1. Articles from julián garcía-feijoo

    1-22 of 22
    1. Utility of optical coherence tomography angiography in detecting vascular retinal damage caused by arterial hypertension

      Utility of optical coherence tomography angiography in detecting vascular retinal damage caused by arterial hypertension

      Objective: To evaluate the potential utility of perfusion density measurements to discriminate patients with arterial hypertension by cardiovascular risk category. Methods: In this cross-sectional study, one eye per subject was evaluated (N = 73). The study cohort was divided into three groups according to the clinical criteria established by the European Guidelines for Arterial Hypertension: 26 controls, 24 patients with low cardiovascular risk, and 23 patients with very high cardiovascular risk. All patients were examined using RS-3000 Advance optical coherence tomography angiography to analyze macular and peripapillary perfusion density. Results: There were no differences among the three risk groups by sex ...

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    2. Anterior Chamber Angle Tissue as an Incidental Optical Coherence Tomography Finding in a Large Healthy Caucasian Child Population

      Anterior Chamber Angle Tissue as an Incidental Optical Coherence Tomography Finding in a Large Healthy Caucasian Child Population

      Purpose: The aim of this study was to describe the presence of anterior chamber angle (ACA) tissue as an incidental optical coherence tomography (OCT) finding in healthy children. Methods: For this cross-sectional study, we reviewed Fourier-domain OCT images obtained in 422 children, who were chosen as candidates for inclusion in a prior study, and who visited our clinic for a routine vision test. The presence of angle tissue was assessed in the nasal and temporal quadrants. On tomographies showing angle tissue , several measurements were made, including ACA width and trabecular meshwork length and size. Results: Hyperreflective tissue was observed in ...

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    3. Analysis of inner and outer retinal layers using spectral domain optical coherence tomography ...

      Analysis of inner and outer retinal layers using spectral domain optical coherence tomography ...

      Objective To analyse the morphological features and diagnostic ability of eight macular retinal layers using a new segmentation software Heidelberg's Spectralis Optical Coherence Tomography (SD-OCT) in healthy, ocular hypertensive and primary open angle glaucoma patients. Methods Single-center, cross-sectional, non-interventional study. 193 eyes from 193 consecutive patients (56 controls, 63 ocular hypertensives, 32 early primary open glaucoma patients and 42 moderate-advanced primary open glaucoma patients). Those patients presenting any retinal disease were excluded. Macular segmentation of the retinal layers was automatically performed using the new segmentation Heidelberg's Spectralis OCT software providing measurements for eight retinal layers. The software provides ...

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    4. Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma

      Diagnostic capacity of SD-OCT segmented ganglion cell complex versus retinal nerve fiber layer analysis for congenital glaucoma

      Purpose To compare the diagnostic performance of circumpapillary retinal nerve fiber layer (cpRNFL) analysis versus segmented ganglion cell complex analysis both by spectral-domain optical coherence tomography (SD-OCT) in children with primary congenital glaucoma (PCG). Methods Participants were 40 children diagnosed with PCG and 60 healthy children. Ophthalmological data collected (for one eye per child) were cup-disc ratio (C/D) and axial length (AL). SD-OCT with automated segmentation was used to measure the thicknesses and volumes of the macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL). For the cpRNFL measurements conventional S-D OCT software ...

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    5. Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis

      Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis

      Objective To examine differences in individual retinal layer thicknesses measured by spectral domain optical coherence tomography (SD-OCT) (Spectralis ® ) produced with age and according to sex. Design Cross-sectional, observational study. Methods The study was conducted in 297 eyes of 297 healthy subjects aged 18 to 87 years. In one randomly selected eye of each participant the volume and mean thicknesses of the different macular layers were measured by SD-OCT using the instrument's macular segmentation software. Main outcome measures Volume and mean thickness of macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer ...

