1. Articles from Atsuo Tomidokoro

    1-14 of 14
    1. Iridotrabecular contact observed using anterior segment three-dimensional OCT in eyes with a shallow peripheral anterior chamber

      Iridotrabecular contact observed using anterior segment three-dimensional OCT in eyes with a shallow peripheral anterior chamber

      Purpose: To evaluate the prevalence and range of iridotrabecular contact (ITC) in eyes with a shallow peripheral anterior chamber (AC) by using anterior segment swept-source optical coherence tomography (AS-SS-OCT) and to compare the results with those obtained with ultrasound biomicroscopy (UBM) and gonioscopy. Methods: Forty-three shallow peripheral AC eyes in 43 consecutive patients underwent gonioscopy. Cross-sectional images throughout the angle circumference (i.e., 360 degrees) were obtained with AS-SS-OCT (SS-1000 CASIA, Tomey) and those of the peripheral AC at the 3, 6, 9, and 12 o'clock positions were obtained with UBM (UD-1000, Tomey). Results: ITC evaluated with AS-SS-OCT included ...

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    2. Circle and Grid-wise Analyses of Peripapillary Nerve Fiber Layers by Spectral Domain Optical Coherence Tomography in Early Stage Glaucoma

      Circle and Grid-wise Analyses of Peripapillary Nerve Fiber Layers by Spectral Domain Optical Coherence Tomography in Early Stage Glaucoma

      PURPOSE. To study diagnostic performances of circle and grid-wise analyses of peripapillary retinal nerve fiber layer thickness (RNFLT) using spectral domain optical coherence tomography (SD-OCT) in early stage glaucoma. METHODS. Eighty-nine open-angle glaucoma (OAG) eyes (mean deviation, -2.5 ± 1.8 dB) and 89 age-matched normal eyes were studied. Peripapillary RNFLT was analyzed using SD-OCT raster scan in a 6.0 × 6.0 mm area. Averaged RNFLT was calculated over 0.1 × 0.1, 0.21 × 0.21, or 0.42 × 0.42 mm grids in the peripapillary area (grid method), or arcuate sector areas between 2.8 and 4 ...

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    3. Fundus oculi observation device, ophthalmologic image processing device, and program

      Fundus oculi observation device, ophthalmologic image processing device, and program

      A fundus oculi observation device capable of defining which part in the result of analysis of the layer thickness of a fundus oculi is a part obtained by analyzing a vascular region is provided. A fundus oculi observation device 1 forms a plurality of tomographic images G1-Gm of a fundus oculi Ef. A layer thickness distribution calculator 231 calculates layer thickness distribution of the fundus oculi Ef in a cross section of a tomographic image G based on the tomographic images G1-Gm. A vascular region specifying part 234 specifies a vascular region in the tomographic image G. A controller 210 ...

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    4. Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation

      Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation

      Purpose. To evaluate the inter-visit reproducibility of spectral-domain optical coherence tomography (SD-OCT) measurement of the macular retinal nerve fiber layer thickness (mRNFLT), combined ganglion cell layer and inner plexiform layer (GCL+IPL) thickness, and ganglion cell complex (GCC) thicknesses (sum of mRNFLT and GCL+IPL thicknesses) compared with that of circumpapillary RNFLT (cpRNFLT) and the effect of ocular rotation on reproducibility. Methods. SD-OCT imaging was performed twice on different days in one eye of 58 normal subjects and 73 glaucoma patients. The reproducibility was evaluated for the entire 4.8 mm x 4.8 mm macular area and sub-areas (upper ...

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    5. Spectral-Domain Optical Coherence Tomography of β-zone Peripapillary Atrophy: Influence of Myopia and Glaucoma

      Spectral-Domain Optical Coherence Tomography of β-zone Peripapillary Atrophy: Influence of Myopia and Glaucoma

      Purpose: To investigate the influence of glaucoma and myopia on the cross-sectional configuration of β-zone peripapillary atrophy (PPA-β) using spectral-domain optical coherence tomography (SD-OCT). Methods: Among 100 eyes of 100 consecutive patients with POAG regardless of intraocular pressure level and 100 eyes of 100 normal subjects, cross-sectional B-scan images of PPA-β obtained with SD-OCT were evaluated. PPA bed configurations were classified and associated factors were studied with multivariate analysis. Results: In 147 eyes with PPA-β (84 POAG and 63 normal eyes; P = 0.0012), PPA bed were composed of straight (14 POAG and 27 normal eyes) or downward-curved (19 and ...

