1. Articles from Philippe Valmaggia

    1-5 of 5
    1. Imaging the Vitreous with a Novel Boosted Optical Coherence Tomography Technique: Posterior Vitreous Detachment

      Imaging the Vitreous with a Novel Boosted Optical Coherence Tomography Technique: Posterior Vitreous Detachment

      Purpose: To evaluate the anatomic changes in the vitreous associated with evolving posterior vitreous detachment (PVD) over the macula. Methods: A novel scanning method by which 4 A-scans at each position were averaged prior to the Fourier transform that boosted the image quality sufficiently such that frame averaging could occur. B-scans and volume rendered images of eyes with evidence of any partial separation of the vitreous in the macular regions were evaluated. Results: There were 43 eyes of 23 subjects with particular attention paid to the findings of 7 eyes with various stages of PVD occurring over the macula. In ...

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    2. Imaging the Vitreous with a Novel Boosted Optical Coherence Tomography Technique: Vitreous Degeneration and Cisterns

      Imaging the Vitreous with a Novel Boosted Optical Coherence Tomography Technique: Vitreous Degeneration and Cisterns

      Purpose: To evaluate the degenerative findings including cistern formation in the premacular vitreous using optical coherence tomography (OCT). Methods: A novel enhanced vitreous imaging method by which 4 A-scans at each position were averaged prior to the Fourier transform increased the image quality per frame so that subsequent image registration for averaging could occur. Analysis of B-scans and volume rendered images of eyes in subjects of various ages was performed. Results: There were 43 eyes of 23 subjects ranging in age from 23 - 68 years. The texture in the vitreous images suggests specific orientations of the vitreous fibers in the ...

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    3. Reference database of total retinal vessel surface area derived from volume-rendered optical coherence tomography angiography

      Reference database of total retinal vessel surface area derived from volume-rendered optical coherence tomography angiography

      Optical coherence tomography angiography (OCTA) enables three-dimensional, high-resolution, depth-resolved flow to be distinguished from non-vessel tissue signals in the retina. Thus, it enables the quantification of the 3D surface area of the retinal vessel signal. Despite the widespread use of OCTA, no representative spatially rendered reference vessel surface area data are published. In this study, the OCTA vessel surface areas in 203 eyes of 107 healthy participants were measured in the 3D domain. A Generalized Linear Model (GLM) model analysis was performed to investigate the effects of sex, age, spherical equivalent, axial length, and visual acuity on the OCTA vessel ...

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    4. Dynamic volume-rendered optical coherence tomography pupillometry

      Dynamic volume-rendered optical coherence tomography pupillometry

      Purpose: To assess intrapupillary space (IPS) changes in healthy subjects with regard to decreased iris motility in patients with pseudoexfoliation glaucoma (PEXG) or non-arteritic anterior ischaemic optic neuropathy (NAION) in a feasibility study in a clinical environment. Methods: Scotopic and photopic IPS measurements using three-dimensionally rendered swept-source optical coherence tomography (SS-OCT) data were obtained and compared for all subjects. Intrapupillary space (IPS) parameters were evaluated such as absolute volumetric differences, relative light response for volumetric ratios and pupillary ejection fraction (PEF) for functional contraction measurements. Results: From a total of 122 IPS from 66 subjects, 106 IPS were eligible for ...

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    5. Uncovering of intraspecies macular heterogeneity in cynomolgus monkeys using hybrid machine learning optical coherence tomography image segmentation

      Uncovering of intraspecies macular heterogeneity in cynomolgus monkeys using hybrid machine learning optical coherence tomography image segmentation

      The fovea is a depression in the center of the macula and is the site of the highest visual acuity. Optical coherence tomography (OCT) has contributed considerably in elucidating the pathologic changes in the fovea and is now being considered as an accompanying imaging method in drug development, such as antivascular endothelial growth factor and its safety profiling. Because animal numbers are limited in preclinical studies and automatized image evaluation tools have not yet been routinely employed, essential reference data describing the morphologic variations in macular thickness in laboratory cynomolgus monkeys are sparse to nonexistent. A hybrid machine learning algorithm ...

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    1-5 of 5
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  2. Topics in the News

    1. (1 articles) University of Freiburg
    2. (1 articles) University College London
    3. (1 articles) Heidelberg Engineering
    4. (1 articles) Columbia University
    5. (1 articles) University of Rochester
    6. (1 articles) Stanford University
    7. (1 articles) Johns Hopkins University
    8. (1 articles) National University of Singapore
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    Uncovering of intraspecies macular heterogeneity in cynomolgus monkeys using hybrid machine learning optical coherence tomography image segmentation Dynamic volume-rendered optical coherence tomography pupillometry Reference database of total retinal vessel surface area derived from volume-rendered optical coherence tomography angiography Imaging the Vitreous with a Novel Boosted Optical Coherence Tomography Technique: Vitreous Degeneration and Cisterns Imaging the Vitreous with a Novel Boosted Optical Coherence Tomography Technique: Posterior Vitreous Detachment Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea Optical coherence tomography image based eye disease detection using deep convolutional neural network Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema After Dexamethasone Implants Macular and Optic Disc Parameters in Children with Amblyopic and Nonamblyopic Eyes under Optical Coherence Tomography Fundus Images Optical coherence tomography assessment of the enamel surface after debonding the ceramic brackets using three different techniques Schizophrenia in Translation: Why the Eye?