1. Articles from Nadia Waheed

    1-10 of 10
    1. ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY

      ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY

      Purpose: To determine which spectral domain optical coherence tomography biomarkers of idiopathic macular hole (MH) correlate with the postoperative best-corrected visual acuity (BCVA) in anatomically closed MH. Methods: Retrospective analysis of spectral domain optical coherence tomography scans of 44 patients presenting with MH followed for a mean of 17 months. Widths of MH aperture, base, and ellipsoid zone disruption were calculated from presenting foveal spectral domain optical coherence tomography B-scans. Macular hole base area and ellipsoid zone disruption area were calculated through the custom in-house software. Results: Poorer postoperative BCVA correlated with increased preoperative choroidal hypertransmission (r = 0.503, P ...

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    2. Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography

      Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography

      Purpose : To analyze the evolution of type 1 neovascularization associated with vascularized serous pigment epithelial detachment (vsPED) using three-dimensional, volumetric, en face optical coherence tomography angiography (OCTA). Methods : This was a retrospective case series from four tertiary medical centers. OCTA images were analyzed at baseline and at the 3-, 6-, 12-, 18-, and 24-month follow-up visit when available. Visual acuity, number of injections, PED maximal height and PED area and volume, and choroidal neovascularization (CNV) flow area and progression were determined at each visit. Qualitative and quantitative analysis of CNV progression (including CNV/PED flow area) and final PED morphology ...

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    3. Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series

      Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series

      Objective To compare clinical characteristics of patients suffering from neovascular age-related macular degeneration (nAMD) with mature and immature choroidal neovascularisation (CNV) as assessed by optical coherence tomography angiography (OCTA). To explore the effect of total anti-vascular endothelial growth factor exposure on the occurrence of mature CNV when correcting for potential confounders. Methods and analysis In this retrospective case series, we included 40 eyes of 36 patients with nAMD with CNV assessed by OCTA at the Manchester Eye Hospital between June 2016 and June 2017. A retinal specialist masked to patient information graded CNV depicted on OCTA scans. For statistical comparisons ...

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    4. COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study)

      COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study)

      Importance The relationship between peripheral retinal capillary non-perfusion with central NP is non-linear. Objective To systematically examine the relationships between the microvascular indices that are measured on OCTA and the presence and extent of peripheral non-perfusion in persons with diabetic retinopathy Design Retrospective cross-sectional study of patients with varying degrees of diabetic retinopathy ; Setting: Two large tertiary referral retina clinics Participants Eighty-two eyes of forty-five patients with varying degrees of diabetic retinopathy were enrolled and analyzed Main outcome Relationships between peripheral ischemia measured on FA and OCTA metrics, including FAZ and vessel density measurements. Results A significant decrease in mean ...

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    5. Atlas of Retinal OCT: Optical Coherence Tomography (Textbook)

      Atlas of Retinal OCT: Optical Coherence Tomography (Textbook)

      Optical Coherence Tomography has revolutionized today’s eye care. This remarkable non-invasive scanning technology is unparalleled for aiding diagnosis of retinal disease and recording disease progression. Atlas of Retinal OCT: Optical Coherence Tomography provides expert guidance in this rapidly evolving area with high-quality, oversized images that show precise detail and assist with rapid, accurate clinical decision making.

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    6. Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second

      Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second

      Purpose: To develop and demonstrate a cardiac gating method for repeatable in vivo measurement of total retinal blood flow (TRBF) in humans using en face Doppler optical coherence tomography (OCT) at commercially available imaging speeds. Methods: A prototype swept-source OCT system operating at 100 kHz axial scan rate was developed and interfaced with a pulse oximeter. Using the plethysmogram measured from the earlobe, Doppler OCT imaging of a 1.5 mm×2 mm area at the optic disc at 1.8 volumes/sec was synchronized to cardiac cycle to improve sampling of pulsatile blood flow. Post-processing algorithms were developed to ...

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    7. Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath

      We characterized en face features of the retinal pigment epithelium (RPE) and choroid in eyes with chronic central serous chorioretinopathy (CSCR) using a high-speed, enhanced tissue penetration, swept-source optical coherence tomography (SS-OCT) prototype. Fifteen eyes of 13 consecutive patients with the clinical diagnosis of CSCR were prospectively examined with SS-OCT. Three-dimensional 6x6mm macular cube raster scans were obtained with SS-OCT operating at 1050nm wavelength and 100,000 A-lines/sec with 6µm axial resolution. Segmentation of the RPE generated a reference surface; en face SS-OCT images of the RPE and choroid were extracted at varying depths every 3.5 µm ...

