1. Articles from Thanh-Tin P. Nguyen

    1-4 of 4
    1. Peripheral OCT Assisted by Scleral Depression in Retinopathy of Prematurity

      Peripheral OCT Assisted by Scleral Depression in Retinopathy of Prematurity

      Objective: To determine whether handheld widefield optical coherence tomography (OCT) can be used to document retinopathy of prematurity (ROP) stage while using scleral depression to improve peripheral views. Design: Prospective observational study. Participants: Consecutive neonates admitted to the neonatal intensive care unit (NICU) in a single academic medical center who also met criteria for ROP screening and consented for research imaging. Methods: Scleral depression was combined with widefield OCT using an investigational 400-kHz, 55-degree field of view handheld OCT during routine ROP screening from October 28, 2020 to March 03, 2021. Main outcome measures: Acquisition of en face and B-scan ...

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    2. Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity

      Advantages of Widefield Optical Coherence Tomography in the Diagnosis of Retinopathy of Prematurity

      Recent advances in portable optical coherence tomography (OCT) and OCT angiography (OCTA) have resulted in wider fields of view (FOV) and shorter capture times, further expanding the potential clinical role of OCT technology in the diagnosis and management of retinopathy of prematurity (ROP). Using a prototype, handheld OCT device, retinal imaging was obtained in non-sedated infants in the neonatal intensive care unit (NICU) as well as sedated infants in the operating room of Oregon Health & Science University (OHSU) Hospital. In this observational study, we provide an overview of potential advantages of OCT-based disease assessment in ROP. We observed that next-generation ...

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    3. Volumetric directional optical coherence tomography

      Volumetric directional optical coherence tomography

      Photoreceptor loss and resultant thinning of the outer nuclear layer (ONL) is an important pathological feature of retinal degenerations and may serve as a useful imaging biomarker for age-related macular degeneration. However, the demarcation between the ONL and the adjacent Henle’s fiber layer (HFL) is difficult to visualize with standard optical coherence tomography (OCT). A dedicated OCT system that can precisely control and continuously and synchronously update the imaging beam entry points during scanning has not been realized yet. In this paper, we introduce a novel imaging technology, Volumetric Directional OCT (VD-OCT), which can dynamically adjust the incident beam ...

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    4. 105° field of view non-contact handheld swept-source optical coherence tomography

      105° field of view non-contact handheld swept-source optical coherence tomography

      We demonstrate a handheld swept-source optical coherence tomography (OCT) system with a 400 kHz vertical-cavity surface-emitting laser (VCSEL) light source, a non-contact approach, and an unprecedented single shot 105° field of view (FOV). We also implemented a spiral scanning pattern allowing real-time visualization with improved scanning efficiency. To the best of our knowledge, this is the widest FOV achieved in a portable non-contact OCT retinal imaging system to date. Improvements to the FOV may aid the evaluation of retinal diseases such as retinopathy of prematurity, where important vitreoretinal changes often occur in the peripheral retina.

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) Oregon Health & Science University
    2. (3 articles) Center for Ophthalmic Optics and Lasers
    3. (2 articles) Simon Fraser University
    4. (1 articles) National Institutes of Health
    5. (1 articles) Thorlabs
    6. (1 articles) FLIR
    7. (1 articles) Superlum
    8. (1 articles) e2v
    9. (1 articles) Gould Fiber Optics
    10. (1 articles) Columbia University
    11. (1 articles) University of Rochester
    12. (1 articles) Stanford University
    13. (1 articles) Johns Hopkins University
    14. (1 articles) National University of Singapore
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