1. Quantification of microbubbles in blood with phase-sensitive SSOCT

    Explore Article SPIE Digital Library (Feb 23 2010)

    Quantification of microbubbles in blood with phase-sensitive SSOCT We have developed a phase stabilized swept source optical coherence tomography (PhS-SSOCT), that shows an axial resolution of 10 µm, phase sensitivity of 0.04 radians, imaging depth of up to 6 mm in air and a scanning speed of 20 kHz for a single A-line. In this paper, the PhS-SSOCT is applied to quantify gas microbubbles in blood in vitro. The results indicate that the system is able to detect bubbles of diameters greater than 10 µm using the structural image and the microbubbles of diameter less than 10 µm could be detected using the temporal phase response. Images of ... (Read Full Article)

    Comment on Article Mentions:   Kirill V. Larin   University of Houston

  2. Phase-sensitive swept source optical coherence tomography for imaging and quantifying of microbubbles in clear and scattering media

    Explore Article Scitation (May 20 2009)

    phase resolved system based on swept source optical coherence tomography (SSOCT) called as phase-sensitive SSOCT to detect and quantify gas microbubbles in aqueous and tissue simulated media is developed. The structural images of gas microbubbles are obtained using conventional SSOCT, while common path SSOCT was used to perform the phase-sensitive measurements. The system shows an axial resolution of 10 µm, a phase sensitivity of 0.03 rad, an imaging depth of up to 6 mm in air, and a scanning speed of 20 kHz for a single A-line. The structural images of the bubbles show an accuracy of 10 µm, whereas ... (Read Full Article)

    Comment on Article Mentions:   Kirill V. Larin   University of Houston   Saratov State University

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