1. Articles from Paulo Lizano

    1-4 of 4
    1. Retinal microvasculature and vasoreactivity changes in hypertension using optical coherence tomography-angiography

      Retinal microvasculature and vasoreactivity changes in hypertension using optical coherence tomography-angiography

      Purpose: To evaluate the retinal vasculature and vasoreactivity of patients with hypertension (HTN) using spectral domain optical coherence tomography angiography (SD-OCTA). Methods: Patients with and without a diagnosis of HTN were included in this cross-sectional observational study. All eyes were imaged with SD-OCTA using 3 mm × 3 mm and 6 mm × 6 mm centered on both the fovea and optic disk. A second 6 mm × 6 mm scan was taken after a 30 s breath-hold. Vessel density (VD), vessel skeletonized density (VSD), and fractal dimension (FD) were calculated using customized MATLAB scripts. Vessel diameter index (VDI) was obtained by taking ...

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    2. Quantifying Retinal Microvascular Morphology in Schizophrenia Using Swept-Source Optical Coherence Tomography Angiography

      Quantifying Retinal Microvascular Morphology in Schizophrenia Using Swept-Source Optical Coherence Tomography Angiography

      Background: Retinovascular changes are reported on fundus imaging in schizophrenia (SZ). This is the first study to use swept-source optical coherence tomography angiography (OCT-A) to comprehensively examine retinal microvascular changes in SZ. Methods: This study included 30 patients with SZ/schizoaffective disorder (8 early and 15 chronic) and 22 healthy controls (HCs). All assessments were performed at Beth Israel Deaconess Medical Center and Massachusetts Eye and Ear. All participants underwent swept-source OCT-A of right (oculus dextrus [OD]) and left (oculus sinister [OS]) eye, clinical, and cognitive assessments. Macular OCT-A images (6 × 6 mm) were collected with the DRI Topcon Triton ...

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    3. Inter-device reliability of swept source and spectral domain optical coherence tomography and retinal layer differences in schizophrenia

      Inter-device reliability of swept source and spectral domain optical coherence tomography and retinal layer differences in schizophrenia

      Introduction Optical coherence tomography (OCT) is used to study retinal structure in schizophrenia. Changes in retinal structure, especially the retinal nerve fiber layer (RNFL) has been correlated with psychotic disorders. Measurement variability is a concern since there are various generations of OCT devices. We investigated the inter- and intra-device agreement of macular thickness between spectral domain (SD−OCT) and swept source−OCT (SS−OCT), and compared macula and peripapillary group differences in schizophrenia using SS−OCT. Methods Macular OCT thickness was obtained for schizophrenia (SZ, n = 30) and healthy controls (HC, n = 22) subjects using SD−OCT (Heidelberg Spectralis) and ...

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    4. Superficial Retinal Vascular Abnormalities in Schizophrenia as Shown by Swept Source OCT-Angiography: A Preliminary Study

      Superficial Retinal Vascular Abnormalities in Schizophrenia as Shown by Swept Source OCT-Angiography: A Preliminary Study

      Altered microvasculature is central to the pathophysiology of many CNS disorders, but it has received less attention in schizophrenia. Since retinal and cerebral microvessels are homologous in structure/function, the retina can be used as a window into the brain. Studies using fundus imaging in schizophrenia have identified decreased arteriole diameter and tortuosity, as well as increased venule diameter and tortuosity. Herein, we explore the ability of optical coherence tomography angiography (OCTA) to identify fine retinal vessel alterations in schizophrenia.

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    1-4 of 4
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  2. Topics in the News

    1. (2 articles) Massachusetts Eye and Ear Infirmary
    2. (2 articles) Beth Israel Deaconess Medical Center
    3. (2 articles) Harvard University
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    Superficial Retinal Vascular Abnormalities in Schizophrenia as Shown by Swept Source OCT-Angiography: A Preliminary Study Inter-device reliability of swept source and spectral domain optical coherence tomography and retinal layer differences in schizophrenia Quantifying Retinal Microvascular Morphology in Schizophrenia Using Swept-Source Optical Coherence Tomography Angiography Retinal microvasculature and vasoreactivity changes in hypertension using optical coherence tomography-angiography Postdoctoral Fellows/Research Scientists at University of Washington, Seattle Perimeter Medical Imaging AI Announces Publication of Peer-Reviewed Journal Article Validating Potential Use of Wide-Field Optical Coherence Tomography (WF-OCT) in Head and Neck Surgeries Association of retinal thickness and microvasculature with cognitive performance and brain volumes in elderly adults A Deep Learning Framework for the Detection and Quantification of Reticular Pseudodrusen and Drusen on Optical Coherence Tomography Quantitative assessment of textural features in the early detection of diabetic retinopathy with optical coherence tomography angiography Line-field confocal optical coherence tomography of fibroepithelioma of Pinkus Assessment of demineralized tooth lesions using optical coherence tomography and other state-of-the-art technologies: a review Optic disc and retinal vessel densities assessment by optical coherence tomography angiography in patients with keratoconus