1. Articles from Andreas Schlatter

    1-3 of 3
    1. Effect of hyperoxia and hypoxia on retinal vascular parameters assessed with optical coherence tomography angiography

      Effect of hyperoxia and hypoxia on retinal vascular parameters assessed with optical coherence tomography angiography

      Purpose: To investigate the response of the superficial and deep capillary plexuses to hyperoxia and hypoxia using optical coherence tomography angiography (OCT-A) and retinal vessel analyzer. Methods: Twenty-four healthy volunteers participated in this randomized, double-masked, cross-over study. For each subject, two study days were scheduled: on one study day, hyperoxia was induced by breathing 100% oxygen whereas on the other study day, hypoxia was induced by breathing a mixture of 88% nitrogen and 12% oxygen. Perfusion density was calculated in the superficial vascular plexus (SVP) and the deep capillary plexus (DCP), using OCT-A before (normal breathing) and during breathing of ...

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    2. Plexus-Specific Effect of Flicker-Light Stimulation on the Retinal Microvasculature Assessed with Optical Coherence Tomography Angiography

      Plexus-Specific Effect of Flicker-Light Stimulation on the Retinal Microvasculature Assessed with Optical Coherence Tomography Angiography

      In neural tissues, the coupling between neural activity and blood flow is a physiological key principle in blood flow regulation. We used optical coherence tomography angiography to investigate stimulus-evoked hemodynamic responses in different microvascular layers of the human retina. Twenty-two healthy subjects were included. Vessel density before and during light stimulation was measured using optical coherence tomography angiography and assessed for the superficial, intermediate and deep capillary plexus of the retinal circulation. Volumetric blood flow was measured using a custom-built Doppler optical coherence tomography system. Our results show that flicker stimulation induced a significant increase in the vessel density of ...

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    3. Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease

      Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease

      Imaging has become indispensable in the diagnosis and management of diseases in the posterior part of the eye. In recent years, imaging techniques for the anterior segment are also gaining importance and are nowadays routinely used in clinical practice. Ocular surface disease is often synonymous with dry eye disease, but also refers to other conditions of the ocular surface, such as Meibomian gland dysfunction or keratitis and conjunctivitis with different underlying causes, i.e., allergies or infections. Therefore, correct differential diagnosis and treatment of ocular surface diseases is crucial, for which imaging can be a helpful tool. A variety of ...

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    1-3 of 3
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    1. (2 articles) Medical University of Vienna
    2. (1 articles) Singapore Eye Research Institute
    3. (1 articles) Nanyang Technological University
    4. (1 articles) Northwestern University
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    Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease Plexus-Specific Effect of Flicker-Light Stimulation on the Retinal Microvasculature Assessed with Optical Coherence Tomography Angiography Effect of hyperoxia and hypoxia on retinal vascular parameters assessed with optical coherence tomography angiography Influence of scan direction on subfoveal choroidal vascularity index using optical coherence tomography Subthreshold Nanosecond Laser for Non-resolving Central Serous Chorioretinopathy: A Double-masked Sham-controlled Randomised Trial Optical Coherence Tomography Angiography (OCTA) to Assess Cardiac Output and Cerebral Perfusion at the Time of Children's Cardiac Surgery Recent advances in optical coherence tomography for anterior segment imaging in small animals and their clinical implications Intraoperative optical coherence tomography-guided donor corneal tissue assessment and preparation Peripapillary and fovea avascular zone optical coherence tomography angiography parameters in exfoliation glaucoma versus primary open-angle glaucoma versus healthy eyes Comparison of the proposed DCNN model with standard CNN architectures for retinal diseases classification Massachusetts General Hosptial Receives NIH Grant for Screening for Barrett's Esophagus Progressors with Multimodality Tethered Capsule Image-Guided Biopsy Duke University Receives NIH Grant for Robotic Point-of-Care OCT