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    8. En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy

      En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy

      Objective To characterize en face features of the retinal pigment epithelium (RPE) and choroid in eyes with chronic central serous chorioretinopathy (CSCR) using a high-speed, enhanced-depth swept-source optical coherence tomography (SS-OCT) prototype. Design Consecutive patients with chronic CSCR were prospectively examined with SS-OCT. Participants Fifteen eyes of 13 patients. Methods Three-dimensional 6×6 mm macular cube raster scans were obtained with SS-OCT operating at 1050 nm wavelength and 100 000 A-lines/sec with 6 μm axial resolution. Segmentation of the RPE generated a reference surface; en face SS-OCT images of the RPE and choroid were extracted at varying depths every ...

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    9. Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography

      Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography

      Purpose: The purpose of this study was to characterize diabetic retinal neovascularization (NV) and accompanying retinal and vitreal morphologic changes using high-resolution spectral domain optical coherence tomography. Methods: A cross-sectional retrospective analysis was performed on 16 eyes of 14 nonconsecutive subjects with proliferative diabetic retinopathy that were seen between August 2011 and December 2011 at the New England Eye Center, Boston, MA. Patients who had NV of the disk, NV elsewhere, and intraretinal microvascular abnormalities were scanned using optical coherence tomography directly over the region of the abnormal vessels. Results: Characteristic changes of the retinal vasculature, retina, and vitreous were ...

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    10. Comparing Retinal Thickness Measurements Using Automated Fast Macular Thickness Map versus Six-Radial Line Scans with Manual Measurements

      Purpose: To compare automated retinal thickness values generated by the fast macular thickness maps (FMTM) and customized 6-radial line scans (RLS) versus manual retinal measurements on Stratus optical coherence tomography (OCT) (Carl Zeiss Meditec, Dublin, CA). Design: Prospective, observational case series. Participants: Patients with subfoveal choroidal neovascularization (CNV) caused by age-related macular degeneration (AMD), diabetic macular edema (DME), or branch/central retinal vein occlusion (RVO). Methods: Patients were prospectively imaged using the FMTM and customized RLS patterns on Stratus OCT at the same sitting. Each scan was evaluated for errors in retinal segmentation (i.e., correct retinal boundaries [CRB]). Automated ...

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    1-10 of 10
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    1. (10 articles) Nadia K. Waheed
    2. (9 articles) Tufts University
    3. (5 articles) Jay S. Duker
    4. (3 articles) Massachusetts Institute of Technology
    5. (3 articles) Jonathan J. Liu
    6. (3 articles) James G. Fujimoto
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    Retinal Neovascularization Secondary to Proliferative Diabetic Retinopathy Characterized By Spectral Domain Optical Coherence Tomography En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopathy Feature Of The Week 2/16/14: En Face Enhanced-Depth Swept-Source Optical Coherence Tomography Features of Chronic Central Serous Chorioretinopath Cardiac-Gated En Face Doppler Measurement of Retinal Blood Flow Using Swept Source Optical Coherence Tomography at 100,000 Axial Scans per Second Atlas of Retinal OCT: Optical Coherence Tomography (Textbook) COmbined multimodal analysis of Peripheral Retinal and mAcular circulation in Diabetic Retinopathy (COPRA Study) Effect of total anti-VEGF treatment exposure on patterns of choroidal neovascularisation assessed by optical coherence tomography angiography in age-related macular degeneration: a retrospective case series Volumetric Analysis of Vascularized Serous Pigment Epithelial Detachment Progression in Neovascular Age-Related Macular Degeneration Using Optical Coherence Tomography Angiography ASSESSING THE ABILITY OF PREOPERATIVE QUANTITATIVE SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS TO PREDICT VISUAL OUTCOME IN IDIOPATHIC MACULAR HOLE SURGERY Spectral Domain Optical Coherence Tomography Imaging Performance Improvement Based on Field Curvature Aberration-Corrected Spectrometer Pentosan polysulfate maculopathy versus inherited macular dystrophies: comparative assessment with multimodal imaging Complementary Use of Active Infrared Thermography and Optical Coherent Tomography in Non-destructive Testing Inspection of Ancient Marquetries