1. Articles from Jason Chan

    1-4 of 4
    1. Clinically relevant factors associated with a binary outcome of diabetic macular ischaemia: an OCTA study

      Clinically relevant factors associated with a binary outcome of diabetic macular ischaemia: an OCTA study

      Aims We investigated the demographic, ocular, diabetes-related and systemic factors associated with a binary outcome of diabetic macular ischaemia (DMI) as assessed by optical coherence tomography angiography (OCTA) evaluation of non-perfusion at the level of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in a cohort of patients with diabetes mellitus (DM). Materials and methods 617 patients with DM were recruited from July 2015 to December 2020 at the Chinese University of Hong Kong Eye Centre. Image quality assessment (gradable or ungradable for assessing DMI) and DMI evaluation (presence or absence of DMI) were assessed at the level ...

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    2. A multi-task deep-learning system for assessment of diabetic macular ischemia on optical coherence tomography angiography images

      A multi-task deep-learning system for assessment of diabetic macular ischemia on optical coherence tomography angiography images

      Purpose: We aimed to develop and test a deep-learning (DL) system to perform image quality and diabetic macular ischemia (DMI) assessment on OCTA images. Methods: This study included 7,194 OCTA images with diabetes mellitus for training and primary validation, and 960 images from three independent datasets for external testing. A trinary classification for image quality assessment and presence or absence of DMI for DMI assessment were labelled on all OCTA images. Two DenseNet-161 models were built for both tasks for OCTA images of superficial and deep capillary plexus, respectively. External testing was performed on three unseen datasets in which ...

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    3. A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis

      A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis

      OBJECTIVE Diabetic macular edema (DME) is the primary cause of vision loss among individuals with diabetes mellitus (DM). We developed, validated, and tested a deep learning (DL) system for classifying DME using images from three common commercially available optical coherence tomography (OCT) devices. RESEARCH DESIGN AND METHODS We trained and validated two versions of a multitask convolution neural network (CNN) to classify DME (center-involved DME [CI-DME], non-CI-DME, or absence of DME) using three-dimensional (3D) volume scans and 2D B-scans, respectively. For both 3D and 2D CNNs, we used the residual network (ResNet) as the backbone. For the 3D CNN, we ...

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    4. Topical prostaglandin analogue use and cystoid macular oedema following uneventful cataract surgery: a randomised control trial

      Topical prostaglandin analogue use and cystoid macular oedema following uneventful cataract surgery: a randomised control trial

      Background/aims The association between the development of cystoid macular oedema (CMO) following uneventful cataract surgery and prostaglandin analogue (PGA) therapy has not been fully determined. The study aim was to investigate whether discontinuation of PGA therapy following uneventful cataract surgery affected the incidence of postoperative CMO. Methods A prospective randomised controlled trial of 62 eyes of 62 participants with ocular hypertension (OH) or primary open angle glaucoma (POAG) treated with PGAs prior to cataract surgery. Participants were randomised to continue with PGA therapy after cataract surgery (CPGA) (n=31) or to discontinue PGA therapy (n=31). The primary outcome ...

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    1-4 of 4
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    1. (2 articles) The Chinese University of Hong Kong
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    Topical prostaglandin analogue use and cystoid macular oedema following uneventful cataract surgery: a randomised control trial A Multitask Deep-Learning System to Classify Diabetic Macular Edema for Different Optical Coherence Tomography Devices: A Multicenter Analysis A multi-task deep-learning system for assessment of diabetic macular ischemia on optical coherence tomography angiography images Clinically relevant factors associated with a binary outcome of diabetic macular ischaemia: an OCTA study Editorial – Optical Coherence Tomography Angiography: Considerations Regarding Diagnostic Parameters Imaging of the optic nerve: technological advances and future prospects Optical coherence tomography assessment of pulmonary vascular remodeling in advanced heart failure. The OCTOPUS-CHF study Systems and methods for automated widefield optical coherence tomography angiography OCT signal processing device and recording medium Application of optical coherence tomography angiography to assess systemic severity in patients with hereditary transthyretin amyloidosis Detection of pachychoroid neovasculopathy with optical coherence tomography angiography versus dye angiography imaging Optical Coherence Tomography-Based Choroidal Structural Analysis and Vascularity Index in Best Vitelliform Macular Dystrophy