effects in optical clearing of in vivo human skin by optical coherence tomography Monitoring skin trauma healing in mice using second-harmonic generation combined with optical coherence tomography A novel algorithm for multiplicative speckle noise reduction in ex vivo human brain OCT images Volumetric characterization of microvasculature in ex vivo human brain samples by serial sectioning optical coherence tomography Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide Retinal changes in bipolar disorder as an endophenotype candidate: Comparison of OCT-detected retinal changes in patients, siblings, and healthy controls Intraoperative optical coherence tomography guided 25G micro-amount trajectory vitrectomy for the treatment of penetrating ocular injury caused by a foreign body in the right eye: A case study Optical coherence tomography angiography reveals paradoxically decreasing choroidal thickness & increasing blood flow in remitting Vogt Koyanagi Harada syndrome A comparison of macular ganglion cell and retinal nerve fibre layer optical coherence tomographic parameters as predictors of visual outcomes of surgery for pituitary tumours Fundus Changes Evaluated by OCTA in Patients With Cerebral Small Vessel Disease and Their Correlations: A Cross-Sectional Study Optical Coherence Tomography Combined with Fluorescein Fundus Angiography under Intelligent Algorithm to Evaluate the Clinical Efficacy of Ranibizumab Combined with Panretinal Photocoagulation in the Treatment of Macular Edema of Diabetic Retinopathy Pati