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    6. Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography

      Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography
      Purpose: To examine iridotrabecular contact (ITC) as a peripheral anterior synechia (PAS) of patients who underwent penetrating keratoplasty (PKP) using anterior segment Fourier-domain optical coherence tomography (OCT). Methods: Retrospective, observational case series. ITC, ITC index, and ITC area of 60 eyes of 52 patients who underwent PKP at the Department of Ophthalmology in the University of Tokyo Hospital (mean follow-up time 102.8 +/- 116.1 months postoperation) were calculated using the angle analysis mode of a commercially available anterior segment Fourier-domain OCT system (CASIA; TOMEY, Nagoya, Japan). We analyzed the occurrence of ITC, ITC index, and ITC area with preoperative ...
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    7. Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures

      Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures
      Purpose. To identify sex-related differences and age-related changes in individual retinal layer thicknesses in a population of healthy eyes across the lifespan, using spectral domain optical coherence tomography (SD-OCT). Methods. In seven institutes in Japan, mean thicknesses of the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), photoreceptor inner segment (IS), and photoreceptor outer segment (OS) were measured using SD-OCT with a new automated segmentation protocol in 256 healthy subjects. Results. Interoperator coefficients of variability for measurements of each layer ranged from 0 ...
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    8. Identification of Schlemm's Canal and Its Surrounding Tissues by Anterior Segment Fourier Domain Optical Coherence Tomography

      Identification of Schlemm's Canal and Its Surrounding Tissues by Anterior Segment Fourier Domain Optical Coherence Tomography
      Purpose: To identify Schlemm's canal (SC) and trabecular meshwork (TM) by an anterior segment Fourier-domain optical coherence tomography (AS-FD-OCT) with the histological confirmation in enucleated human eyes and to quantitatively evaluate SC and TM in living human eyes. Methods: In enucleated human eyes, the imaging of the anterior chamber angle by AS-FD-OCT was performed before and after surgical expansion of the SC with an injection of a viscoelastic material, followed by histological examination. In sixty living human eyes, the agreement of identification of SC between examiners was evaluated with the Cohen's kappa values, and the lengths of SC ...
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    9. Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes

      Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes
      Objectives  To evaluate the peripapillary distribution of retinal nerve fiber layer thickness (RNFLT) in normal eyes using spectral-domain optical coherence tomography and to study potentially related factors. Methods  In 7 institutes in Japan, RNFLT in 7 concentric peripapillary circles with diameters ranging from 2.2 to 4.0 mm were measured using spectral-domain optical coherence tomography in 251 ophthalmologically normal subjects. Multiple regression analysis for the association of RNFLT with sex, age, axial length, and disc area was performed. Results  Retinal nerve fiber layer thickness decreased linearly from 125 to 89 µm as the measurement diameter increased (P < .001, mixed linear model). Retinal nerve fiber layer thickness correlated with age in all diameters (partial correlation coefficient [PCC] = –0.40 to –0.32; P < .001) and negatively correlated with disc area in the 2 innermost circles but positively correlated in the 3 outermost circles (PCC = –0.30 to –0.22 and 0.17 to 0.20; P ≤ .005). Sex and axial length did not correlate with RNFLT (P > .08). The ...
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    10. Automated layer segmentation of macular OCT images using dual-scale gradient information

      Automated layer segmentation of macular OCT images using dual-scale gradient information
      A novel automated boundary segmentation algorithm is proposed for fast and reliable quantification of nine intra-retinal boundaries in optical coherence tomography (OCT) images. The algorithm employs a two-step segmentation schema based on gradient information in dual scales, utilizing local and complementary global gradient information simultaneously. A shortest path search is applied to optimize the edge selection. The segmentation algorithm was validated with independent manual segmentation and a reproducibility study. It demonstrates high accuracy and reproducibility in segmenting normal 3D OCT volumes. The execution time is about 16 seconds per volume (480x512x128 voxels). The algorithm shows potential for quantifying images from ...
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    11. Evaluation of optic nerve head configurations of superior segmental optic hypoplasia by spectral-domain optical coherence tomography

