1. Articles from Joanna J. Wykrzykowska

    1-16 of 16

    1. Differences in rotational positioning and subsequent distal main branch rewiring of the Tryton stent: An optical coherence tomography and computational study

      Explore Wiley Online Library Cardiology
      Differences in rotational positioning and subsequent distal main branch rewiring of the Tryton stent: An optical coherence tomography and computational study

      Objectives To evaluate the occurrence of rewiring through one of the panels of the Tryton stent (instead of the assumed re-wiring in-between the panels) and the influence on stent geometry and mechanics. Background Tryton is a side branch stent used in combination with a main branch device. It is placed without the need of rotational orientation. However, it is unknown whether main branch re-wiring accidentally may occur through a panel, instead of in-between the panels. Methods We used three-dimensional optical coherence tomography to evaluate the location of distal main branch re-wiring through Tryton. Furthermore, we used computer simulations to evaluate ...

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    2. Scaffold thrombosis following implantation of the Absorb Bvs in routine clinical practice: Insight into possible mechanisms from optical coherence tomography

      Explore Wiley Online Library Cardiology
      Scaffold thrombosis following implantation of the Absorb Bvs in routine clinical practice: Insight into possible mechanisms from optical coherence tomography

      Objectives To identify potential underlying mechanisms of early and (very) late scaffold thrombosis (ScT) by optical coherence tomography (OCT), in a frame-by-frame analysis. Background The absorb scaffold is associated with an increased risk of ScT compared with metallic stents. Several potential causes of bioresorbable ScT have been identified, however the precise etiology still remains unclear. Methods Between February 2013 and February 2016, 13 patients presenting with definite ScT underwent OCT imaging. After guidewire passage or balloon inflations, OCT images were acquired. Pullbacks were assessed offline at each 1 mm longitudinal interval within the treated segment and the 5 mm segments ...

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      Mentions: Hector M. Garcia-Garcia

    3. Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Explore Circulation Cardiology
      Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography

      Background— The long-term fate of Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, CA) struts jailing side branch ostia has not been clarified. We therefore evaluate serially (post-procedure and at 6 months, 1, 2, 3, and 5 years) the appearance and fate of jailed Absorb bioresorbable vascular scaffold struts. Methods and Results— We performed 3-dimensional optical coherence tomographic analysis of the ABSORB Cohort B trial (A Clinical Evaluation of the Bioabsorbable Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) up to 5 years using a novel, validated cut-plane analysis method. We ...

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      Mentions: Patrick W. Serruys Stephan Windecker Yoshinobu Onuma

    4. Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial

      Explore ResearchGate Cardiology
      Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial

      Aims: The purpose of this study was to assess the vascular response and vessel healing of overlapped Absorb scaffolds (Abbott Vascular, Santa Clara, CA, USA) compared to non-overlapped devices in human coronary arteries as assessed by optical coherence tomography (OCT) in the same treated segment. Methods and results: The ABSORB EXTEND (NCT01023789) trial is a prospective, single-arm, openlabel clinical study which enrolled 800 patients. The planned overlap OCT subgroup in the ABSORB EXTEND trial was analysed and two-year OCT follow-up was performed in seven patients. In cross-section level analysis at baseline, lumen and abluminal scaffold areas were larger in overlap ...

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      Mentions: Imperial College London University of Manchester Patrick W. Serruys

    5. Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?

      Explore eurointervention.org Cardiology
      Is quantitative coronary angiography reliable in assessing the late lumen loss of the everolimus eluting bioresorbable polylactide scaffold in comparison with the cobalt chromium metallic stent?

      Aims: Immediately after stent/scaffold implantation, quantitative coronary angiography (QCA) with respect to optical coherence tomography (OCT) more severely underestimates the lumen diameter (LD) in Absorb than in XIENCE. This OCT-QCA discrepancy has not been evaluated at long-term follow-up. The present study aimed to assess the accuracy of QCA with reference to OCT in Absorb as compared to XIENCE.

