1. Articles from Marina Sirotkina

    1-3 of 3
    1. Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use

      Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use

      This work is dedicated to the development of the OCT system with angiography for everyday clinical use. Two major problems were solved during the development: compensation of specific natural tissue displacements, induced by contact scanning mode and physiological motion of patients (eg, respiratory and cardiac motions) and online visualization of vessel cross‐sections to provide feedback for the system operator.

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    2. Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography

      Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography

      A novel machine-learning method to distinguish between tumor and normal tissue in optical coherence tomography (OCT) has been developed. Pre-clinical murine ear model implanted with mouse colon carcinoma CT-26 was used. Structural-image-based feature sets were defined for each pixel and machine learning classifiers were trained using “ground truth” OCT images manually segmented by comparison with histology. The accuracy of the OCT tumour segmentation method was then quantified by comparing with fluorescence imaging of tumors expressing genetically encoded fluorescent protein KillerRed that clearly delineates tumor borders. Since the resultant 3D tumor/normal structural maps are inherently co-registered with OCT derived maps ...

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    3. Contrasting properties of gold nanoshells and titanium dioxide nanoparticles for optical coherence tomography imaging of skin: Monte Carlo simulations and in vivo study

      Contrasting properties of gold nanoshells and titanium dioxide nanoparticles for optical coherence tomography imaging of skin: Monte Carlo simulations and in vivo study
      The effect of silica/gold nanoshells and titanium dioxide nanoparticles on the optical properties of skin is studied. By implementing in vivo measurements and Monte Carlo simulations, we analyze the efficiency of using these nanoparticles as contrasting agents for optical coherence tomography (OCT) imaging of skin. In vivo measurements are performed on pig skin, where nanoparticle suspension drops have been applied. The identification of skin layers is performed by comparison with corresponding histology images. Experimental results exhibit an increase in contrast of the obtained OCT images after a single nanoparticles application. Multiple applications do not lead to increase in the ...
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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Institute of Applied Physics
    2. (3 articles) Nizhny Novgorod State Medical Academy
    3. (3 articles) Elena V. Zagaynova
    4. (2 articles) University of Toronto
    5. (2 articles) Grigory V. Gelikonov
    6. (2 articles) Natalia D. Gladkova
    7. (2 articles) Valentin M. Gelikonov
    8. (2 articles) Elena B. Kiseleva
    9. (2 articles) I. Alex Vitkin
    10. (1 articles) Mikhail Y. Kirillin
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    Contrasting properties of gold nanoshells and titanium dioxide nanoparticles for optical coherence tomography imaging of skin: Monte Carlo simulations and in vivo study Pixel classification method in optical coherence tomography for tumor segmentation and its complementary usage with OCT microangiography Optical coherence tomography‐based angiography device with real‐time angiography B‐scans visualization and hand‐held probe for everyday clinical use An air of optimism takes hold for CF sufferers Optical coherence tomography for dynamic axial correction of an optical end-effector for robot-guided surgical laser ablation Optical Coherence Tomography Angiography to Assess Vascular Remodeling of the Choriocapillaris After Low-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy Automatic Classification of Retinal Optical Coherence Tomography Images With Layer Guided Convolutional Neural Network Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity Segmentation of Retinal Cysts From Optical Coherence Tomography Volumes Via Selective Enhancement OCT Signs Associated With Fellow Eye AMD Progression Convective Nozaki-Bekki holes in a long cavity OCT laser Research Associate in Biophotonics Openings at the Univesity of Sheffield (2 openings)