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    6. Impacts of Implantable Collamer Lens V4c Placement on Angle Measurements Made by Optical Coherence Tomography: Two-Year Follow-up

      Impacts of Implantable Collamer Lens V4c Placement on Angle Measurements Made by Optical Coherence Tomography: Two-Year Follow-up

      We appreciate the comments made by Galvis and associates regarding our recently published article in which we report anterior chamber angle narrowing in response to implantable collamer lens (ICL) placement. The mean angle narrowing observed was approximately 39%–41% for the whole population. In response to the first question, in patients with a vault larger than 750 μm, angle reduction was 55.2%–56.7%, compared with 34.7%–38.3% produced in patients with a vault ≤ 750 μm. It is well known that vault is an important determinant of anterior chamber angle, and, as we describe in our article ...

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    7. Anterior Chamber Angle and Trabecular Meshwork Measurements Made by Fourier-domain Optical Coherence Tomography in Healthy White Children

      Anterior Chamber Angle and Trabecular Meshwork Measurements Made by Fourier-domain Optical Coherence Tomography in Healthy White Children

      Purpose: To obtain anterior chamber angle and trabecular meshwork (TM) measurements by Fourier-domain optical coherence tomography (FD-OCT) in a population of healthy white children. Materials and Methods: This was a cross-sectional study examining 409 right eyes of 409 children. Trabecular-iris angle (TIA) and TM length and area were measured by FD-OCT (RTVue 100) in the nasal and temporal quadrants to analyze correlations between angle or TM measurements and age, sex, and refractive error. Results: Mean participant age was 10.5+/-3.4 years (range, 3 to 18 y); 51% were boys. Mean spherical error was 0.56+/-2.4 D ...

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    8. Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population

      Normative database for separate inner retinal layers thickness using spectral domain optical coherence tomography in Caucasian population

      Article Authors Metrics Comments Related Content Abstract Introduction Methods Results Discussion Supporting information Acknowledgments References Reader Comments (0) Media Coverage Figures Abstract Purpose Develop the first normative database of the thickness of every inner retinal layer in the macular area in a healthy, Caucasian population between 18 to 87 years old, using Spectralis Optical Coherence Tomography (OCT). Methods On this transversal, observational study, 300 patients between 18 to 87 years old and without an ophthalmological condition were recruited. Macular OCT scans were performed on all patients (Spectralis OCT, Heidelberg Engineering). An axial length measurement, and keratometry were performed using an ...

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    9. Impacts of implantable collamer lens V4c placement on angle measurements made by optical coherence tomography: two-year follow up

      Impacts of implantable collamer lens V4c placement on angle measurements made by optical coherence tomography: two-year follow up

      Purpose To determine iridocorneal angle changes produced after two years of implantable collamer lens ® (ICL) V4c (STAAR Surgical AG) placement by Fourier-domain optical coherence tomography (FD-OCT). Design Prospective interventional case series. Methods In 54 eyes of 27 myopic subjects FD-OCT (RTVue ® , Optovue Inc.) iridocorneal angle measurements were made before, and 1 month, 3 months, 1 year and 2 years after ICL implant. Trabecular-iris angle (TIA), angle opening distance 500 μm from the scleral spur (AOD 500 ) and iridotrabecular contact length (TICL) were compared among these time points and the quadrants nasal, temporal and inferior. Results Preoperative TIAs were 49.5 ...

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    10. Analysis Of AGE-RELATED Choroidal Layers Thinning In Healthy Eyes Using SWEPT-SOURCE Optical Coherence Tomography

      Analysis Of AGE-RELATED Choroidal Layers Thinning In Healthy Eyes Using SWEPT-SOURCE Optical Coherence Tomography

      Purpose: To study the changes in the choroidal layers thickness with age in a healthy population using swept-source optical coherence tomography. Methods: Retrospective data analysis of a subgroup of eyes from a previous single-center, prospective, cross-sectional, noninterventional study. One hundred and sixty-nine healthy eyes were evaluated using swept-source optical coherence tomography. Inclusion criteria were best-corrected visual acuity between 20/20 and 20/25, spherical equivalent between ±3 diopters, and no systemic or ocular diseases. Two independent investigators determined the macular horizontal choroidal thickness (CT) and the Haller's layer thickness across a 9 mm line centered at the fovea. Subjects ...