       

       

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      Mentions: Beth Israel Deaconess Medical Center Columbia University Leiden University

    6. Evaluation of vascular healing of polymer-free sirolimus-eluting stents in native coronary artery stenosis: a serial follow-up at three and six months with optical coherence tomography imaging

      Explore eurointervention.org Cardiology
      Evaluation of vascular healing of polymer-free sirolimus-eluting stents in native coronary artery stenosis: a serial follow-up at three and six months with optical coherence tomography imaging

      Aims: Our aim was to assess vascular response after polymer-free sirolimus-eluting stent (SES) implantation by using an optical coherence tomography (OCT)-derived vascular healing score (HS), quantifying the deficiency of healing. Methods and results: In a prospective, multicentre, single-arm, open-label study, OCT examinations were performed at three months in 45 patients (47 lesions). Per protocol, 24 lesions which had not reached adequate vascular healing according to study criteria were scheduled for OCT examination at six months. The HS was calculated at two time points. Serial OCT imaging demonstrated that the proportion of covered stent struts increased from a median of ...

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      Mentions: Patrick W. Serruys Hector M. Garcia-Garcia Yoshinobu Onuma

    7. Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography

      Explore Home - Springer Cardiology
      Quantitative assessment of the stent/scaffold strut embedment analysis by optical coherence tomography

      The degree of stent/scaffold embedment could be a surrogate parameter of the vessel wall-stent/scaffold interaction and could have biological implications in the vascular response. We have developed a new specific software for the quantitative evaluation of embedment of struts by optical coherence tomography (OCT). In the present study, we described the algorithm of the embedment analysis and its reproducibility. The degree of embedment was evaluated as the ratio of the embedded part versus the whole strut height and subdivided into quartiles. The agreement and the inter- and intra-observer reproducibility were evaluated using the kappa and the interclass correlation ...

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      Mentions: Imperial College London Leiden University Patrick W. Serruys

    8. Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography

      Explore eurointervention.org Cardiology
      Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography

      Aims: The Tryton bifurcation stent has been developed to improve clinical outcomes after treatment of bifurcation lesions. Limited data are available on the use of the Absorb bioresorbable vascular scaffold (BVS) in bifurcation lesions with side branches >2 mm. We present here the acute procedural results and midterm clinical follow-up of the first-in-man combined use of the Tryton stent and the Absorb scaffold for the treatment of complex bifurcation lesions. Methods and results: Ten patients treated with the Tryton stent in combination with Absorb BVS were included in the current report. Offline two- and three-dimensional optical coherence tomography (OCT) analyses ...

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      Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin

    9. Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study

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      Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study

      The bare-metal Tryton Side Branch (SB) Stent™ (Tryton Medical, Durham, NC, USA) is used with a drug-eluting stent (DES) in the main branch (MB) to treat bifurcation lesions. It is argued that a drug-eluting Tryton-version is needed to improve clinical outcomes, although previous registries have shown good clinical results. More insights in neo-intimal hyperplasia (NIH) growth patterns of the Tryton treatment strategy are needed to decide if and where to drug-coat the stent. Ten patients returned for follow-up angiography (mean follow-up time 393 ± 103 days) and optical coherence tomography (OCT) pullbacks from the MB were obtained in all patients and ...

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      Mentions: National Institutes of Health Academic Medical Center at the University of Amsterdam Hector M. Garcia-Garcia

    10. Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof

      Explore International Journal of Cardiology Cardiology
      Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof

      Previous trials on the ABSORB (Abbott Vascular, Santa Clara, USA) everolimus-eluting bioresorbable vascular scaffold (BVS) were predominated by relatively low-risk lesions, excluding patients with left main coronary artery (LMCA) lesions and bifurcation lesions involving side branches >2mm . Little is known about the safety and feasibility of fenestration and dilation of the side branch ostium after BVS placement .

