1. Articles from Fan Fan

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    1. Optical Coherence Tomography Angiography for Mapping Cerebral Microvasculature Based on Normalized Differentiation Analysis

      Optical Coherence Tomography Angiography for Mapping Cerebral Microvasculature Based on Normalized Differentiation Analysis

      Optical coherence tomography angiography (OCTA) is a label‐free, noninvasive biomedical imaging modality for mapping microvascular networks and quantifying blood flow velocities in vivo . Simple computation and fast processing are critical for the OCTA in some applications. Herein, we report on a normalized differentiation method for mapping cerebral microvasculature with the advantages of simple analysis and high image quality, benefitting from computation of differentiation and characteristics of normalization. Normalized differentiation values are validated to have a nearly linear relationship with flow velocities in a range using a flow phantom. The measurements in a rat cerebral cortex show that the OCTA ...

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    2. Quantitative Assessment of Optical Coherence Tomography Angiography Algorithms for Neuroimaging

      Quantitative Assessment of Optical Coherence Tomography Angiography Algorithms for Neuroimaging

      Optical coherence tomography (OCT) angiography can noninvasively map microvascular networks and quantify blood flow in a cerebral cortex with a resolution of 1–10 μm and a penetration depth of 2–3 mm incorporating OCT signals and angiography algorithms. Different angiography algorithms have been developed in recent years; however, the performance of the algorithms has not been assessed quantitatively for neuroimaging applications. In this paper, we developed four metrics including vascular connectivity, contrast‐to‐noise ratio (CNR), signal‐to‐noise ratio (SNR) and processing time to quantitatively assess the performance of OCT angiography algorithms in image quality and computation speed ...

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      Mentions: Jiang Zhu
    1-2 of 2
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    1. (1 articles) Jiang Zhu
    2. (1 articles) Samsung
    3. (1 articles) Johns Hopkins University
    4. (1 articles) National Institutes of Health
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    6. (1 articles) University of São Paulo
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