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    11. Agreement Between Three Optical Coherence Tomography Devices to Assess the Insertion Distance and Thickness of Horizontal Rectus Muscles

      Agreement Between Three Optical Coherence Tomography Devices to Assess the Insertion Distance and Thickness of Horizontal Rectus Muscles

      PURPOSE: To assess the agreement between two different spectral domain (SD-OCT) and one swept source (SS-OCT) optical coherence tomography device to measure the insertion distance and the thickness of the horizontal rectus muscles. . METHODS: Seventy eyes from 35 healthy patients were studied. Three OCT instruments—Spectralis (Heidelberg Engineering Inc., Heidelberg, Germany), Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA), and Triton (Topcon, Inc., Tokyo, Japan)—were used to measure the limbus insertion distance and the thickness of the lateral rectus and medial rectus muscles. The intraclass correlation coefficient (ICC) was calculated to determine the reproducibility and the agreement between the three ...

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    12. Quantification of trabecular-iris contact and its prevalence by optical coherence tomography in a healthy Caucasian population

      Quantification of trabecular-iris contact and its prevalence by optical coherence tomography in a healthy Caucasian population

      To determine the prevalence of trabecular-iris contact (TIC) and quantify this contact in healthy Caucasian individuals using Fourier-domain optical coherence tomography (FD-OCT). For this cross-sectional study, 2,012 eyes of 1,006 healthy subjects were recruited among individuals undergoing a routine ophthalmologic checkup. In each participant, age, sex, intraocular pressure, and spherical refractive error were first recorded along with anterior chamber depth and volume, central corneal thickness measured with the Pentacam, and axial length with the IOLMaster. Anterior chamber angle variables and the presence of TIC in the horizontal quadrants were determined by anterior segment FD-OCT (RTVue 100®). When TIC ...

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    13. Spectral domain optical coherence tomography to assess the insertion of extraocular rectus muscles

      Spectral domain optical coherence tomography to assess the insertion of extraocular rectus muscles

      Purpose To determine the distance of the horizontal rectus muscle insertion to the limbus using spectral domain optical coherence tomography (SD-OCT) and to evaluate whether results are correlated with sex, age, or axial length. Methods The right eyes of healthy, white subjects were imaged with SD-OCT. Subjects’ sex and age were recorded, and axial length was measured using an optical biometer. The distance from the horizontal rectus insertion to the limbus was measured. The intraclass correlation coefficient (ICC) was used to assess the reproducibility of the measurements with a subset of images. A multivariate model was adjusted to analyze whether ...

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    14. Glaucoma diagnostic capacity of optic nerve head haemoglobin measures compared with spectral domain OCT and HRT III confocal tomography

      Glaucoma diagnostic capacity of optic nerve head haemoglobin measures compared with spectral domain OCT and HRT III confocal tomography

      Purpose The computer program laguna onhe determines optic nerve head haemoglobin (ONH Hb) on retinal photographs based on detecting colour differences. This study compares the diagnostic capacity of Laguna ONhE with that of spectral domain optical coherence tomography (OCT) and confocal tomography (HRT III). Methods In a prospective, observational, cross-sectional study, glaucomatous ( n = 66) and healthy ( n = 52) eyes were examined by Spectralis OCT, HRT III and Laguna ONhE. The following Laguna ONhE variables were determined: ONH Hb across the vertical disc diameter (8&20 Hb), estimated cup–disc ratio (C/D) and the glaucoma discriminant function (GDF), which combines ...