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      Mentions: Academic Medical Center at the University of Amsterdam Daniël M. de Bruin

    11. Successful treatment of a long tapered lesion with two overlapping ABSORB® bioresorbable vascular scaffolds of different diameters: Evaluation by three-dimensional optical coherence tomography

      Explore International Journal of Cardiology Cardiology
      Successful treatment of a long tapered lesion with two overlapping ABSORB® bioresorbable vascular scaffolds of different diameters: Evaluation by three-dimensional optical coherence tomography

      A 53-year-old male patient with a history of diabetes, hypertension and dyslipidemia presented with stable angina pectoris. Coronary angiography showed a long lesion extending from the proximal to the mid left anterior descending coronary artery (LAD), approximately 40mm in length, with proximal and distal reference diameters of 3.5mm and 2.5mm by visual estimation, and 3.6mm and 2.8mm respectively on online analysis of quantitative coronary angiography. Pre-dilatation with a 2.5×20mm compliant balloon at 10atmospheres (atm) was followed by deployment of two overlapping ABSORB (Abbott Vascular, Santa Clara, USA) bioresorbable vascular scaffolds (BVS). In the mid ...

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      Mentions: Academic Medical Center at the University of Amsterdam Ton G. van Leeuwen Daniël M. de Bruin

    12. Assessment of Coronary Atherosclerosis Progression and Regression at Bifurcations Using Combined IVUS and OCT

      Explore imaging.onlinejacc.org Cardiology
      Assessment of Coronary Atherosclerosis Progression and Regression at Bifurcations Using Combined IVUS and OCT

      Objectives The aim of this study was to evaluate the progression of atherosclerotic coronary plaques at bifurcations, using combined intravascular ultrasound–virtual histology (IVUS-VH) and optical coherence tomography (OCT). Background Pathological findings reveal that atherosclerotic plaques characterized by the presence of large necrotic cores (NCs) with fibrous cap thicknesses < 65 µm are more prone to rupture. Accuracy in the detection of high-risk plaques could be improved by the combined use of IVUS-VH and OCT. Methods IVUS-VH and OCT are 2 imaging modalities with different lateral resolutions and different depths of penetration. To provide a precise matching of the images, bifurcations ...

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      Mentions: Patrick W. Serruys Evelyn Regar Hector M. Garcia-Garcia

    13. Comparison of Acute Vessel Wall Injury After Self-Expanding Stent and Conventional Balloon-Expandable Stent Implantation: A Study with Optical Coherence Tomography

      Explore Invasive Cardiology Cardiology
      Comparison of Acute Vessel Wall Injury After Self-Expanding Stent and Conventional Balloon-Expandable Stent Implantation: A Study with Optical Coherence Tomography
      Background. The acute impact in vivo from a self-expanding stent on the vessel wall has not been sufficiently evaluated. Objectives. We sought to compare acute in vivo injury on the vessel wall and the clinical impact between a self-expanding coronary stent and conventional balloon-expandable stents immediately after stent implantation. Methods. We included 40 patients (45 vessels) with stable or unstable angina who were assigned to either the self-expanding stent (vProtect® Luminal Shield) group (n = 9; Group 1) or the conventional balloon-expandable stent group (n = 36; Group 2). Optical coherence tomography (OCT) was performed after stent deployment, as were qualitative and ...
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      Mentions: Patrick W. Serruys Evelyn Regar Hector M. Garcia-Garcia

    14. 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side Branches by Bioresorbable Vascular Scaffolds: A Proposal for Classification

