1. Articles from Tino Just

    1-5 of 5
    1. Microanatomy of the tympanic membrane in chronic myringitis obtained with optical coherence tomography

      Microanatomy of the tympanic membrane in chronic myringitis obtained with optical coherence tomography

      A microscope-based optical coherence tomography (OCT) device was used to assess the microanatomy of the tympanic membrane in patients with chronic myringitis. A prospective study was designed for this purpose. OCT measurements of the tympanic membrane were done on 11 patients with myringitis with a microscope-based spectral domain OCT system. The in vivo findings were compared with those findings of a control group consisting of 36 patients with retraction pockets or atrophic tympanic membranes ( n = 13), myringosclerosis ( n = 12) and perforations ( n = 11). In active chronic myringitis, the thickness of the tympanic membrane is increased compared to healthy membranes and ...

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    2. Real-time volumetric optical coherence tomography OCT imaging with a surgical microscope

      Real-time volumetric optical coherence tomography OCT imaging with a surgical microscope
      Optical coherence tomography is a unique technique to visualize subsurface tissue structures with a resolution below 10μm during microsurgery without tissue contact. Since it was introduced more than 15 years ago imaging speed was boosted by more than three orders of magnitude, from less than 100 to more than 300,000 A-scans per second. Instead of taking only still images of anatomical structures, the increased speed of OCT allows now to image volumes nearly in real time. This enables not only the scanning of larger tissue surfaces, but also opens new application beyond simple diagnosis. A noncontact volumetric imaging with ...
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    3. An optical coherence tomography study for imaging the round window niche and the promontorium tympani

      An optical coherence tomography study for imaging the round window niche and the promontorium tympani
      Tympanosclerosis may involve the tympanic membrane, the ossicles, as well as the oval and round window niche, respectively. The surgical treatment of the obliterated oval window niche is most challenging. Beside stapesplasty, vibroplasty with coupling the floating mass transducer (FMT) onto the round window niche and into a new, so-called third window is indicated. In the latter situation, drilling a hole into the promontorium is necessary to couple the FMT close to the membranous endosteum. Any damage of the membranous inner ear needs to be avoided. The question was whether OCT is useful to identify the endosteum and to provide ...
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    4. Optical coherence tomography allows for the reliable identification of laryngeal epithelial dysplasia and for precise biopsy: A clinicopathological study of 61 patients undergoing microlaryngoscopy

      Optical coherence tomography allows for the reliable identification of laryngeal epithelial dysplasia and for precise biopsy: A clinicopathological study of 61 patients undergoing microlaryngoscopy
      Objectives/Hypothesis: A newly developed microscope-based spectral-domain optical coherence tomography (SD-OCT) device and an endoscope-based time-domain OCT (TD-OCT) were used to assess the inter-rater reliability, sensitivity, specificity, and accuracy of benign and dysplastic laryngeal epithelial lesions. Study Design: Prospective study. Methods: OCT during microlaryngoscopy was done on 35 patients with an endoscope-based TD-OCT, and on 26 patients by an SD-OCT system integrated into an operating microscope. Biopsies were taken from microscopically suspicious lesions allowing comparative study of OCT images and histology. Results: Thickness of the epithelium was seen to be the main criterion for degree of dysplasia. The inter-rater reliability ...
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    5. 3-D intraoperative imaging combining an operating microscope with optical coherence tomography (OCT)

      Objective Optical coherence tomography (OCT) allows non-contact/non-invasive analysis of tissues with a penetration depth of 2–3 mm reaching a spatial resolution of approximately 4–15 μm. This resolution is compatible with the resolution of modern operation microscopes. Aim of this work was to provide a three-dimensional (3D) intraoperative visualization of tissue structures. Material and methods A high-speed spectral domain OCT (a modified version of the Ganymed, Thorlabs HL) was adapted to a motorized operation microscope (HR 1000, Möller-Wedel). Via a specially designed two axis-scanner, the 840 nm OCT was adapted directly to a camera port of the operation ...
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    1-5 of 5
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