1. Articles from Aiko Hara

    1-2 of 2
    1. The qualitative assessment of optical coherence tomography and the central retinal sensitivity in patients with retinitis pigmentosa

      The qualitative assessment of optical coherence tomography and the central retinal sensitivity in patients with retinitis pigmentosa

      Purpose To analyze the relationships between qualitative and quantitative parameters of spectral-domain optical coherence tomography (SD-OCT) and the central retinal sensitivity in patients with retinitis pigmentosa (RP). Materials and methods Ninety-three eyes of 93 patients were finally enrolled, with a median age (quartile) of 58 (24.5) years. We assessed the patients using SD-OCT and the 10–2 program of a Humphry Field Analyzer (HFA). As a qualitative parameter, two graders independently classified the patients’ SD-OCT images into five severity grades (grades 1–5) based on the severity of damage to the photoreceptor inner and outer segments (IS/OS) layer ...

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    2. Optical Coherence Tomography of Animal Models of Retinitis Pigmentosa: From Animal Studies to Clinical Applications

      Optical Coherence Tomography of Animal Models of Retinitis Pigmentosa: From Animal Studies to Clinical Applications

      Purpose . The aim of this study was to understand the relationship between the findings of spectral-domain optical coherence tomography (SD-OCT) of previously reported animal models of retinitis pigmentosa (RP) associated with known genetic mutations and their background structural and functional changes. Methods . We reviewed previous publications reporting the SD-OCT findings of animal models of RP and summarized the characteristic findings of SD-OCT in nine different animal models ( RCS –/– , RHO P23H, RHO S334ter, RHO –/– , Rpe65 –/– , rp12, Pde6β –/– (rd1 and rd10), and Arr1 –/– ) of human RP. Results . Despite the various abnormal structural changes found in these different animal models, progressive thinning of ...

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    1-2 of 2
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  2. Topics in the News

    1. (1 articles) University of Florida
    2. (1 articles) Tohoku University
    3. (1 articles) Carl Zeiss Meditec
    4. (1 articles) Alcon
    5. (1 articles) Haag-Streit
    6. (1 articles) Wakayama Medical University
    7. (1 articles) Takashi Kubo
    8. (1 articles) Takashi Akasaka
    9. (1 articles) Yasushi Ino
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