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    15. Fourier domain optical coherence tomography to assess the iridocorneal angle and correlation study in a large Caucasian population

      Fourier domain optical coherence tomography to assess the iridocorneal angle and correlation study in a large Caucasian population

      Background Recently, novel anatomic parameters that can be measured by optical coherence tomography (OCT), have been identified as a more objective and accurate method of defining the iridocorneal angle. The aim of the present study is to measure the iridocorneal angle by Fourier domain (FD) OCT and to identify correlations between angle measurements and subject factors in a large healthy Caucasian population. Methods A cross sectional study was performed in 989 left eyes of 989 healthy subjects. The iridocorneal angle measurements: trabecular-iris angle (TIA), angle opening distance (AOD 500 ) and trabecular-iris space area (TISA 500 ) 500 μm from the scleral ...

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    16. Effects of Implantable Collamer Lens V4c placement on iridocorneal angle measurements by Fourier domain optical coherence tomography

      Effects of Implantable Collamer Lens V4c placement on iridocorneal angle measurements by Fourier domain optical coherence tomography

      Purpose To assess by Fourier domain optical coherence tomography (FD-OCT) changes produced in iridocorneal angle measurements in patients undergoing Visian Implantable Collamer Lens ® (ICL) V4c (STAAR Surgical AG) placement. Design Prospective interventional case series. Methods In 50 eyes of 25 myopic subjects consecutively scheduled for ICL implant, FD-OCT (RTVue ® , Optovue Inc.) iridocorneal angle measurements were made before and 1 and 3 months after surgery. Trabecular-iris angle (TIA), and angle opening distance 500 μm anterior to the scleral spur (AOD 500 ) were compared among the quadrants nasal, temporal and inferior, and correlations with ocular variables including lens vault were examined. Results ...

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    17. Morphometry of the trabecular meshwork in vivo in a healthy population using Fourier domain optical coherence tomography

      Morphometry of the trabecular meshwork in vivo in a healthy population using Fourier domain optical coherence tomography

      Purpose: To measure the length, thickness and area of the trabecular meshwork (TM) in vivo using Fourier domain optical coherence tomography (FD-OCT) in a Caucasian population of healthy subjects. Methods: Cross-sectional study of 1,006 healthy subjects. Left eyes were randomly selected. Age, gender, intraocular pressure and spherical refractive error were noted down. The depth and volume of the anterior chamber and the central corneal thickness were measured with Pentacam®, while IOL Master® was used to measure the axial length. The length, thickness and area of the TM were measured through FD-OCT RTVue®. A study was carried out to determine ...

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    18. Diagnostic ability of macular nerve fiber layer thickness using a new segmentation software in glaucoma suspects

      Diagnostic ability of macular nerve fiber layer thickness using a new segmentation software in glaucoma suspects

      Purpose. To assess the capacity of internal retinal layer thickness measurements made at the macula using new spectral domain OCT software (Spectralis OCT, Heidelberg Engineering) to distinguish between healthy subjects and those with suspected glaucoma. The diagnostic performance of such measurements was also compared with that of conventional peripapillary retinal nerve fiber layer (RNFL) thickness measurements. Methods. The study included 38 subjects with suspected glaucoma and 38 age-matched healthy subjects. In one randomly selected eye of each participant, thickness measurements at the level of the macula were made of the nerve fiber layer (mRNFL), the ganglion cell layer (GCL) and ...

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    19. Artificial Neural Network Techniques to Improve the Ability of Optical Coherence Tomography to Detect Optic Neuritis

      Artificial Neural Network Techniques to Improve the Ability of Optical Coherence Tomography to Detect Optic Neuritis

      Purpose : To analyze the ability of Spectralis optical coherence tomography (OCT) to detect multiple sclerosis (MS) and to distinguish MS eyes with antecedent optic neuritis (ON). To analyze the capability of artificial neural network (ANN) techniques to improve the diagnostic precision. Methods : MS patients and controls were enrolled ( n  = 217). OCT was used to determine the 768 retinal nerve fiber layer thicknesses. Sensitivity and specificity were evaluated to test the ability of OCT to discriminate between MS and healthy eyes, and between MS with and without antecedent ON using ANN. Results : Using ANN technique multilayer perceptrons, OCT could detect MS ...

