1. Articles from Guofu Huang

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    1. Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography

      Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography

      Biomechanical properties of corneal scar are strongly correlated with many corneal diseases and some types of corneal surgery, however, there is no elasticity information available about corneal scar to date. Here, we proposed an acoustic radiation force optical coherence elastography system to evaluate corneal scar elasticity. Elasticity quantification was first conducted on ex vivo rabbit corneas, and the results validate the efficacy of our system. Then, experiments were performed on an ex vivo human scarred cornea, where the structural features, the elastic wave propagations, and the corresponding Young's modulus of both the scarred region and the normal region were ...

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    2. A preliminary study of shaker-based optical coherence elastography for assessment of gingival elasticity

      A preliminary study of shaker-based optical coherence elastography for assessment of gingival elasticity

      Studies on the changes in biomechanical properties of the gingiva are significant, since they are closely related to the pathological process of gingivitis and periodontitis. Although some research has been conducted, the currently used techniques are not feasible for in vivo and clinical measurements due to their disadvantages, such as the invasive nature and the requirement of thin sectioning. In this study, we developed a shaker-based optical coherence elastography system which provides noninvasive measurement, high axial resolution, high displacement sensitivity, and real-time imaging, and explored its potential for the detection of gingival elasticity. The system was tested by an agar ...

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    A preliminary study of shaker-based optical coherence elastography for assessment of gingival elasticity Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography Vascular Response of Orsiro vs. Xience Drug-Eluting Stents for Treating Coronary Bifurcation Lesions Trojan-Horse Diameter-Reducible Nanotheranostics for Macroscopic/Microscopic Imaging-Monitored Chemo-Antiangiogenic Therapy Prediction of Neoplastic Progression in Barrett’s Esophagus Using Nanoscale Nuclear Architecture Mapping: A Pilot Study Thickness of retinal pigment epithelium–Bruch’s membrane complex in adult Chinese using optical coherence tomography Interocular symmetry of optical coherence tomography parameters in healthy children and adolescents Fluorescein Leakage and Optical Coherence Tomography Angiography Features of Microaneurysms in Diabetic Retinopathy Cross-free in both lateral and axial directions Fourier-domain full-field optical coherence tomography Microperimetry, Humphrey field analyzer, and optical coherence tomography in detecting glaucoma: a comparative performance study Scanning optimization of an electrothermally-actuated MEMS mirror for applications in optical coherence tomography endoscopy Near-infrared active superparamagnetic iron oxide nanoparticles for magnetomotive optical coherence tomography imaging and magnetic hyperthermia therapeutic applications