1. Articles from Robert A. Huber

    1-9 of 9
    1. A 4-D OCT Engine with 1 GVoxel/s

      A 4-D OCT Engine with 1 GVoxel/s

      Optical coherence tomography (OCT) is a depth-resolved imaging modality that provides micrometer-scale cross-sectional and 3-D information on the scattering properties of biological samples. 1 Video rate real-time 3-D volumetric OCT (4-D-OCT) could generate a new class of optical tools in clinical practice, like surgical guidance. 2 This challenge requires us to combine a high-speed OCT imaging setup, ultrafast data acquisition and adequate real-time data processing to process and visualize the vast amount of data. Although 4-D-OCT has long been a dream for researchers, only a few groups have successfully implemented 4-D volumetric OCT imaging with real-time visualization—usually with low ...

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    2. Fourier domain mode locking: method and apparatus for control and improved performance

      Fourier domain mode locking: method and apparatus for control and improved performance

      A control system for improving and stabilizing Fourier domain mode locking (FDML) operation. The control system may also provide regulation of FDML operational parameters such as filter tuning, laser gain, polarization, polarization chromaticity, elliptical polarization retardance, and/or dispersion. The control system may be located internal to or external from the FDML laser cavity.

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    3. Chromatic polarization effects of swept waveforms in FDML lasers and fiber spools

      Chromatic polarization effects of swept waveforms in FDML lasers and fiber spools

      We present detailed investigations of chromatic polarization effects, caused by fiber spools used in FDML lasers and buffering spools for rapidly wavelength swept lasers. We introduce a novel wavelength swept FDML laser source, specially tailored for polarization sensitive optical coherence tomography (OCT) which switches between two different linear polarization states separated by 45°, i.e. 90° on the Poincaré sphere. The polarization maintaining laser cavity itself generates a stable linear polarization state and uses an external buffering technique in order to provide alternating polarization states for successive wavelength sweeps. The design of the setup is based on a comprehensive analysis ...

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    4. Extended coherence length Fourier domain mode locked lasers at 1310 nm

      Extended coherence length Fourier domain mode locked lasers at 1310 nm
      Fourier domain mode locked (FDML) lasers are excellent tunable laser sources for frequency domain optical coherence tomography (FD-OCT) systems due to their combination of high sweep rates, large tuning ranges, and high output powers. However, conventional FDML lasers provide coherence lengths of only 4–10 mm, limiting their use in demanding applications such as intravascular OCT where coherence lengths of >20 mm are required for optimal imaging of large blood vessels. Furthermore, like most swept lasers, conventional FDML lasers produce only one useable sweep direction per tunable filter drive cycle, halving the effective sweep rate of the laser compared to ...
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    5. Feature Of The Week 9/4/11: Researchers at Ludwig-Maximilians University Continue to Blaze Trails Developing High Performance Swept Source OCT Technology and Its Application in Medical Imaging

      Feature Of The Week 9/4/11: Researchers at Ludwig-Maximilians University Continue to Blaze Trails Developing High Performance Swept Source OCT Technology and Its Application in Medical Imaging
      Researchers at Ludwig-Maximilians University continue to blaze trails in their work developing high performance swept source optical coherence tomography technology and the application of high speed frequency tuned sources in medical imaging. The Fourier-domain mode locked laser (FDML) together with tapped-delay line sweep-rate multipliers, light delivery and calibration optics, novel frame averaging and sampling techniques, wide FOV scanning technology, and high speed signal processing and visualization technology are impressive and will clearly have a significant impact on future medical imaging systems and ultimately patient care. Below is a presentation on some of their work entitled “(Multi-) MHz FDML OCT: Retinal ...
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    6. Feature Of The Week 9/5/10: Record Breaking OCT Volumetric Image Acquisition Rates by Researchers at Ludwig Maximilians University

      Feature Of The Week 9/5/10: Record Breaking OCT Volumetric Image Acquisition Rates by Researchers at Ludwig Maximilians University
      Feature Of The Week 9/5/10: As the 2010 academic years begins OCT News will resume its “Feature Of The Week” section. This year starts with an exciting submission by Dr. Robert Huber’s research group at Ludwig-Maximilians-Universität in Munich on record breaking OCT volumetric data set acquisition rates that were hard to imaging just a few years ago.Currently there is an ongoing debate about the optimum imaging speed of Optical Coherence Tomography (OCT) systems, considering the tradeoff between speed and image quality. Huge efforts have been made to push the imaging speed of OCT. This includes the ...
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    7. Fourier Domain Mode Locking (FDML): Wavelength Swept Lasers for Ultrahigh Speed Optical Coherence Tomography

