1. Articles from p. villoslada

    1-5 of 5
    1. Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

      Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography

      Neuromyelitis optica (NMO) is an inflammatory autoimmune disease of the central nervous system that preferentially targets the optic nerves and spinal cord. The clinical presentation may suggest multiple sclerosis (MS), but a highly specific serum autoantibody against the astrocytic water channel aquaporin-4 present in up to 80% of NMO patients enables distinction from MS. Optic neuritis may occur in either condition resulting in neuro-anatomical retinal changes. Optical coherence tomography (OCT) has become a useful tool for analyzing retinal damage both in MS and NMO. Numerous studies showed that optic neuritis in NMO typically results in more severe retinal nerve fiber ...

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    2. Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

      Background: Retinal optical coherence tomography (OCT) permits quantification of retinal layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS). Measurement artefacts may limit the use of OCT to MS research. Objective: An expert task force convened with the aim to provide guidance on the use of validated quality control (QC) criteria for the use of OCT in MS research and clinical trials. Methods: A prospective multi-centre ( n = 13) study. Peripapillary ring scan QC rating of an OCT training set ( n = 50) was followed by a test set ( n = 50). Inter-rater agreement was calculated using kappa statistics. Results were ...

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    3. Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis

      BackgroundStudying axonal loss in the retina is a promising biomarker for multiple sclerosis (MS). Our aim was to compare optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT) techniques to measure the thickness of the retinal nerve fiber layer (RNFL) in patients with MS, and to explore the relationship between changes in the RNFL thickness with physical and cognitive disability. We studied 52 patients with MS and 18 proportionally matched controls by performing neurological examination, neuropsychological evaluation using the Brief Repetitive Battery-Neuropsychology and RNFL thickness measurement using OCT and HRT.ResultsWe found that both OCT and HRT could define a ...
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    4. Retinal nerve fiber layer atrophy is associated with physical and cognitive disability in multiple sclerosis.

      Background Studying axonal loss in the retina is a promising biomarker for multiple sclerosis (MS). Our aim was to compare optical coherence tomography (OCT) and Heidelberg retinal tomography (HRT) techniques to measure the thickness of the retinal nerve fiber layer (RNFL) in patients with MS, and to explore the relationship between changes in the RNFL thickness with physical and cognitive disability. We studied 52 patients with MS and 18 proportionally matched controls by performing neurological examination, neuropsychological evaluation using the Brief Repetitive Battery-Neuropsychology and RNFL thickness measurement using OCT and HRT. Results We found that both OCT and HRT could ...
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    1-5 of 5
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  2. Topics in the News

    1. (2 articles) UCSF
    2. (2 articles) Johns Hopkins University
    3. (2 articles) UT Southwestern Medical Center
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    6. (2 articles) Zhejiang University
    7. (2 articles) Raju Poddar
    8. (1 articles) Heinrich-Heine University Düsseldorf
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    Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria Neuromyelitis optica and multiple sclerosis: Seeing differences through optical coherence tomography Usefulness of optical coherence tomography to distinguish optic neuritis associated with AQP4 or MOG in neuromyelitis optica spectrum disorders High performance OCTA enabled by combining features of shape, intensity, and complex decorrelation A Novel 3D Segmentation Approach for Extracting Retinal Layers from Optical Coherence Tomography Images Assessing the Outcomes of Focused Heating of the Skin by a Long-Pulsed 1064 nm Laser with an Integrated Scanner, Infrared Thermal Guidance, and Optical Coherence Tomography Albumin‐PEG‐Based Biomaterial for Laser‐Tissue Soldering and Its Real‐Time Monitoring With Swept‐Source Optical Coherence Tomography Asymmetric response to ranibizumab in mixed choroidal neovascularization in a neovascular age-related macular degeneration diagnosed on OCT angiography OCT-angiography detects longitudinal microvascular changes in glaucoma: a systematic review Investigation of Gd2O3: Er3+/Yb3+ Upconversion Nanoparticles (UCNPs) as a Multi‐model Contrast Agent for Functional Optical Coherence Tomography Optical Coherence Tomography Angiography in patients with Neurofibromatosis type 1: a quantitative vascular prospective study In Vivo Quantitative Analysis of Anterior Chamber White Blood Cell Mixture Composition Using Spectroscopic Optical Coherence Tomography