1. Articles from Moshe Y. Bressler

    1-3 of 3
    1. Transforming the treatment of psoriasis to the 21st century: Detecting subclinical therapeutic response to secukinumab using optical coherence tomography as a prognostic indicator

      Transforming the treatment of psoriasis to the 21st century: Detecting subclinical therapeutic response to secukinumab using optical coherence tomography as a prognostic indicator

      Background: Optical coherence tomography (OCT) is a noninvasive imaging device that scans the skin up to 2 mm in depth. OCT can capture real-time epidermal thickness (ET) measurements and detect subclinical changes in inflammatory skin diseases like eczema and psoriasis. © 2022 Wiley Periodicals LLC. Objective: To determine if measuring ET with OCT can detect a subclinical therapeutic response in psoriasis treated with the biological therapy, secukinumab (an IL-17A antagonist). Design: Phase IV, single-center, open-label, and single-arm study. Participants: Twenty-six consecutive patients with moderate to severe plaque psoriasis. Measurements: Clinical, dermoscopic, and OCT images were obtained at each visit. The clinician ...

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    2. Combining Nd:YAG laser with optical coherence tomography for nonsurgical treatment of basal cell carcinoma

      Combining Nd:YAG laser with optical coherence tomography for nonsurgical treatment of basal cell carcinoma

      Background: Effective and aesthetically appealing management options are needed for basal cell carcinoma (BCC), the most common skin cancer. The Nd:YAG laser shows promise, but most studies use biopsy to demonstrate tumor clearance. Optical coherence tomography (OCT) could allow good tumor margin control while enabling recurrence monitoring. Objective: Determine the efficacy of the Nd:YAG laser to treat BCCs while controlling for tumor margin with OCT. Methods: A 1064-nm Nd:YAG laser was applied to treat 119 BCCs in 102 patients, where tumor margins were approximated using OCT. Lesions were treated every 2 months until no residual tumor remained ...

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    3. Combining Reflective Confocal Microscopy and Dynamic Optical Coherence Tomography to Diagnose Melanoacanthoma: Case Report

      Combining Reflective Confocal Microscopy and Dynamic Optical Coherence Tomography to Diagnose Melanoacanthoma: Case Report

      Few reported cases discuss distinguishing between melanoma and melanoacanthoma , a seborrheic keratosis (SK) variant, using noninvasive imaging devices. We present a case of a 38-year-old man with Fitzpatrick skin type IV with an asymmetric black papule showing clinical and dermoscopic features of both melanoma and SK. Reflectance confocal microscopy (RCM) and dynamic optical coherence tomography (d-OCT) were used for further evaluation. RCM revealed acanthotic epidermis with a mixed honeycomb and cobblestone pattern, polycyclic bulbous rete ridges, and bright plump cells within entrapped, edged, dermal papillae, compatible with pigmented SK. Also noted were a population of fairly uniform bright dendritic cells ...

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    1-3 of 3
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    1. (1 articles) Mount Sinai School of Medicine
    2. (1 articles) University of Houston
    3. (1 articles) Cardiovascular Research Foundation
    4. (1 articles) Vanderbilt University
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    6. (1 articles) Tokyo Medical & Dental University
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    Combining Reflective Confocal Microscopy and Dynamic Optical Coherence Tomography to Diagnose Melanoacanthoma: Case Report Combining Nd:YAG laser with optical coherence tomography for nonsurgical treatment of basal cell carcinoma Transforming the treatment of psoriasis to the 21st century: Detecting subclinical therapeutic response to secukinumab using optical coherence tomography as a prognostic indicator Macular and choroidal perfusion using optical coherence tomography angiography in type-2 diabetic patients without diabetic retinopathy Short-term evaluation of clear corneal incision after phacoemulsification using anterior segment optical coherence tomography Evaluation of the central vault following implantable phakic contact lens and its correlation to horizontal white to white corneal diameter by anterior segment optical coherence tomography Automatic bifurcation detection utilizing pullback characteristics of bifurcation in intravascular optical coherence tomography An IoT based predictive modeling for Glaucoma detection in optical coherence tomography images using hybrid genetic algorithm The Value of Optical Coherence Tomography Angiography in Pituitary Adenomas Effectiveness of optical coherence tomography angiography (OCT-A) in staging glaucoma Quantitative dynamic cellular imaging based on 3d unwrapped optical coherence phase microscopyoptical coherence phase microscopy (Thesis) The use of OCT to detect signs of intracranial hypertension in patients with sagittal suture synostosis: Reference values and correlations