1. Articles from a. podoleanu

    1-6 of 6
    1. Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source

      Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source

      We report on the use of a single supercontinuum (SC) source for multimodal imaging. The 2-octave bandwidth (475–2300 nm) makes the SC source suitable for optical coherence tomography (OCT) as well as for multispectral photoacoustic microscopy (MPAM). The IR band centered at 1310 nm is chosen for OCT to penetrate deeper into tissue with 8 mW average power on the sample. The 500–840 nm band is used for MPAM. The source has the ability to select the central wavelength as well as the spectral bandwidth. An energy of more than 35 nJ within a less than 50 nm ...

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    2. Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

      Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

      Supercontinuum (SC) sources are of great interest for many applications due to their ultra-broad optical bandwidth, good beam quality and high power spectral density [1]. In particular, the high average power over large bandwidths makes SC light sources excellent candidates for ultra-high resolution optical coherence tomography (UHR-OCT) [2-5]. However, conventional SC sources suffer from high pulse-to-pulse intensity fluctuations as a result of the noise-sensitive nonlinear effects involved in the SC generation process [6-9]. This intensity noise from the SC source can limit the performance of OCT, resulting in a reduced signal-to-noise ratio (SNR) [10-12]. Much work has been done to ...

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    3. A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography at 1300 nm

      A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography at 1300 nm

      Supercontinuum (SC) light is a well-established technology, which finds applications in several domains ranging from chemistry to material science and imaging systems [1-2]. More specifically, its ultra-wide optical bandwidth and high average power make it an ideal tool for Optical Coherence Tomography (OCT). Over the last 5 years, numerous examples have demonstrated its high potential [3-4] in this context. However, SC light sources present pulse-to-pulse intensity variation that can limit the performance of any OCT system [5] by degrading their signal to noise ratio (SNR). To this goal, we have studied and compared the noise of several SC light sources ...

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    4. Spectroscopic low coherence interferometry using a supercontinuum source and an ultra broadband spectrometer

      Spectroscopic low coherence interferometry using a supercontinuum source and an ultra broadband spectrometer

      Spectroscopic optical coherence tomography (SOCT) combines the imaging capability of optical coherence tomography with spectroscopic absorption information. SOCT requires a large bandwidth combined with a broadband spectrometer, due to the processing of the measured data, which includes dividing the spectrum in spectral bands. Both, spectral and axial resolution of SOCT depend on the spectral width of each window. A supercontinuum source with its broad spectrum allows a sufficient number of windows combined with a reasonable axial resolution, which depends on the application. Here a SOCT system is used in the visible spectral range from 480 to 730 nm by combining ...

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    5. Imaging of periocular basal cell carcinoma using en face optical coherence tomography: a pilot study

      Imaging of periocular basal cell carcinoma using en face optical coherence tomography: a pilot study
      Aim To use en face optical coherence tomographic (OCT) imaging to identify features of tumour tissue and their correlation with histopathologic findings and to assess the effect of different wavelengths and resolutions of OCT in identifying tumour boundaries and features. Methods Excision specimens of consecutive biopsy-proven periocular basal cell carcinomas (BCCs) (n=8) were assessed by OCT, performing in vitro cross-section and en face scans of the tissues. Images were collected from three different machines: systems 1 and 2 had a wavelength of 1300 nm, and system 3 had a wavelength of 840 nm. System 2 used high numerical aperture ...
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    6. Combining confocal microscopy and optical coherence tomography for imaging in developmental biology

      A. Bradu, Lisha Ma, J. Bloor et al. In-vivo Optical Coherence Tomography (OCT) imaging of the fruit fly Drosophila melanogaster larval heart allows non invasive visualizations and assesment of its cardiac functions. To image Drosophila melanogaster heart, we have developed a dedicated imaging instrument able to provide simultaneous Op ... [Proc. SPIE Int. Soc. Opt. Eng. 6991, 69910K (2008)] published Fri May 2, 2008.
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    1-6 of 6
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    1. (6 articles) University of Kent
    2. (6 articles) Adrian G. Podoleanu
    3. (3 articles) NKT Photonics
    4. (2 articles) Adrian Bradu
    5. (1 articles) Technical University of Denmark (DTU)
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    Imaging of periocular basal cell carcinoma using en face optical coherence tomography: a pilot study Spectroscopic low coherence interferometry using a supercontinuum source and an ultra broadband spectrometer A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography at 1300 nm Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm Multispectral photoacoustic microscopy and optical coherence tomography using a single supercontinuum source In vivo dynamic characterization of the human tympanic membrane using pneumatic optical coherence tomography Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography Spectral Domain – Optical Coherence Tomography findings in Triple-A Syndrome – A case series from Pakistan Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty A preliminary study of post-progressive nail-art effects on in vivo nail plate using optical coherence tomography-based intensity profiling assessment Analysis of the Choroid and Its Relationship with the Outer Retina in Patients with Diabetes Mellitus Using Binarization Techniques Based on Spectral-Domain Optical Coherence Tomography Quantifying the Pattern of Retinal Vascular Orientation in Diabetic Retinopathy Using Optical Coherence Tomography Angiography