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    20. Clinical Relevance of Foveal Location on Retinal Nerve Fiber Layer Thickness Using the New FoDi Software in Spectralis Optical Coherence Tomography

      Clinical Relevance of Foveal Location on Retinal Nerve Fiber Layer Thickness Using the New FoDi Software in Spectralis Optical Coherence Tomography

      Purpose:To evaluate the effect of improper foveal location on retinal nerve fiber layer (RNFL) thickness measurements using the new FoDi software in spectral domain optical coherence tomography (Spectralis® SD-OCT, Heidelberg Engineering, Heidelberg, Germany). Methods:Cross-sectional study with 126 subjects: 66 healthy, 30 early and 30 moderate glaucomatous eyes. Fast RNFL scans were performed using the new FoDi technology. The position of the fovea was manually displaced inferiorly after acquisition (producing clockwise torsion of scan circle) and then superiorly (counterclockwise) to generate study sets of images. Differences in RNFL thickness between foveal guided and alternative scans were analyzed and color ...

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    21. Neural networks to identify multiple sclerosis with optical coherence tomography

      Neural networks to identify multiple sclerosis with optical coherence tomography

      Purpose: To compare axonal loss in ganglion cells detected with spectral-domain optical coherence tomography (OCT) in eyes of patients with multiple sclerosis (MS) versus healthy control subjects using an artificial neural network (ANN). To analyse the capability of the ANN technique to improve the detection of retinal nerve fibre layer (RNFL) damage in patients with multiple sclerosis. Methods: Patients with multiple sclerosis (n = 106) and age-matched healthy subjects (n = 115) were enrolled. The Spectralis OCT system was used to obtain the circumpapillary RNFL thickness in both eyes. The 768 RNFL thickness measurements provided by the Spectralis OCT were performed to ...

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    22. Mapping Standard Automated Perimetry to the Peripapillary Retinal Nerve Fiber Layer in Glaucoma

      purpose. To establish a map relating visual field (VF) test points to corresponding areas of the retinal nerve fiber layer (RNFL) measured with optical coherence tomography (OCT) in patients with glaucomatous optic neuropathy.methods. One hundred four consecutive subjects with open-angle glaucoma were prospectively selected. All subjects underwent standard automated perimetry (SAP) and imaging with OCT. Factor analyses of the mean thresholds for the SAP test points were performed, independently for each hemifield, to define regions of related points. Pearson correlations were then calculated between the VF regions and peripapillary RNFL thickness measured with OCT at each of the 12 ...

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    1-22 of 22
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    Neural networks to identify multiple sclerosis with optical coherence tomography Clinical Relevance of Foveal Location on Retinal Nerve Fiber Layer Thickness Using the New FoDi Software in Spectralis Optical Coherence Tomography Artificial Neural Network Techniques to Improve the Ability of Optical Coherence Tomography to Detect Optic Neuritis Diagnostic ability of macular nerve fiber layer thickness using a new segmentation software in glaucoma suspects Morphometry of the trabecular meshwork in vivo in a healthy population using Fourier domain optical coherence tomography Effects of Implantable Collamer Lens V4c placement on iridocorneal angle measurements by Fourier domain optical coherence tomography Spectral domain optical coherence tomography to assess the insertion of extraocular rectus muscles Quantification of trabecular-iris contact and its prevalence by optical coherence tomography in a healthy Caucasian population Agreement Between Three Optical Coherence Tomography Devices to Assess the Insertion Distance and Thickness of Horizontal Rectus Muscles Intravitreal Ranibizumab Monotherapy or Combined with Laser for Diabetic Macular Edema (OCT guided study) Prospective evaluation of drug eluting self‐apposing stent for the treatment of unprotected left main coronary artery disease: 1‐year results of the TRUNC study Clinical validation of the RTVue optical coherence tomography angiography image quality indicators