      Explore interventions.onlinejacc.org Cardiology
      3-Dimensional Optical Coherence Tomography Assessment of Jailed Side Branches by Bioresorbable Vascular Scaffolds: A Proposal for Classification
      Objectives The purpose of this study is to assess jailing of side branches (SB) by the everolimus-eluting, bioresorbable vascular scaffold (BVS) with 3-dimensional (3D) optical coherence tomography (OCT) reconstruction. Background Because BVS struts at the SB orifice are suspected of being bioresorbed and/or forming a neointimal bridge, OCT has been used to evaluate the struts in detail at that particular site. Our understanding of the 3D relationship of the strut and the SB orifice is limited by the use of 2-dimensional OCT images. Fourier-domain OCT enables reliable 3D reconstruction of coronary vessels. Methods The ABSORB Cohort B (A Clinical ...
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      Mentions: Patrick W. Serruys Evelyn Regar Hector M. Garcia-Garcia

    15. Optical coherence tomography for the assessment of pericardium covered stents for the treatment of degenerated saphenous vein grafts

      Explore eurointervention.org Cardiology
      Optical coherence tomography for the assessment of pericardium covered stents for the treatment of degenerated saphenous vein grafts
      Aims: Pre- and post-interventional optical coherence tomography (OCT) assessment of degenerated saphenous vein graphs (SVG) treated with implantation of pericardium covered stents. Percutaneous treatment of SVG represents one of the major challenges of current percutaneous coronary interventions (PCI). Artificial membrane-covered stents have failed to show additional benefit over conventional stents. Conclusion: These case offer insight into the mechanism of protection against distal embolisation, elucidated by the appearance of these stents after deployment in vivo and in vitro.
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      Mentions: Carlo Di Mario Royal Brompton Hospital Lightlab M3 Imaging Console

    16. First case of stenting of a vulnerable plaque in the Secritt I trial—the dawn of a new era?

      Explore Nature Publishing Group Cardiology
      Background. A 63-year-old man presented with class II anginal symptoms. Investigations. Cardiac catheterization, intravascular ultrasound (IVUS) virtual histology, optical coherence tomography and off-line palpography. Diagnosis. The patient was diagnosed as having a culprit lesion in the left circumflex artery and a vulnerable plaque in the left anterior descending artery. Management. The culprit lesion was treated with two overlapping drug-eluting stents. The vulnerable plaque was then treated with a self-expanding stent tailored to shield vulnerable plaques (vProtect® Luminal Shield). After dilatation of the stent with a low-pressure balloon, IVUS and optical coherence tomography showed excellent apposition of the stent to the ...
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      Mentions: Patrick W. Serruys Evelyn Regar Hector M. Garcia-Garcia
    1-16 of 16
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    1. (10 articles) Erasmus University
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    Optical coherence tomography for the assessment of pericardium covered stents for the treatment of degenerated saphenous vein grafts 3-Dimensional Optical Coherence Tomography Assessment of Jailed Side Branches by Bioresorbable Vascular Scaffolds: A Proposal for Classification Comparison of Acute Vessel Wall Injury After Self-Expanding Stent and Conventional Balloon-Expandable Stent Implantation: A Study with Optical Coherence Tomography Assessment of Coronary Atherosclerosis Progression and Regression at Bifurcations Using Combined IVUS and OCT Successful treatment of a long tapered lesion with two overlapping ABSORB® bioresorbable vascular scaffolds of different diameters: Evaluation by three-dimensional optical coherence tomography Three-dimensional optical coherence tomography evaluation of a left main bifurcation lesion treated with ABSORB® bioresorbable vascular scaffold including fenestration and dilatation of the side branch - Corrected Proof Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study Treatment of coronary bifurcation lesions with the Absorb bioresorbable vascular scaffold in combination with the Tryton dedicated coronary bifurcation stent: evaluation using two- and three-dimensional optical coherence tomography Serial 5-Year Evaluation of Side Branches Jailed by Bioresorbable Vascular Scaffolds Using 3-Dimensional Optical Coherence Tomography IMAGING TECHNIQUE FROM BECKMAN LAB NAMED TOP 10 MICROSCOPY INNOVATION Optical coherence refraction tomography University of Southern California Receives NIH Grant for Imaging Cerebral and Retinal Microvasculature in Cerebral Small Vessel Disease