      Evaluation of optic nerve head configurations of superior segmental optic hypoplasia by spectral-domain optical coherence tomography
      Aims To characterise the optic nerve head (ONH) configurations of superior segmental optic hypoplasia (SSOH) using a spectral-domain optical coherence tomography (SD-OCT). Methods Horizontal cross-sectional images of the ONH were obtained by a SD-OCT in 20 eyes of 14 patients with clinically typical SSOH and 20 age- and refraction-matched normal eyes. Results Extension of retinal pigment epithelium (RPE) over the disc margin was observed in 20 eyes (100%) with SSOH and eight (40%) control eyes (p<0.001). The maximum length of the overhanging RPE measured at the nasal disc margin was significantly longer in eyes with SSOH than in ...
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    12. Cross-sectional Anatomic Configurations of Peripapillary Atrophy Evaluated with Spectral Domain-Optical Coherence Tomography

      Purpose. To evaluate the cross-sectional configurations of peripapillary atrophy (PPA)- and -β in ophthalmologically normal subjects using spectral domain-optical coherence tomography (SD-OCT). Methods. One hundred twenty normal subjects had a complete ophthalmic examination including axial length measurement, standard automated perimetry, fundus imaging with photography, and SD-OCT (3D OCT-1000; Topcon Inc., Tokyo, Japan). PPA- and -β were identified in color photographs of the optic disc. Cross-sectional B-mode images of the peripapillary retina and sclera, including PPA- and -β obtained with SD-OCT, were analyzed. Results. Of 120 normal eyes, 120 (100%) had PPA- and 90 (75%) had PPA-β. In OCT images of ...
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    13. Nerve fiber layer thickness in exudative age-related macular degeneration in Japanese patients

      Purpose To examine the peripapillary retinal nerve fiber (RNFL) thickness in Japanese patients with two major forms of exudative age-related macular degeneration (AMD), i.e., typical AMD and polypoidal choroidal vasculopathy (PCV). Methods This is a prospective observational consecutive study. One hundred patients diagnosed with unilateral exudative AMD, with the fellow eyes free of exudative change, were included. Peripapillary RNFL thickness was measured using three-dimensional Fourier-domain optical coherence tomography (3D-OCT). Peripapillary RNFL thickness was compared between the affected eyes and fellow eyes in 100 patients. Results RNFL thickness in the eyes with exudative AMD did not differ significantly from the ...
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    14. Three-dimensional Profile of Macular Retinal Thickness in Normal Japanese Eyes

      Purpose: To demonstrate the 3-dimensional macular thickness distribution in normal subjects by spectral domain optical coherence tomography (SD-OCT) and evaluate its association with sex, age, and axial length. Methods: Mean regional retinal thickness measurements on the Early Treatment Diabetic Retinopathy Study (ETDRS) layout were obtained by 3-dimensional raster scanning (6 X 6 mm) using SD-OCT in 248 normal eyes of 248 Japanese subjects. Results: Mean foveal thickness was 222 ± 19 µm; it was significantly greater in men (226 ± 19 µm) than in women (218 ± 18 µm; P = 0.002) and did not correlate with age in either sex. Mean sectorial ...
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    1-14 of 14
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    1. (14 articles) Atsuo Tomidokoro
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    Evaluation of optic nerve head configurations of superior segmental optic hypoplasia by spectral-domain optical coherence tomography Automated layer segmentation of macular OCT images using dual-scale gradient information Peripapillary Retinal Nerve Fiber Layer Thickness Determined by Spectral-Domain Optical Coherence Tomography in Ophthalmologically Normal Eyes Identification of Schlemm's Canal and Its Surrounding Tissues by Anterior Segment Fourier Domain Optical Coherence Tomography Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography Spectral-Domain Optical Coherence Tomography of β-zone Peripapillary Atrophy: Influence of Myopia and Glaucoma Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema Ciliary body length revisited by anterior segment optical coherence tomography: implications for safe access to the pars plana for intravitreal injections Evaluation of retinal vascular structure after epiretinal membrane surgery by optical coherence tomography angiography Bivalirudin vs. Heparin on Radial Artery Thrombosis during Transradial Coronary Intervention: An Optical Coherence Tomography Study Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study