1. Articles from Katharina Blessing

    1-5 of 5
    1. Depth encoded input polarisation independent swept source cross-polarised optical coherence tomography probe

      Depth encoded input polarisation independent swept source cross-polarised optical coherence tomography probe

      Within the last decades, several studies have been published that prove the benefit of polarisation sensitive optical coherence (psOCT) tomography for the field of biomedical diagnostics. However, polarisation sensitive imaging typically requires careful control of the polarisation state of the input illumination, which leads to bulky and delicate systems. While psOCT provides quantitative information, it is mostly sufficient to analyse the images qualitatively in the field of biomedical diagnostics. Therefore, a reduced form of this technique, cross-polarised optical coherence tomography (cpOCT), moves into the focus of interest that serves to visualise the birefringence properties of a sample. Despite the low ...

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    2. Novel input polarisation independent endoscopic cross polarised optical coherence tomography probe

      Novel input polarisation independent endoscopic cross polarised optical coherence tomography probe

      Lead by the original idea to perform noninvasive optical biopsies of various tissue, optical coherence tomography found numerous medical applications within the last two decades. The interference based imaging technique opens the possibility to visualise subcellular morphology up to an imaging depth of 3 mm and up to micron level axial and lateral resolution. The birefringence properties of the tissue are visualised with enhanced contrast using polarisation sensitive or cross polarised optical coherence tomography techniques. Although, it requires strict control over the polarisation states, resulting in several polarisation controlling elements. In this work, we propose a novel inputā€polarisaion independent ...

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    3. Input polarization-independent polarization-sensitive optical coherence tomography using a depolarizer

      Input polarization-independent polarization-sensitive optical coherence tomography using a depolarizer

      Polarization-sensitive optical coherence tomography is gaining attention because of its ability to diagnose certain pathological conditions at an early stage. The majority of polarization-sensitive optical coherence tomography systems require a polarization controller and a polarizer to obtain the optimal polarization state of the light at the sample. Such systems are prone to misalignment since any movement of the optical fiber normally coupled to the light source will change the polarization state of the incident beam. We propose and demonstrate an input polarization-independent polarization-sensitive optical coherence tomography system using a depolarizer that works for any input polarization state of the light ...

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    4. Swept source cross-polarized optical coherence tomography for any input polarized light

      Swept source cross-polarized optical coherence tomography for any input polarized light

      Cross polarized optical coherence tomography offers enhanced contrast in certain pathological conditions. Traditional cross-polarized optical coherence tomography systems require a defined input polarization and thus require several polarization controlling elements increasing the overall complexity of the system. Our proposed system requires a single quarter wave plate as a polarization controller thus simplifying the system significantly. Majority of Cross-polarized optical coherence tomography systems are spectrometer based which suffers from slow speed and low signal to noise ratio. In this work, we present a swept source based cross-polarized optical coherence tomography system that works for any input polarization state. The system was ...

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    5. Low cost scalable monolithic common path probe design for the application in endoscopic optical coherence tomography

      Low cost scalable monolithic common path probe design for the application in endoscopic optical coherence tomography

      Endoscopic optical coherence tomography is an interference based imaging technique which due to its micron level resolution ability found several applications in medical diagnostics. However, the standard image performance suffers from artefacts caused by dispersion imbalance and polarisation mismatches between reference and sample arm. Such artefacts can be minimised with the use of a special class of probes called common path probes where the reference surface is placed in the vicinity of the sample. Previously reported common path probes suffered from a compromise between sensitivity and resolution. In most cases, proposed probes were not scalable for industrial applications and required ...

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    1-5 of 5
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    Low cost scalable monolithic common path probe design for the application in endoscopic optical coherence tomography Swept source cross-polarized optical coherence tomography for any input polarized light Input polarization-independent polarization-sensitive optical coherence tomography using a depolarizer Novel input polarisation independent endoscopic cross polarised optical coherence tomography probe Depth encoded input polarisation independent swept source cross-polarised optical coherence tomography probe Post-Doctoral and Graduate Student Research Positions at the University of Illinois Urbana-Champaign Multiscale correlation of microvascular changes on optical coherence tomography angiography with retinal sensitivity in diabetic retinopathy Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque PERSONALIZED CHARACTERISTICS OF MORPHOMETRIC AND FUNCTIONAL PARAMETERS OF RETINA IN ARTERIAL HYPERTENTION ACCORDING TO OPTICAL COHERENCE TOMOGRAPHY-ANGIOGRAPHY DATA Coherence function-encoded optical palpation Systems, methods, and media for multiple reference arm spectral domain optical coherence tomography Monitoring dissolution of a dosage form in progress during dissolution by low coherence interferometry