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Repair of Descemet Membrane Detachments With the Assistance of Anterior Segment Optical Coherence Tomography
Explore Article Archives of Ophthalmology (May 11 2008)
Extensive Descemet membrane detachment (DMD) is a rare complication of intraocular surgery that can lead to corneal decompensation.1 Although DMD may resolve spontaneously, surgical repair frequently is required. The diagnosis may be difficult because corneal edema can obscure visualization of the Descemet membrane (DM). Ultrasonographic biomicroscopy (UBM) has been the standard for imaging DMD in patients with corneal opacity.2 Anterior segment optical coherence tomography (OCT) is a new technique for imaging anterior segment anatomy to evaluate narrow angles, flaps created with laser-assisted in situ keratomileusis, and corneas after DM-stripping automated endothelial keratoplasty.3 We report 2 cases of extensive DMD in ... (Read Full Article)
Comment on Article Mentions: Shan C. Lin Michael R. Hee Carl Zeiss Meditec
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Optical coherence tomography of the eye (Thesis)
Explore Article DSpace@MIT (Feb 1 1997)
Optical Coherence Tomography (OCT) is a new technique for high-resolution, cross-sectional imaging of tissue in which the time-of-flight delay of light reflected from internal tissue structures is resolved with high precision using interferometer. Tomographic images are obtain which are analogous to those provided by ultrasound except that image contrast relies on differences in optical rather than acoustic properties of tissue. The use of light rather than sound enable higher resolution (10 um) and non-contact imaging. A clinically viable high-sensitivity, fiber-optic based OCT instrument has been constructed based on engineering principles derived from optical communication theory. Computer algorithms have also been ...
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Comment on Article Mentions: Massachusetts Institute of Technology James G. Fujimoto Michael R. Hee
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In vivo retinal imaging by optical coherence tomography
Explore Article opticsinfobase.org (Aug 14 1993)
We describe what are to our knowledge the first in vivo measurements of human retinal structure with optical coherence tomography. These images represent the highest depth resolution in vivo retinal images to date. The tomographic system, image-processing techniques, and examples of high-resolution tomographs and their clinical relevance are discussed
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Comment on Article Mentions: Carmen A. Puliafito Joseph A. Izatt Massachusetts Institute of Technology
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Optical Coherence Tomography
Explore Article Science/AAAS (Nov 15 1991)
A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively (Read Full Article)
Comment on Article Mentions: Carmen A. Puliafito Massachusetts Institute of Technology James G. Fujimoto





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Great video Jim!
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Dear Prof. Dr. Gary S. Mintz, You are an extraordinary expert in imaging, an intelligence ...
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