1. Articles from Ron Margolis

    1-6 of 6
    1. Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding

      Objective  To describe tubular structures found in the outer retina seen in a variety of retinal disorders. Methods  Sixty-nine eyes of 63 patients were examined with spectral-domain optical coherence tomography. Optical coherence tomography C-scans were correlated with their corresponding B-scans. The prevalence, number, size, and shape of the tubular structures were determined. Results  Branching tubules were identified in the outer retina of 54 patients with age-related macular degeneration and in 9 patients with other diagnoses. The tubules appeared as round or ovoid hyporeflective spaces with hyperreflective borders on the B-scans, measuring 40 to 140 µm high and 40 to 2260 ...
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    2. Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding

      Outer Retinal Tubulation: A Novel Optical Coherence Tomography Finding

      Objective To describe tubular structures found in the outer retina seen in a variety of retinal disorders. Methods Sixty-nine eyes of 63 patients were examined with spectral-domain optical coherence tomography. Optical coherence tomography C-scans were correlated with their corresponding B-scans. The prevalence, number, size, and shape of the tubular structures were determined. Results Branching tubules were identified in the outer retina of 54 patients with age-related macular degeneration and in 9 patients with other diagnoses. The tubules appeared as round or ovoid hyporeflective spaces with hyperreflective borders on the B-scans, measuring 40 to 140 Μm high and 40 to 2260 ...

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    3. Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Central Serous Chorioretinopathy

      Purpose: The purpose of the study was to evaluate the choroidal thickness in patients with central serous chorioretinopathy, a disease attributed to increased choroidal vascular hyperpermeability. Methods: Patients with central serous chorioretinopathy underwent enhanced depth imaging spectral-domain optical coherence tomography, which was obtained by positioning a spectral-domain optical coherence tomography device close enough to the eye to acquire an inverted image. Seven sections, each comprising 100 averaged scans, were obtained within a 5° × 30° rectangle to encompass the macula. The subfoveal choroidal thickness was measured from the outer border of the retinal pigment epithelium to the inner scleral border. Results ...
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    4. Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Highly Myopic Eyes

      Purpose: To measure macular choroidal thickness (CT) in highly myopic eyes using enhanced depth imaging optical coherence tomography (OCT).Design: Retrospective, observational case series.Methods: Enhanced depth imaging OCT images were obtained in highly myopic eyes (≥6 diopters [D]). Images of CT were obtained by positioning a spectral-domain OCT device close enough to the eye to acquire an inverted image. CT was measured from the outer border of the retinal pigment epithelium to the inner scleral border at 1000-μm intervals of a horizontal section from 3 mm temporal to the fovea to 3 mm nasal to the fovea. Statistical analysis ...
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    5. A Pilot Study of Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Normal Eyes

      Purpose: To measure macular choroidal thickness in normal eyes at different points using enhanced depth imaging (EDI) optical coherence tomography (OCT) and to evaluate the association of choroidal thickness and age.Design: Retrospective, observational case series.Methods: EDI OCT images were obtained in patients without significant retinal or choroidal pathologic features. The images were obtained by positioning a spectral-domain OCT device close enough to the eye to acquire an inverted image. Seven sections were obtained within a 5 × 30-degree area centered at the fovea, with 100 scans averaged for each section. The choroid was measured from the outer border of ...
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    6. Diagnostic Modalities in Diabetic Retinopathy (Book Chapter)

      Diagnostic Modalities in Diabetic Retinopathy (Book Chapter)
      In addition to ophthalmologic examination and retinal fundus photography, diagnostic modalities including fluorescein angiography (FA) and optical coherence tomography (OCT) currently play important roles in the evaluation of patients with diabetic retin- opathy (DR). Fluorescein angiography has been a major diagnostic procedure in the clinical evaluation of DR for several decades. This chapter will review the principles and methodology underlying fluorescein angiography, as well as its specific application to the evaluation of diabetic retinopathy and especially retinal vascular permeability. Although fluorescein angiography provides valuable anatomic and functional information pertaining to the retinal vasculature, it does not provide ultrastructural anatomic detail ...
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    1-6 of 6
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    1. (5 articles) Richard F. Spaide
    2. (2 articles) LuEsther T. Mertz Retinal Research Center
    3. (1 articles) University Hospital Zurich
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    5. (1 articles) Cleveland Clinic
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