1. Articles from Rowan W. Sanderson

    1-4 of 4
    1. Feature Of The Week 04.26.2020: Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Feature Of The Week 04.26.2020: Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Inadequate margins in breast-conserving surgery (BCS) are associated with an increased likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS patients require repeat surgery due to inadequate margins at the initial operation. Implementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate. This study determined, for the first time, the diagnostic accuracy of quantitative micro-elastography (QME), an optical coherence tomography (OCT)–based elastography technique that produces images of tissue microscale elasticity, for detecting tumor within 1 mm of the margins of BCS specimens. Simultaneous OCT and QME were performed on the margins of intact ...

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    2. Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery

      Inadequate margins in breast-conserving surgery (BCS) are associated with an increased likelihood of local recurrence of breast cancer. Currently, approximately 20% of BCS patients require repeat surgery due to inadequate margins at the initial operation. Implementation of an accurate, intraoperative margin assessment tool may reduce this re-excision rate. This study determined, for the first time, the diagnostic accuracy of quantitative micro-elastography (QME), an optical coherence tomography (OCT)–based elastography technique that produces images of tissue microscale elasticity, for detecting tumor within 1 mm of the margins of BCS specimens. Simultaneous OCT and QME were performed on the margins of intact ...

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    3. Handheld volumetric manual compression‐based quantitative micro‐elastography

      Handheld volumetric manual compression‐based quantitative micro‐elastography

      Compression optical coherence elastography typically requires a mechanical actuator to impart a controlled uniform strain to the sample. However, for handheld scanning, this adds complexity to the design of the probe and the actuator stroke limits the amount of strain that can be applied. In this work, we present a new volumetric imaging approach that utilises bidirectional manual compression via the natural motion of the user's hand to induce strain to the sample, realising compact, actuator‐free, handheld compression optical coherence elastography. In this way, we are able to demonstrate rapid acquisition of three‐dimensional quantitative micro‐elastography (QME ...

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    4. Finger-mounted quantitative micro-elastography

      Finger-mounted quantitative micro-elastography

      We present a finger-mounted quantitative micro-elastography (QME) probe, capable of measuring the elasticity of biological tissue in a format that avails of the dexterity of the human finger. Finger-mounted QME represents the first demonstration of a wearable elastography probe. The approach realizes optical coherence tomography-based elastography by focusing the optical beam into the sample via a single-mode fiber that is fused to a length of graded-index fiber. The fiber is rigidly affixed to a 3D-printed thimble that is mounted on the finger. Analogous to manual palpation, the probe compresses the tissue through the force exerted by the finger. The resulting ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Western Australia
    2. (4 articles) Brendan F. Kennedy
    3. (3 articles) Andrea Curatolo
    4. (2 articles) Ruchire Eranga Wijesinghe
    5. (2 articles) Kelsey M. Kennedy
    6. (2 articles) OncoRes Medical
    7. (2 articles) Medical University of Vienna
    8. (1 articles) University of St. Andrews
    9. (1 articles) Nara Medical University
    10. (1 articles) K. U. Leuven
    11. (1 articles) University of Alabama
    12. (1 articles) Singapore Eye Research Institute
    13. (1 articles) Michael Pircher
    14. (1 articles) Taishi Yonetsu
    15. (1 articles) Ursula Schmidt-Erfurth
    16. (1 articles) Tsunekazu Kakuta
    17. (1 articles) Dalip Singh Mehta
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    Finger-mounted quantitative micro-elastography Handheld volumetric manual compression‐based quantitative micro‐elastography Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery Feature Of The Week 04.26.2020: Diagnostic Accuracy of Quantitative Micro-Elastography for Margin Assessment in Breast-Conserving Surgery High space-bandwidth in quantitative phase imaging using partially spatially coherent optical coherence microscopy and deep neural network Optical coherence tomography assessment of macrophages accumulation in non-ST-segment elevation acute coronary syndromes Early disability in ambulatory patients with multiple sclerosis: optical coherence tomography versus visual evoked potentials, a comparative study Dueling Deep Q-Network for Unsupervised Inter-frame Eye Movement Correction in Optical Coherence Tomography Volumes Atlas of Optical Coherence Tomography for Glaucoma (Textbook) In-vivo analysis of iron-gold composite nanoparticles as potential exogenous contrast agents for Magnetomotive Optical Coherence Tomography (MMOCT) Automatic Classification of Volumetric Optical Coherence Tomography Images via Recurrent Neural Network Noise-Powered Disentangled Representation for Unsupervised Speckle Reduction of Optical Coherence Tomography Images