1. Articles from elise héon

    1-7 of 7
    1. Optical Coherence Tomography–Guided Decisions in Retinoblastoma Management

      Optical Coherence Tomography–Guided Decisions in Retinoblastoma Management

      Purpose Assess the role of handheld optical coherence tomography (OCT) in guiding management decisions during diagnosis, treatment, and follow-up of eyes affected by retinoblastoma. Design Retrospective, noncomparative, single-institution case series. Participants All children newly diagnosed with retinoblastoma from January 2011 to December 2015 who had an OCT session during their active treatment at The Hospital for Sick Children (SickKids) in Toronto, Canada. The OCT sessions for fellow eyes of unilateral retinoblastoma without any suspicious lesion and those performed more than 6 months after the last treatment were excluded. Methods Data collected included age at presentation, sex, family history, RB1 mutation ...

      Read Full Article
    2. Visual Function and Central Retinal Structure in Choroideremia

      Visual Function and Central Retinal Structure in Choroideremia

      Purpose : To define the clinical phenotype of a cohort of patients affected with choroideremia. Methods : A retrospective study of patients with choroideremia included two centers. Data collected included age, visual acuity, refractive error, color vision, kinetic perimetry, optical coherence tomography (OCT), and genotype information. Results : Sixty male participants were recruited. Genotype information was available for 58 cases, and nonsense mutations were most commonly observed. Eight novel mutations were identified including a missense mutation. The mean age at the first visit was 30.1 years (range, 5–65 years) and thirty-seven patients (61%) had more than one visit with a mean ...

      Read Full Article
    3. Hand-held high-resolution spectral domain optical coherence tomography in retinoblastoma: clinical and morphologic considerations

      Hand-held high-resolution spectral domain optical coherence tomography in retinoblastoma: clinical and morphologic considerations

      Purpose Hand-held spectral domain optical coherence tomography (HHSD OCT) has greatly expanded the imaging/diagnostic capacity for clinicians managing children with intraocular retinoblastoma. We present our early experience with HHSD OCT and conventional spectral domain OCT imaging in these patients. Methods In this retrospective cross-sectional observational study, infants were imaged during examination under anaesthesia with HHSD OCT in the supine position. Older cooperative retinoblastoma patients were additionally imaged with upright conventional OCT. Clinical data were derived from patient charts and from a prospectively maintained interinstitutional retinoblastoma database. Complementary imaging techniques, including RetCam™, fluorescein angiography and B-scan ultrasound, were assessed. Results ...

      Read Full Article
    4. Detection of optic nerve disease in retinoblastoma by use of spectral domain optical coherence tomography

      Detection of optic nerve disease in retinoblastoma by use of spectral domain optical coherence tomography

      We present the case of a child affected with retinoblastoma and evolving optic nerve pathology detected by spectral domain optical coherence tomography (SD-OCT) before magnetic resonance imaging. At 6 months of age, the patient was diagnosed with bilateral retinoblastoma, which was managed with systemic chemotherapy and focal therapy. Six months after the third and final cycle of systemic chemotherapy, the right optic disk clinically appeared progressively edematous, raising concerns of tumor infiltration of the optic nerve head. Images obtained via magnetic resonance imaging could not confirm the presence of a tumor at the optic nerve head, whereas findings on SD-OCT ...

      Read Full Article
    5. High-resolution retinal imaging in young children using a handheld scanner and Fourier-domain optical coherence tomography

      Purpose To test the feasibility and applicability of a handheld probe for Fourier-domain optical coherence tomography (Fd-OCT) retinal imaging in infants and children. Methods Thirty children ages 7 months to 9.9 years, with (10 of 30) or without (20 of 30) retinal pathology, were imaged with Fd-OCT. Imaging was performed under sedation in 10 of 30 children ages 7 months to 3.7 years. A high-resolution Fd-OCT system (axial resolution: 4.5 μm; acquisition speeds: 1000 A-scans/frame, 9 frames/second), constructed at the UC Davis Medical Center, in conjunction with a handheld scanner, was used for retinal imaging ...
      Read Full Article
    6. Detailed analysis of retinal function and morphology in a patient with autosomal recessive bestrophinopathy (arb)

      Abstract  The objective of the paper is to study the retinal microstructure and function in a patient with autosomal recessive bestrophinopathy (ARB). Retinal function and morphology assessment in a patient diagnosed with a biallelic mutation in the BEST1 gene (heterozygote mutations: Leu88del17 and A195V) included: full-field electroretinogram (ffERG) and multifocal electroretinogram (mfERG), electro-oculogram (EOG) testing, and imaging with a high-resolution Fourier-domain optical coherence tomography (Fd-OCT) system (UC Davis Medical Center; axial resolution: 4.5 μm, acquisition speed: 9 frames/s, 1,000 A-scans/frame) combined with a flexible scanning head (Bioptigen Inc.). The 11-year old asymptomatic boy showed a well-demarcated ...
      Read Full Article
    7. Retinal Morphological Changes of Patients With X-linked Retinoschisis Evaluated by Fourier-Domain Optical Coherence Tomography

      Retinal Morphological Changes of Patients With X-linked Retinoschisis Evaluated by Fourier-Domain Optical Coherence Tomography
      Objective  To investigate the retinal microstructure and lamination of patients affected with X-linked retinoschisis (XLRS) using high-resolution imaging modalities. Methods  Patients diagnosed as having XLRS underwent assessment. Visual function testing included visual acuity, color vision, and full-field electroretinography. We used a high-resolution Fourier-domain optical coherence tomography (FD-OCT) system (4.5-µm axial resolution; 9 frames/s; 1000 A-scans per frame) combined with a handheld scanner. Macular image evaluation included schisis localization and retinal layer integrity. Results  Six patients with XLRS and identified mutations in the XLRS1 gene underwent testing. Visual acuity ranged from 0.2 to 1.6 logMAR (logarithm of ...
      Read Full Article
      Mentions: UC Davis
    1-7 of 7
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (4 articles) University of Toronto
    2. (3 articles) UC Davis
    3. (1 articles) Universität Rostock
    4. (1 articles) Ontario Cancer Institute
    5. (1 articles) Brigham and Women’s Hospital
    6. (1 articles) Leica
    7. (1 articles) National Institutes of Health
    8. (1 articles) Tokyo Medical & Dental University
    9. (1 articles) Carl Zeiss Meditec
  3. Popular Articles

  4. Picture Gallery

    Retinal Morphological Changes of Patients With X-linked Retinoschisis Evaluated by Fourier-Domain Optical Coherence Tomography Detection of optic nerve disease in retinoblastoma by use of spectral domain optical coherence tomography Hand-held high-resolution spectral domain optical coherence tomography in retinoblastoma: clinical and morphologic considerations Visual Function and Central Retinal Structure in Choroideremia Optical Coherence Tomography–Guided Decisions in Retinoblastoma Management The Structural and Comparative Analysis of Intravitreal Dexamethasone Implant (Ozurdex) and Anti-VEGF Injection in Branched Retinal Vein Occlusion Patients by Optical Coherence Tomography Angiography Images Quantitation Vascular Responses to First-Generation Sirolimus-Eluting Stents and Bare-Metal Stents Beyond 10 Years Ocular Parameters Evaluation in Relation to the Refractive Error using Optical Coherence Topography Micro Optical Coherence Tomography for Coronary Imaging Macular Vessel Density in Diabetic Retinopathy Patients: How Can We Accurately Measure and What Can It Tell Us? Systems and methods for long working distance optical coherence tomography (OCT) Evaluation of the retinal nerve fiber layer with optic coherence tomography in patients with alcohol use disorder