      Optical coherence tomography (OCT) is a novel, depth resolved biomedical imaging technique, providing highresolution, cross-sectional and three-dimensional images of tissue microstructure. The application of OCT systems based on rapidly wavelength swept, narrow band light sources, referred to as “swept source OCT” or “optical frequency domain imaging”, offers several potential advantages compared to high speed OCT systems based on fast spectrometers. The advent of Fourier domain mode locked (FDML) lasers as light sources for swept source OCT enabled high imaging speeds of up to 370.000 lines or A-scans per second, combined with good phase stability and long ranging depths. In ...
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    8. Feature Of The Week 12/6/09: Cascaded Wavelength Swept Amplified Spontaneous Emission Source for Optical Coherence Tomography

      Feature Of The Week 12/6/09: Cascaded Wavelength Swept Amplified Spontaneous Emission Source for Optical Coherence Tomography
      Feature Of The Week 12/6/09: Due to increasing interest in Optical Coherence Tomography (OCT) using wavelength swept lasers (SS-OCT), huge efforts have been made by both research and commercial organizations around the world to push the performance of such sources and with it OCT system capabilities. This includes sweep repetition rate, power, new wavelengths, coherence length, and more. One of the drawbacks of standard wavelength-swept lasers is the fact that lasing has to build up from amplified spontaneous emission repetitively within several roundtrips of the light, limiting the maximum achievable sweep speed. Dr. Robert Huber and other researchers ...
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    9. High-resolution optical coherence tomography imaging of the living kidney

      Optical coherence tomography (OCT) is a rapidly emerging imaging modality that can provide non-invasive, cross-sectional, high-resolution images of tissue morphology in situ and in real-time. In the present series of studies, we used a high-speed OCT imaging system equipped with a frequency-swept laser light source (1.3 m wavelength) to study living kidneys in situ. Adult, male Munich–Wistar rats were anesthetized, a laparotomy was performed and the living kidneys were exposed for in situ observation. We observed the kidneys prior to, during and following exposure to renal ischemia induced by clamping the renal artery. The effects of intravenous mannitol ...
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    1-9 of 9
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  2. Topics in the News

    1. (9 articles) Robert A. Huber
    2. (8 articles) Ludwig Maximilian University of Munich
    3. (6 articles) Wolfgang Wieser
    4. (4 articles) Benjamin R. Biedermann
    5. (4 articles) Christoph M. Eigenwillig
    6. (3 articles) Desmond C. Adler
    7. (3 articles) Thomas Klein
    8. (2 articles) Massachusetts Institute of Technology
    9. (2 articles) Tom Pfeiffer
    10. (2 articles) James G. Fujimoto
    11. (1 articles) Institute of Applied Physics
    12. (1 articles) Medical University of Vienna
    13. (1 articles) Kyungpook National University
    14. (1 articles) Singapore Eye Research Institute
    15. (1 articles) University of Western Australia
    16. (1 articles) Stefan G. Sacu
    17. (1 articles) Brendan F. Kennedy
    18. (1 articles) Yongyang Huang
    19. (1 articles) Jeehyun Kim
    20. (1 articles) Ursula Schmidt-Erfurth
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    Feature Of The Week 12/6/09: Cascaded Wavelength Swept Amplified Spontaneous Emission Source for Optical Coherence Tomography Feature Of The Week 9/5/10: Record Breaking OCT Volumetric Image Acquisition Rates by Researchers at Ludwig Maximilians University Feature Of The Week 9/4/11: Researchers at Ludwig-Maximilians University Continue to Blaze Trails Developing High Performance Swept Source OCT Technology and Its Application in Medical Imaging Extended coherence length Fourier domain mode locked lasers at 1310 nm Chromatic polarization effects of swept waveforms in FDML lasers and fiber spools Fourier domain mode locking: method and apparatus for control and improved performance A 4-D OCT Engine with 1 GVoxel/s Full-range space-division multiplexing optical coherence tomography angiography Measuring 3D Optic Nerve Head Deformations using Digital Volume Correlation of in vivo Optical Coherence Tomography Data (Thesis) Optical coherence tomography for characterization of nanocomposite materials (Thesis) In Vivo Corneal Microstructural Changes in Herpetic Stromal Keratitis: A Spectral-Domain Optical Coherence Tomography Analysis Non-invasive optical screening of Streptococcus Pneumonia based inflammatory changes of the tympanic membrane and mastoid mucosa in guinea pig otitis media using optical coherence tomography