1. Articles from qiuhong zhu

    1-4 of 4
    1. Assessment of the effects of ultrasound-mediated alcohols on skin optical clearing

      Our previous studies have shown the ultrasound-induced skin optical clearing enhancement with topical application of glycerol on in vitro porcine skin and in vivo human skin. The objective of this study was to find more effective ultrasound-alcohol combinations on skin optical clearing. The effect of sonophoretic delivery (SP) in combination with a series of alcohols such as glycerol, propylene glycol, butanediol, butanol, polyethylene glycol (PEG200, PEG400) on skin optical clearing was investigated. Light transmittance and imaging depth of in vitro porcine skin were measured with spectroscopy and optical coherence tomography (OCT). Sixty percent alcohols and ultrasound (SP) with a frequency ...
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    2. Combined Effect of Ultrasound-SLS on Skin Optical Clearing

      Our previous studies demonstrated the ultrasound-induced skin optical clearing enhancement with topical application of optical clearing agents on in vitro porcine skin and in vivo human skin. The objective of this study was to develop more effective methods by simultaneously using two kinds of skin permeation enhancers. The effect of ultrasound (SP) in combination with a chemical enhancer, sodium lauryl sulfate (SLS), on skin optical clearing was investigated. Light transmittance and imaging depth of in vitro porcine skin were measured with spectroscopy and optical coherence tomography (OCT). Three treatments were performed: 1) 60% glycerol (60% Gly); 2) 60% glycerol $+ $15-min ...
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    3. Skin optical clearing enhancement with penetration enhancer azone using spectroscopy and optical coherence tomography

      In order to find a non-invasive way to improve the efficacy of skin optical clearing with topically applied optical clearing agents (OCA), we evaluated the effect of azone ® (epsilon-Laurocapram) as a chemical penetration enhancer on optical clearing of intact skin in vitro. Fresh porcine skin ... [Proc. SPIE 6791, 67910F (2008)] published Mon Jun 9, 2008.
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    4. Sonophoretic Delivery for Contrast and Depth Improvement in Skin Optical Coherence Tomography

      Our previous studies demonstrated the feasibility of using a sonophoretic delivery method to enhance skin light transmittance with topical application of optical clearing agents using spectroscopy. In this study, we examined the effect of ultrasound [surgeon-performed (SP)] on optical coherence tomography (OCT) imaging depth and contrast of in vitro and in vivo skin. Sixty percent glycerol (G) and SP with a frequency of 1 MHz and a power of 0.75 W over a 3 cm probe was simultaneously applied for 15 min. We find that 60% G/SP results in a twofold increase in achievable OCT imaging depth for ...
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    1-4 of 4
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