1. Articles from Christopher G. Lui

    1-2 of 2
    1. Endolymphatic Hydrops is a Marker of Synaptopathy Following Traumatic Noise Exposure

      Endolymphatic Hydrops is a Marker of Synaptopathy Following Traumatic Noise Exposure

      After acoustic trauma, there can be loss of synaptic connections between inner hair cells and auditory neurons in the cochlea, which may lead to hearing abnormalities including speech-in-noise difficulties, tinnitus, and hyperacusis. We have previously studied mice with blast-induced cochlear synaptopathy and found that they also developed a build-up of endolymph, termed endolymphatic hydrops. In this study, we used optical coherence tomography to measure endolymph volume in live CBA/CaJ mice exposed to various noise intensities. We quantified the number of synaptic ribbons and postsynaptic densities under the inner hair cells 1 week after noise exposure to determine if they ...

      Read Full Article
    2. In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device

      In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device

      We describe an optical coherence tomography and vibrometry system designed for portable hand-held usage in the otology clinic on awake patients. The system provides clinically relevant point-of-care morphological imaging with 14-44 µm resolution and functional vibratory measures with sub-nanometer sensitivity. We evaluated various new approaches for extracting functional information including a multi-tone stimulus, a continuous chirp stimulus, and alternating air and bone stimulus. We also explored the vibratory response over an area of the tympanic membrane (TM) and generated TM thickness maps. Our results suggest that the system can provide real-time in vivo imaging and vibrometry of the ear and ...

      Read Full Article
    1-2 of 2
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (2 articles) University of Southern California
    2. (2 articles) Heidelberg Engineering
    3. (1 articles) Northwestern University
    4. (1 articles) Jichi Medical University
    5. (1 articles) Stanford University
    6. (1 articles) University of Florence
    7. (1 articles) Centre Hospitalier Intercommunal de Créteil
    8. (1 articles) University of Montreal
    9. (1 articles) Peking University
    10. (1 articles) Hanyang University
    11. (1 articles) University of Toronto
    12. (1 articles) Carl Zeiss Meditec
  3. Popular Articles

  4. Picture Gallery

    In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device Endolymphatic Hydrops is a Marker of Synaptopathy Following Traumatic Noise Exposure The truth about invisible posterior vitreous structures The Influence of Eyelid Position and Environmental Conditions on the Corneal Changes in Early Postmortem Interval: A Prospective, Multicentric OCT Study The Use of Optical Coherence Tomography for Gross Examination and Sampling of Fixed Breast Specimens: A Pilot Study The Role of Widefield and Ultra Widefield Optical Coherence Tomography in the Diagnosis and Management of Vitreoretinal Diseases Acute Idiopathic Blind Spot Enlargement Syndrome-New Perspectives in the OCT Era Longitudinal Comparison of Constant Artifacts in Optical Coherence Tomography Angiography in Patients with Posterior Uveitis Compared to Healthy Subjects Choriocapillaris Flow Deficits Quantification in Hydroxychloroquine Retinopathy Using Swept-Source Optical Coherence Tomography Angiography Swept-Source OCT Angiography Features in Patients after Macular Hole Surgery Early OCTA Changes of Type 3 Macular Neovascularization Following Brolucizumab Intravitreal Injections Distribution Pattern of Total Corneal Thickness in Keratoconus versus Normal Eyes Using an Optical Coherence Tomography