-
Popular Articles
Differential permeability rate and percent clearing of glucose in different regions in rabbit sclera
The effect of solution concentration on diffusion in scleral tissues
Enhanced OCT imaging of embryonic tissue with optical clearing
Concentration effect on the diffusion of glucose in ocular tissues
Permeability of hyperosmotic agent in normal and atherosclerotic vascular tissues
Quantification of microbubbles in blood with phase-sensitive SSOCT
-
Quantification of microbubbles in blood with phase-sensitive SSOCT
Explore Article SPIE Digital Library (Feb 23 2010)
We have developed a phase stabilized swept source optical coherence tomography (PhS-SSOCT), that shows an axial resolution of 10 µm, phase sensitivity of 0.04 radians, imaging depth of up to 6 mm in air and a scanning speed of 20 kHz for a single A-line. In this paper, the PhS-SSOCT is applied to quantify gas microbubbles in blood in vitro. The results indicate that the system is able to detect bubbles of diameters greater than 10 µm using the structural image and the microbubbles of diameter less than 10 µm could be detected using the temporal phase response. Images of ...
(Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston
-
Enhanced OCT imaging of embryonic tissue with optical clearing
Explore Article SPIE Digital Library (Feb 20 2009)
Optical coherence tomography (OCT) holds great promise as a routine research tool for 3-D analysis of mammalian embryos. However, despite the depth penetration afforded by this imaging modality, light attenuation in tissues imposes limitations. Here we studied the optical clearing effect of differen ... [Proc. SPIE 7168, 71682C (2009)] published Fri Feb 20, 2009. (Read Full Article)
Comment on Article Mentions: Valery V. Tuchin Baylor College of Medicine Kirill V. Larin
-
Concentration effect on the diffusion of glucose in ocular tissues
Explore Article ScienceDirect (Jun 17 2008)
In this study, optical coherence tomography (OCT) was utilized in the functional imaging of glucose diffusion through scleral tissues. Permeability coefficients for different concentrations of glucose were quantified nondestructively. Obtained results indicate an inverse proportionality between the permeability coefficient and the concentration of the analyte in epithelial tissues: in-depth diffusion of solutions with lower glucose concentration was faster than those with a higher concentration. The permeability coefficient decreased from (1.67±0.17)×10−5 cm/s of 10% glucose solution to (5.08±0.23)×10−6 cm/s of 25% glucose solution. The dependence of the permeability on the concentration of hyperosmotic analytes could potentially be used in various basic ... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston Saratov State University
-
The effect of solution concentration on diffusion in scleral tissues
Explore Article SPIE Digital Library (Jun 9 2008) Glucose , Ophthalmology
Mohamad G. Ghosn, Esteban F. Carbajal, Natasha A. Befrui et al. The calculation of permeability coefficient of analytes could potentially be used in a variety of basic science and clinical fields, as well as advanced diagnostic imaging. Before this can occur, a more thorough understanding of the diffusion rate of analytes in biological tissues is needed. For thi ... [Proc. SPIE 6791, 679107 (2008)] published Mon Jun 9, 2008. (Read Full Article)
Comment on Article Mentions: Mohamad G. Ghosn Kirill V. Larin University of Houston
-
Differential permeability rate and percent clearing of glucose in different regions in rabbit sclera
Explore Article SPIE Digital Library (Apr 21 2008) Glucose , Ophthalmology
Mohamad G. Ghosn, Esteban F. Carbajal, Natasha A. Befrui et al. Imaging of biological tissues with optical coherence tomography (OCT) poses a great interest for its capability to noninvasively outline subsurface microstructures within tissues. However, a major limitation for many optical imaging techniques is inadequate depth penetration of light in turbid media ... [J. Biomed. Opt. 13, 021110 (2008)] published Mon Apr 21, 2008. (Read Full Article)
Comment on Article Mentions: Saratov State University Mohamad G. Ghosn University of Houston
-
Permeability of hyperosmotic agent in normal and atherosclerotic vascular tissues
Explore Article SPIE Digital Library (Feb 28 2008) Cardiology
Noninvasive cardiovascular imaging could lead to the early detection and timely treatment of complex atherosclerotic lesions responsible for major cardiovascular events. Recent investigations have suggested that optical coherence tomography (OCT) is an ideal diagnostic tool due to the high resolution this technology achieves in discriminating the different features of atherosclerotic lesions based on structural imaging. We explore the capability of OCT for functional imaging of normal and atherosclerotic aortic tissues based on time- and depth-resolved quantification of the permeability of biomolecules through these tissues. The permeability coefficient of 20% aqueous solution of glucose was found to be (6.80±0.18)×10−6 cm/s in ... (Read Full Article)
Comment on Article Mentions: Kirill V. Larin University of Houston Mohamad G. Ghosn







Recent Comments
Eric Swanson » Jim Fujimoto video: Biophotonics and optical coherence tomography
Great video Jim!
dariemihaela » Gary S. Mintz
Dear Prof. Dr. Gary S. Mintz, You are an extraordinary expert in imaging, an intelligence ...
See all recent comments