1. Articles from nicusor v. iftimia

    1-12 of 12
    1. Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue

      Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue

      A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path.

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    2. Combined Reflectance Confocal Microscopy-Optical Coherence Tomography System for Imaging of Biological Tissue

      Combined Reflectance Confocal Microscopy-Optical Coherence Tomography System for Imaging of Biological Tissue

      A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path.

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    3. Multi-functional adaptive optics retinal imaging

      Multi-functional adaptive optics retinal imaging

      An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second ...

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    4. Adaptive optics line scanning ophthalmoscope

      Adaptive optics line scanning ophthalmoscope

      A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the portion of the eye.

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    5. Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope

      Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope
      An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser ophthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of ...
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    6. System and method for identifying tissue using low-coherence interferometry

      System and method for identifying tissue using low-coherence interferometry
      An apparatus for needle biopsy with real time tissue differentiation using one dimensional interferometric ranging imaging, comprising a biopsy device having a barrel and a needle, an optical fiber inserted in the needle, and a fiber optic imaging system connected to the optical fiber. The imaging system obtains images and compares the optical properties and patterns to a database of normalized tissue sample images to determine different tissue types. The physician performing the biopsy obtains feedback via a feedback unit associated with the biopsy device and which is connected to the imaging system. The feedback unit can provide visual, audible ...
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    7. Stabilized retinal imaging with adaptive optics

      Stabilized retinal imaging with adaptive optics
      A system provides an optical image of an object. A first module tracks a reference feature of the object. A second module includes a source for an imaging beam, a scanning device to move the imaging beam along a portion of the object and a detection device receives a signal associated with an image of the portion of the object. The first module controls the position of the imaging beam relative to the reference feature to correct for the motion of the object. A third module detects a distortion of the object and compensates for the distortion.
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    8. Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope

      Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope
      An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser ophthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of ...
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    9. Swept-source parallel OCT

      We present an optical coherence tomography (OCT) system that can create a full 2D cross-sectional image of a sample within one single spectral sweep of a swept source at a frame rate of 160 fps. The unique combination of line field and swept source technologies in a Fourier domain OCT configuration achieves ultrahigh imaging speeds with a greatly simplified wavelength swept source. The system was initially tested on reflective and diffuse targets.

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    10. Real-time processing for Fourier domain optical coherence tomography using a field programmable gate array

      Teoman E. Ustun, Nicusor V. Iftimia, R. Daniel Ferguson, and Daniel X. Hammer Real-time display of processed Fourier domain optical coherence tomography (FDOCT) images is important for applications that require instant feedback of image information, for example, systems developed for rapid screening or image-guided surgery. However, the computational requirements for high-spe ... [Rev. Sci. Instrum. 79, 114301 (2008)] published Mon Nov 3, 2008.
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    11. Dual-beam Fourier domain optical Doppler tomography of zebrafish

      Dual-beam Fourier domain optical Doppler tomography of zebrafish

      We have developed a dual-beam Fourier domain optical Doppler tomography (FD-ODT) system to image zebrafish (Danio rerio) larvae. Two beams incident on the zebrafish with a fixed angular separation allow absolute blood flow velocity measurement to be made regardless of vessel orientation in a ... [Opt. Express 16, 13624-13636 (2008)]

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    12. Foveal Fine Structure in Retinopathy of Prematurity: An Adaptive Optics Fourier Domain Optical Coherence Tomography Study

      purpose. To describe the fine structure of the fovea in subjects with a history of mild retinopathy of prematurity (ROP) using adaptive optics–Fourier domain optical coherence tomography (AO-FDOCT). methods. High-speed, high-resolution AO-FDOCT videos were recorded in subjects with a history of ROP (n = 5; age range, 14–26 years) and in control subjects (n = 5; age range, 18–25 years). Custom software was used to extract foveal pit depth and volume from three-dimensional (3-D) retinal maps. The thickness of retinal layers as a function of retinal eccentricity was measured manually. The retinal vasculature in the parafoveal region was assessed ...
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    1-12 of 12
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    1. (11 articles) R. Daniel Ferguson
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    Dual-beam Fourier domain optical Doppler tomography of zebrafish Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope System and method for identifying tissue using low-coherence interferometry Stabilized retinal imaging with adaptive optics Hybrid spectral domain optical coherence tomography line scanning laser ophthalmoscope Adaptive optics line scanning ophthalmoscope Multi-functional adaptive optics retinal imaging In vivo dynamic characterization of the human tympanic membrane using pneumatic optical coherence tomography Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography Spectral Domain – Optical Coherence Tomography findings in Triple-A Syndrome – A case series from Pakistan Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty A preliminary study of post-progressive nail-art effects on in vivo nail plate using optical coherence tomography-based intensity profiling assessment