All Articles from Mitra Sehi -Optical Coherence Tomography News

Articles from Mitra Sehi

1-8 of 8
1. Longitudinal and Cross-Sectional Analyses of Age and Intraocular Pressure Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness
  
  Explore IOVS Journal Mar 12 2016 Ophthalmology
  
  Purpose : To study the effect of age and intraocular pressure (IOP) on retinal nerve fiber layer (NFL) and ganglion cell complex (GCC) thickness in normal eyes. Methods : We analyzed the data from subjects enrolled in the multi-center longitudinal Advanced Imaging for Glaucoma (AIG) Study (www.AIGStudy.net). The data included yearly visits from the normal subjects group in the AIGS study. Fourier-domain optical coherence tomography (OCT) was used to map the thickness of NFL and GCC three times on each visit. To adjust for the repeated measurements for the same subjects, mixed effect models were used to evaluate the longitudinal ...
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  Mentions: University of Pittsburgh Oregon Health & Science University University of Southern California
2. Predicting Development of Glaucomatous Visual Field Conversion Using Baseline Fourier-Domain Optical Coherence Tomography
  
  Explore American Journal of Ophthalmology Dec 1 2015 Ophthalmology
  
  Purpose To predict the development of glaucomatous visual field (VF) defects using Fourier-domain optical coherence tomography (FD-OCT) measurements at baseline visit. Design Multi-center longitudinal observational study. Glaucoma suspects and pre-perimetric glaucoma participants in the Advanced Imaging for Glaucoma Study. Methods The optic disc, the peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) were imaged with FD-OCT VF was assessed every 6 months. Conversion to perimetric glaucoma was defined by VF pattern standard deviation (PSD) or glaucoma hemifield test (GHT) outside normal limits on 3 consecutive tests. Hazard ratios were calculated with the Cox proportional hazard model ...
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  Mentions: University of Pittsburgh Oregon Health & Science University Srinivas R. Sadda
3. Glaucoma Diagnosis and Monitoring Using Advanced Imaging Technologies
  
  Explore touchophthalmology.com Aug 18 2013 Ophthalmology
  
  Advanced ocular imaging technologies facilitate objective and reproducible quantification of change in glaucoma but at the same time, impose new challenges on scientists and clinicians for separating true structural change from imaging noise. This review examines time-domain and spectral-domain optical coherence tomography, confocal scanning laser ophthalmoscopy and scanning laser polarimetry technologies and discusses the diagnostic accuracy and the ability of each technique for evaluation of glaucomatous progression. A broad review of the current literature reveals that objective assessment of retinal nerve fiber layer, ganglion cell complex and optic nerve head topography may improve glaucoma monitoring when used as a complementary ...
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  Mentions: University of Miami
4. Retinal oximetry using ultrahigh-resolution optical coherence tomography
  
  Explore Medical Journals Publisher Dec 12 2012 Ophthalmology
  
  Background: The purpose of this study was to investigate the repeatability of retinal oximetry using slit-lamp adapted ultrahigh-resolution optical coherence tomography (SL-UHR-OCT). Methods: SL-UHR-OCT was developed and fringe patterns were obtained for a major retinal artery and a major retinal vein. A-scans at the central wavelengths of 805 nm and 855 nm were analyzed for calculating optical density ratios (ODRs), from which the percentage oxygen saturation was calculated. Measurements were made on two occasions for each person. Repeatability and coefficients of repeatability were calculated. Results: The mean ODRs of the artery were 0.79 ± 0.86 and 0.88 ± 0 ...
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  Mentions: Superlum Wenzhou Medical College University of Miami
5. Relationship among visual field, blood flow, and neural structure measurements in glaucoma
  
  Explore iovs.org Mar 30 2012 Ophthalmology
  
  Purpose:To determine the relationship among visual field, neural structural, and blood flow measurements in glaucoma. Methods:Case-control study. Forty-seven eyes of 42 patients with perimetric glaucoma were age-matched with 27 normal eyes of 27 patients. All patients underwent Doppler Fourier-domain optical coherence tomography to measure retinal blood flow and standard glaucoma evaluation with visual field testing and quantitative structural imaging. Linear regression analysis was performed to analyze the relationship among visual field, blood flow, and structure, after all variables were converted to logarithmic decibel scale. Results:Retinal blood flow was reduced in glaucoma eyes compared to normal eyes (p
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  Mentions: Oregon Health & Science University University of Southern California University of Miami
6. Detection of Progressive Retinal Nerve Fiber Layer Thickness Loss With Optical Coherence Tomography Using 4 Criteria for Functional Progression
  
  Explore LWW Online Jun 8 2011 Ophthalmology
  
  Purpose: To compare the rates of retinal nerve fiber layer (RNFL) thickness loss using optical coherence tomography (OCT) in progressing versus nonprogressing eyes using 4 methods to define functional progression. Methods: Normal and glaucomatous eyes with >=3 years of follow up were prospectively enrolled. Standard automated perimetry (Swedish Interactive Threshold Algorithm Standard 24-2) and OCT (Stratus OCT, Carl Zeiss Meditec, Dublin, CA) imaging were performed every 6 months in glaucomatous eyes. OCT imaging was performed annually in normal eyes. Functional progression was determined using early manifest glaucoma trial criterion, visual field index (VFI), Progressor software, and the 3-omitting method. Results ...
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  Mentions: Carl Zeiss Meditec
7. Quantification of Change in Axonal Birefringence Following Surgical Reduction in Intraocular Pressure
  
  Explore Ophthalmic Surgery, Lasers and Imaging Jan 14 2011 Ophthalmology
  
  BACKGROUND AND OBJECTIVE The purpose of this study was to examine the hypothesis that retinal nerve fiber layer (RNFL) birefringence increases following surgical reduction of intraocular pressure (IOP). PATIENTS AND METHODS Twenty-six glaucomatous eyes requiring trabeculectomy or drainage implant were enrolled. Optical coherence tomography (OCT), scanning laser polarimetry (SLP), and IOP measurements were performed preoperatively and 3 months postoperatively. The OCT and SLP images were aligned using a new algorithm that aligns the vessels in an OCT image to those in the corresponding SLP reflectance image. The SLP retardance values at the location of the OCT scan circle were then ...
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  Mentions: University of Miami
8. Diagnostic Ability of Fourier-Domain vs Time-Domain Optical Coherence Tomography for Glaucoma Detection
  
  Explore American Journal of Ophthalmology Jul 8 2009 Ophthalmology
  
  Purpose To compare retinal nerve fiber layer (RNFL) thickness assessments and the discriminating ability of Fourier-domain optical coherence tomography (FD-OCT) with that of time-domain optical coherence tomography (TD-OCT) for glaucoma detection. Design Prospective, nonrandomized, observational cohort study. Methods Normal and glaucomatous eyes underwent complete examination, standard automated perimetry, optic disc photography, TD-OCT (Stratus OCT; Carl Zeiss Meditec, Dublin, California, USA), and FD-OCT (RTVue; Optovue Inc, Fremont, California, USA). One eye per subject was enrolled. Two consecutive scans were acquired using a 3.46-mm diameter scan with TD-OCT and a 3.45-mm diameter scan with FD-OCT. For each of 5 RNFL ...
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  Mentions: Optovue Carl Zeiss Meditec University of Miami
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