1. Articles from Valentin Gelikonov

    1-5 of 5
    1. Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use

      Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use

      This work is dedicated to the development of the OCT system with angiography for everyday clinical use. Two major problems were solved during the development: compensation of specific natural tissue displacements, induced by contact scanning mode and physiological motion of patients (eg, respiratory and cardiac motions) and online visualization of vessel cross‐sections to provide feedback for the system operator.

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    2. Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography

      Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography

      A novel machine-learning method to distinguish between tumor and normal tissue in optical coherence tomography (OCT) has been developed. Pre-clinical murine ear model implanted with mouse colon carcinoma CT-26 was used. Structural-image-based feature sets were defined for each pixel and machine learning classifiers were trained using “ground truth” OCT images manually segmented by comparison with histology. The accuracy of the OCT tumour segmentation method was then quantified by comparing with fluorescence imaging of tumors expressing genetically encoded fluorescent protein KillerRed that clearly delineates tumor borders. Since the resultant 3D tumor/normal structural maps are inherently co-registered with OCT derived maps ...

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    3. Dual instrument for in vivo and ex vivo OCT imaging in an ENT department

      Dual instrument for in vivo and ex vivo OCT imaging in an ENT department

      A dual instrument is assembled to investigate the usefulness of optical coherence tomography (OCT) imaging in an ear, nose and throat (ENT) department. Instrument 1 is dedicated to in vivo laryngeal investigation, based on an endoscope probe head assembled by compounding a miniature transversal flying spot scanning probe with a commercial fiber bundle endoscope. This dual probe head is used to implement a dual channel nasolaryngeal endoscopy-OCT system. The two probe heads are used to provide simultaneously OCT cross section images and en face fiber bundle endoscopic images. Instrument 2 is dedicated to either in vivo imaging of accessible surface ...

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    4. Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study

      Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study
      The capabilities of cross-polarization optical coherence tomography (CP OCT) for early bladder-cancer detection are assessed in statistical study and compared with the traditional OCT. Unlike the traditional OCT that demonstrates images only in copolarization, CP OCT acquires images in cross-polarization and copolarization simultaneously. 116 patients with localized flat suspicious lesions in the bladder were enrolled, 360 CP OCT images were obtained and analyzed. CP OCT demonstrated sensitivity 93.7% (vs. 81.2%, <0.0001), specificity 84% (vs. 70.0%, <0.001) and accuracy 85.3% (vs. 71.5%, <0.001) in detecting flat malignant bladder lesions, which is significantly better ...
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    5. Monitoring oncological surgery using optical coherence tomography

      Monitoring oncological surgery using optical coherence tomography
      Detailed, real-time imaging allows for adjustment of surgical margins, thus sparing healthy tissue and increasing the likelihood of complete tumor removal. Development of local recurrence is one of the main causes of unsatisfactory long-term recovery prospects following cancer surgery. Determining the adequate balance between radical tumor removal and maximum preservation of the surrounding tissue is therefore very important for cancer management and, subsequently, the patient's quality of life. Rates of recurrence following surgical resection are appreciably high for a number of cancers. Following transurethral resection of bladder tumors (TURBT), they are reported to be as high as 40–80 ...
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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) Nizhny Novgorod State Medical Academy
    2. (5 articles) Grigory V. Gelikonov
    3. (5 articles) Valentin M. Gelikonov
    4. (4 articles) Institute of Applied Physics
    5. (4 articles) Elena V. Zagaynova
    6. (4 articles) Natalia D. Gladkova
    7. (3 articles) Elena B. Kiseleva
    8. (2 articles) University of Toronto
    9. (2 articles) Olga S. Streltsova
    10. (2 articles) I. Alex Vitkin
    11. (1 articles) Joost Daemen
    12. (1 articles) Notal Vision
    13. (1 articles) Thorlabs
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    Monitoring oncological surgery using optical coherence tomography Cross-polarization optical coherence tomography for early bladder-cancer detection: statistical study Dual instrument for in vivo and ex vivo OCT imaging in an ENT department Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use Fantom Encore Sirolimus-eluting Bioresorbable Scaffold for Treatment of De-novo CAD: the ENCORE-I Study Assessment of Microcirculatory Dysfunction in Septic Shock Patients by OCTA OCT system used at home demonstrates potential for daily monitoring of AMD Optical Coherence Tomography Biomarkers of the Outer Blood—Retina Barrier in Patients with Diabetic Macular Oedema Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated Multi-channel swept source optical coherence tomography concept based on photonic integrated circuits Assessment of Retinal Vessel Density in Adult-Onset Foveomacular Vitelliform Dystrophy by Optical Coherence Tomography Angiography