1. Articles from Zhen Ling Teo

    1-3 of 3
    1. Normative data and associations of Optical Coherence Tomography Angiography measurements of the macula: The Singapore Malay Eye Study

      Normative data and associations of Optical Coherence Tomography Angiography measurements of the macula: The Singapore Malay Eye Study

      Objective: To describe the normative quantitative parameters of macular retinal vasculature and their systemic and ocular associations, using optical coherence tomography angiography (OCTA). Design: Population based cross sectional study SUBJECTS: Adults above 50 years old were recruited from the third examination of the population-based Singapore Malay Eye Study. Methods: All participants underwent standardized comprehensive examination and Spectral domain-OCTA (Optovue, USA) of the macula. OCTA scans with pre-existing retinal disease, macular pathology, and poor quality were excluded. Main outcome measures: Normative quantitative vessel densities of the superficial, deep layer and foveal avascular zone were evaluated. Ocular and systemic associations with macular ...

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    2. Computer-aided detection and abnormality score for the outer retinal layer in optical coherence tomography

      Computer-aided detection and abnormality score for the outer retinal layer in optical coherence tomography

      Background: To develop computer-aided detection (CADe) of ORL abnormalities in the retinal pigmented epithelium, interdigitation zone and ellipsoid zone via optical coherence tomography (OCT). Methods: In this retrospective study, healthy participants with normal ORL, and patients with abnormality of ORL including choroidal neovascularisation (CNV) or retinitis pigmentosa (RP) were included. First, an automatic segmentation deep learning (DL) algorithm, CADe, was developed for the three outer retinal layers using 120 handcraft masks of ORL. This automatic segmentation algorithm generated 4000 segmentations, which included 2000 images with normal ORL and 2000 (1000 CNV and 1000 RP) images with focal or wide defects ...

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    3. Detection of features associated with neovascular age-related macular degeneration in ethnically distinct data sets by an optical coherence tomography: trained deep learning algorithm

      Detection of features associated with neovascular age-related macular degeneration in ethnically distinct data sets by an optical coherence tomography: trained deep learning algorithm

      Background The ability of deep learning (DL) algorithms to identify eyes with neovascular age-related macular degeneration (nAMD) from optical coherence tomography (OCT) scans has been previously established. We herewith evaluate the ability of a DL model, showing excellent performance on a Korean data set, to generalse onto an American data set despite ethnic differences. In addition, expert graders were surveyed to verify if the DL model was appropriately identifying lesions indicative of nAMD on the OCT scans. Methods Model development data set—12 247 OCT scans from South Korea; external validation data set—91 509 OCT scans from Washington, USA ...

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    1-3 of 3
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    1. (2 articles) Singapore Eye Research Institute
    2. (2 articles) Yonsei University
    3. (2 articles) National University of Singapore
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    Detection of features associated with neovascular age-related macular degeneration in ethnically distinct data sets by an optical coherence tomography: trained deep learning algorithm Computer-aided detection and abnormality score for the outer retinal layer in optical coherence tomography Normative data and associations of Optical Coherence Tomography Angiography measurements of the macula: The Singapore Malay Eye Study Peripapillary Vessel Density in Relation to Optic Disc Drusen: A Multimodal Optical Coherence Tomography Study Repeatability and reliability of semi-automated anterior segment-optical coherence tomography imaging compared to manual analysis in normal and keratoconus eyes Imaging of choroidal neovascular membrane by optical coherence tomography Angiography Image enhancement of wide-field retinal optical coherence tomography angiography by super-resolution angiogram reconstruction generative adversarial network Seven Fractures in Three Second Generation Drug Eluting Stents Implanted in the Right Coronary Artery Assessed by Using Optical Coherence Tomography Following the Beat: Imaging the Valveless Pumping Function in the Early Embryonic Heart Mirau-based line-field confocal optical coherence tomography for three-dimensional high-resolution skin imaging Optical Coherence Tomography Findings in Choroidal Melanoma-Associated Subretinal Fluid Evaluation of retinal vessel and perfusion density in migraine patients by optical coherence tomography angiography