Distance From the Coronary Ostium as a Predictor of Vulnerable Plaque Morphology; An In-vivo Optical Coherence Tomography Study
Background: Plaque morphology predicts its vulnerability to cause acute coronary events; most of which occur due to disruption of lipid-rich thin-cap fibroatheroma (TCFA). Observational studies show that lesions causing acute events are clustered in the proximal coronary artery segments.
Aim: To evaluate whether the location of plaque in the coronary vessel is predictive of vulnerable plaque morphology identified by optical coherence tomography (OCT).
Methods: OCT was performed in patients undergoing catheterization. Plaque distance (PD) from the ostium was measured with angiography using standardised projections. A cut point derived from the median PD was used to define proximal and distal coronary ...
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