1. Articles from Michael A. Restaino

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    1. Direct laser writing of a titanium dioxide-laden retinal cone phantom for adaptive optics-optical coherence tomography

      Direct laser writing of a titanium dioxide-laden retinal cone phantom for adaptive optics-optical coherence tomography

      The spatial resolution of adaptive optics-optical coherence tomography (AO-OCT) enables visualization of retinal components ( e.g ., photoreceptors), which can advance clinical diagnosis of ocular diseases. Currently, however, variability in AO-OCT system performance suggests a need for standardized physical models, or “phantoms”, that replicate the opto-structural properties of retinal components. Here we employ direct laser writing – a two-photon polymerization-based additive manufacturing technology – using a light scattering titanium (IV) dioxide nanoparticle-laden photomaterial to create novel retinal cone outer segment (OS) phantoms. Fabrication results demonstrate effective mimicry of cone OS diameter and spacing at four retinal eccentricities, while AO-OCT experiments demonstrate cone spacings ...

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    1. (1 articles) University of Maryland
    2. (1 articles) FDA
    3. (1 articles) Tufts University
    4. (1 articles) UCLA
    5. (1 articles) Universidade Federal de São Paulo
    6. (1 articles) University of Auckland
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    8. (1 articles) Xuan Liu
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