1. Articles from Maxwell Pistilli

    1-3 of 3
    1. Evaluation of the Cirrus HD-OCT Normative Database Probability Codes in an African American Population

      Evaluation of the Cirrus HD-OCT Normative Database Probability Codes in an African American Population

      Objective: Race-adjusted interpretation of data from Cirrus high-definition optical coherence tomography (HD-OCT) devices is not standard practice. The aim of this study is to evaluate differences in peripapillary retinal nerve fiber layer (RNFL) thickness between healthy African Americans and the Cirrus HD-OCT normative database. Design: This is a cross-sectional observational study using control patients recruited from the greater Philadelphia, Pennsylvania area. Subjects: A total of 466 eyes were included in this study. Subjects were retrospectively identified from the control cohort of the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study. Methods: Using an age-stratified or linear regression method, we reclassified ...

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    2. Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials

      Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials

      Purpose To identify precursors of macular atrophy (MA) and of fibrotic scar (FS) in eyes treated with anti-VEGF through pixel-mapping analysis of baseline OCT. Design Cross-sectional analysis. Setting Multicenter clinical trial. Patient population 68 eyes from the Comparison of Age-Related Macular Degeneration Treatments Trials. Intervention Treatment with anti-VEGF agents. Main outcome measure The percentage of MA or FS pixels with each OCT feature at baseline, and the odds ratio (OR) for baseline pixels with an OCT feature to develop MA or FS. Results RPE atrophy and photoreceptor loss on OCT were highly predictive of MA at that location at years ...

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      Mentions: Duke University
    3. Utility of Spectral-Domain Optical Coherence Tomography in Differentiating Papilledema From Pseudopapilledema: A Prospective Longitudinal Study

      Utility of Spectral-Domain Optical Coherence Tomography in Differentiating Papilledema From Pseudopapilledema: A Prospective Longitudinal Study

      Background: Prospective and longitudinal studies assessing the utility of spectral-domain optical coherence tomography (SD-OCT) to differentiate papilledema from pseudopapilledema are lacking. We studied the sensitivity and specificity of baseline and longitudinal changes in SD-OCT parameters with 3D segmentation software to distinguish between papilledema and pseudopapilledema in a cohort of patients referred for evaluation of undiagnosed optic disc elevation. Methods: Fifty-two adult patients with optic disc elevation were enrolled in a prospective longitudinal study. A diagnosis of papilledema was made when there was a change in the appearance of the optic disc elevation on fundus photographs as noted by an independent ...

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    1-3 of 3
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    Utility of Spectral-Domain Optical Coherence Tomography in Differentiating Papilledema From Pseudopapilledema: A Prospective Longitudinal Study Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials Evaluation of the Cirrus HD-OCT Normative Database Probability Codes in an African American Population Vascular and Structural Alterations of the Choroid Evaluated by Optical Coherence Tomography Angiography and Enhanced-Depth Imaging Optical Coherence Tomography in Eyes with Reticular Pseudodrusen and Soft Drusen Total venous nature of retinal deep capillary plexus inferred by continuity of prominent middle limiting membrane sign in optical coherence tomography Evaluating Onychomycosis Outcomes 2 Months into an 11-month-long Efinaconazole Regimen: The Role of Optical Coherence Tomography Accuracy of Common Motion Estimators in Wave-Based  Optical Coherence Elastography Quantitative evaluation of the dynamic activity of HeLa cells in different viability states using dynamic full-field optical coherence microscopy A New Method for Automating the Diagnostic Analysis of Human Fundus Images Obtained Using Optical Coherent Tomography Angiography Quantifying Retinal Microvascular Morphology in Schizophrenia Using Swept-Source Optical Coherence Tomography Angiography In vivo examination of healthy human skin after short-time treatment with moisturizers using confocal Raman spectroscopy and optical coherence tomography: Preliminary observations Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography