1. Articles from hiroki kato

    1-9 of 9
    1. Qualitative and Quantitative Assessment of Stent Restenosis by Optical Coherence Tomography

      Qualitative and Quantitative Assessment of Stent Restenosis by Optical Coherence Tomography

      We hypothesized that the tissue components of in-stent restenosis (ISR) might differ between drug-eluting stents (DES) and bare-metal stents (BMS) and that these differences could be distinguished by qualitative and quantitative optical coherence tomography (OCT) analyses. Methods and Results:  One-hundred and twenty-two initial ISR lesions (sirolimus-eluting stents: n=28; paclitaxel-eluting stents: n=51; BMS: n=43) were evaluated with OCT. Based on their OCT appearance, the lesions were classified as homogeneous, layered or heterogeneous. The optical properties of backscatter, attenuation and signal intensity of the neointimal tissue (NIT) were quantified. To evaluate the vascular response after balloon angioplasty (BA), the ...

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    2. The Ability of Optical Coherence Tomography to Monitor Percutaneous Coronary Intervention: Detailed Comparison with Intravascular Ultrasound

      The Ability of Optical Coherence Tomography to Monitor Percutaneous Coronary Intervention: Detailed Comparison with Intravascular Ultrasound
      ABSTRACT: Background. We investigated the usefulness of optical coherence tomography (OCT) to evaluate vessel response after stent implantation by comparing with that of intravascular ultrasound (IVUS). Methods and Results. Eighteen cases undergoing percutaneous coronary intervention (PCI) who provided consent for both IVUS and OCT usage pre- and post-PCI procedure were enrolled. The lumen area at the distal site of the culprit lesion was smaller on OCT images than on IVUS images due to proximal vessel occlusion, whereas the lumen area at the proximal site of the lesion did not differ between OCT and IVUS images (distal site: 4.6 ± 2 ...
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    3. Comparison by Optical Coherence Tomography of Paclitaxel-Eluting Stents With Sirolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure: 6-Month Follow-up

      Comparison by Optical Coherence Tomography of Paclitaxel-Eluting Stents With Sirolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure: 6-Month Follow-up
      Differences between paclitaxel-eluting stents (PES) and sirolimus-eluting stent (SES) in neointimal proliferation under strictly matched conditions remain to be clarified by optical coherence tomography (OCT). Methods and Results: Between May and December 2007, 27 patients were implanted with a PES and a SES, randomized to either the proximal or distal site in a single coronary artery, and underwent follow-up angiography and OCT examination at 6 months. The frequency of vessel wall apposition with neointima was greater for PES than for SES (92.6% vs 85.8%, P<0.01). The median (25th, 75th percentiles) neointimal thickness (NIT) in PES was ...
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    4. Factors That Influence Measurements and Accurate Evaluation of Stent Apposition by Optical Coherence Tomography

      Factors That Influence Measurements and Accurate Evaluation of Stent Apposition by Optical Coherence Tomography
      kground: Factors influencing measurements and accurate evaluation of stent apposition by optical coherence tomography (OCT) are not established. Methods and Results: Phantom models of known luminal sizes and lengths were evaluated by OCT under various conditions and measurements were compared with actual values. Stents implanted into phantom models were examined by OCT to validate the measurement point on the stent strut surface for accurate evaluation of stent apposition. Strut thickness was measured at 3 points (midpoint, inner and outer surfaces of the stent shadow). The precision of OCT measurements of lumen diameter and area was satisfactory when the image wire ...
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    5. Local Determinants of Thrombus Formation Following Sirolimus-Eluting Stent Implantation Assessed by Optical Coherence Tomography

      Objectives We conducted this study to assess the prevalence and determinants of subclinical thrombus after sirolimus-eluting stent (SES) implantation. Background Angioscopic analyses have demonstrated the presence of thrombus is more common than the clinical incidence of SES thrombosis. Methods Fifty-three patients (53 lesions) underwent 6-month follow-up optical coherence tomography. A stent eccentricity index ([SEI] minimum/maximum stent diameter) was determined in each cross section. To evaluate unevenness of neointimal thickness, a neointimal unevenness score ([NUS] maximum neointimal thickness in the cross section/average neointimal thickness of the same cross section) was calculated for each cross section. Average SEI and NUS ...
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    6. Low plasma adiponectin levels are associated with presence of thin-cap fibroatheroma in men with stable coronary artery disease

      Abstract: Background: Previous studies demonstrated the inverse association of adiponectin with coronary artery disease (CAD) especially in men with acute coronary syndrome, however their association with in vivo plaque vulnerability in stable CAD, which may be reflected by the thin-cap fibroatheroma (TCFA) prevalence, remains unknown.Methods: In 50 men with stable CAD, we identified TCFA with multi-vessel examination of combined use of virtual histology intravascular ultrasound (VH-IVUS) and optical coherence tomography (OCT). The definition of TCFA was described as follows; necrotic-core rich lesion (% necrotic-core >10%) without evidence of an overlying fibrous component and % plaque-volume >40% in at least 3 consecutive ...
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    7. Low Plasma Adiponectin Level and High Oxidative Stress are Associated with In Vivo Thin-Cap Fibroatheloma Prevalence in Patients with Stable Coronary Artery Disease

      Background; Few studies have investigated the association between biomarkers and in vivo plaque vulnerability in patients with stable coronary artery disease (CAD). Methods; We examined two or three vessels of 55 stable CAD patients with combined use of virtual histology intravascular ultrasound (VH-IVUS) and optical coherence tomography (OCT), and diagnosed thin-cap fibroatheroma (TCFA). The definition of TCFA was described as follow: necrotic core rich lesion (%necrotic-core>10%) without evident overlying fibrous component and %plaque-volume>40% by VH-IVUS analysis, and the thinnest fibrous-cap thickness
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    8. Very late thrombosis of sirolimus-eluting stent due to late malapposition: Serial observations with optical coherence tomography

      A 54 years old man underwent directional coronary atherectomy in segment 7 with a partial deep-cut injury. A sirolimus-eluting stent (SES) was implanted at the restenosed post-atherectomy lesion. Six months after SES implantation, intravascular ultrasound (IVUS) examination revealed slight vessel enlargement although there were no malapposed struts. Optical coherence tomography (OCT) revealed partial stent malapposition. Ticlopidine was discontinued 3 months after SES implantation, but aspirin was continued. Twenty-nine months after SES implantation, after discontinuing aspirin for 7 days for colon polypectomy, the patient suffered an acute myocardial infarction at the SES implantation site. IVUS revealed further positive vessel remodeling and ...
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    9. Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma

      Aims To evaluate the feasibility of the combined use of virtual histology (VH)-intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for detecting in vivo thin-cap fibroatheroma (TCFA). Methods and results In 56 patients with angina, 126 plaques identified by IVUS findings were analysed using both VH-IVUS and OCT. IVUS-derived TCFA was defined as an abundant necrotic core (>10% of the cross-sectional area) in contact with the lumen (NCCL) and %plaque-volume >40%. OCT-derived TCFA was defined as a fibrous cap thickness of Conclusion Neither modality alone is sufficient for detecting TCFA. The combined use of OCT and VH-IVUS might be ...
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    1-9 of 9
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    Factors That Influence Measurements and Accurate Evaluation of Stent Apposition by Optical Coherence Tomography Comparison by Optical Coherence Tomography of Paclitaxel-Eluting Stents With Sirolimus-Eluting Stents Implanted in One Coronary Artery in One Procedure: 6-Month Follow-up The Ability of Optical Coherence Tomography to Monitor Percutaneous Coronary Intervention: Detailed Comparison with Intravascular Ultrasound Qualitative and Quantitative Assessment of Stent Restenosis by Optical Coherence Tomography Intraoperative Optical Coherence Tomography in Idiopathic Macular Epiretinal Membrane Surgery Quantitative approaches in multimodal fundus imaging: State of the art and future perspectives Non-cystic macular thickening on optical coherence tomography as an alternative to fluorescein angiography for predicting retinal vascular leakage in early stages of uveitis Self-supervised patient-specific features learning for OCT image classification Accurate In Vivo Bowman's Thickness Measurement Using Mirau Ultrahigh Axial Resolution Line Field Optical Coherence Tomography Optical coherence tomography reveals retinal thinning in schizophrenia spectrum disorders Longitudinal Evaluation of Changes in Retinal Architecture Using Optical Coherence Tomography in Achromatopsia Large Amplitude Iris Fluttering Detected by Consecutive Anterior Segment Optical Coherence Tomography Images in Eyes with Intrascleral Fixation of an Intraocular Lens