1. Articles from Jack Phu

    1-5 of 5
    1. Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography

      Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography

      Purpose Studies examining the anterior chamber angle and angle closure disease often compare quantitative angle information obtained using anterior segment optical coherence tomography (ASOCT) with one of several ordinal scales derived using gonioscopy. We test the assumption that the ordinal gonioscopic angle grades have equal step sizes and can be analysed using metric statistics. Methods The medical records of 214 consecutive patients who were referred for assessment of the anterior chamber angle were prospectively examined using gonioscopy and ASOCT (Spectralis Optical Coherence Tomography, OCT, www.heidelbergengineering.com ). Anterior chamber angle parameters (angle opening distance, AOD, and trabecular‐iris space area ...

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    2. Remote Grading of the Anterior Chamber Angle Using Goniophotographs and Optical Coherence Tomography: Implications for Telemedicine or Virtual Clinics

      Remote Grading of the Anterior Chamber Angle Using Goniophotographs and Optical Coherence Tomography: Implications for Telemedicine or Virtual Clinics

      Purpose : To evaluate the agreement and accuracy of grading goniophotographs and anterior segment optical coherence tomography (AS-OCT) results for assessment of the anterior chamber angle, and elicit factors driving concordance between perceived grade and ground truth. Methods : Three clinicians evaluated the goniophotographs and AS-OCT results of 75 patients. Graders' impressions of the angle grade, trabecular pigmentation, and iris contour were compared with the ground truth gonioscopic examination result when physically performed by a senior optometrist. Percentage agreement and kappa statistics were calculated. Binary logistic regression was used to elicit factors for accurate grading. Results : Exact angle matches and binary (open ...

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    3. Development of a spatial model of age-related change in the macular ganglion cell layer to predict function from structural changes

      Development of a spatial model of age-related change in the macular ganglion cell layer to predict function from structural changes

      Purpose To develop location specific models of normal, age-related changes in the macular ganglion cell layer (GCL) from optical coherence tomography (OCT). Using these OCT-derived models, we predicted visual field (VF) sensitivity and compared these results to actual VF sensitivities. Design Retrospective cohort study Methods Single eyes of 254 normal participants were retrospectively enrolled from the Centre for Eye Health (Sydney, Australia). Macular GCL measurements were obtained using Spectralis OCT. Cluster algorithms were performed to identify spatial patterns demonstrating similar age-related change. Quadratic and linear regression models were subsequently utilized to characterize age-related GCL decline. 40 participants underwent additional testing ...

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    4. An evidence-based approach to the routine use of optical coherence tomography

      An evidence-based approach to the routine use of optical coherence tomography

      Optical coherence tomography is an imaging technology that has revolutionised the detection, assessment and management of ocular disease. It is now a mainstream technology in clinical practice and is performed by non-specialised personnel in some settings. This article provides a clinical perspective on the implications of that movement and describes best practice using multimodal imaging and an evidence-based approach. Practical, illustrative guides on the interpretation of optical coherence tomography are provided for three major diseases of the ocular fundus, in which optical coherence tomography is often crucial to management: age-related macular degeneration, diabetic retinopathy and glaucoma. Topics discussed include: cross-sectional ...

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    5. An evidence‐based approach to the routine use of optical coherence tomography

      An evidence‐based approach to the routine use of optical coherence tomography

      Optical coherence tomography is an imaging technology that has revolutionised the detection, assessment and management of ocular disease. It is now a mainstream technology in clinical practice and is performed by non‐specialised personnel in some settings. This article provides a clinical perspective on the implications of that movement and describes best practice using multimodal imaging and an evidence‐based approach. Practical, illustrative guides on the interpretation of optical coherence tomography are provided for three major diseases of the ocular fundus, in which optical coherence tomography is often crucial to management: age‐related macular degeneration, diabetic retinopathy and glaucoma. Topics ...

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    1-5 of 5
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    1. (3 articles) University of New South Wales
    2. (1 articles) Heidelberg Engineering
    3. (1 articles) Carl Zeiss Meditec
    4. (1 articles) Optos
    5. (1 articles) University of Washington
    6. (1 articles) University of Melbourne
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    An evidence‐based approach to the routine use of optical coherence tomography An evidence-based approach to the routine use of optical coherence tomography Development of a spatial model of age-related change in the macular ganglion cell layer to predict function from structural changes Remote Grading of the Anterior Chamber Angle Using Goniophotographs and Optical Coherence Tomography: Implications for Telemedicine or Virtual Clinics Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography Carotid Disease and Retinal Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes: The Fremantle Diabetes Study Phase II Retinal Vascular Density on Optical Coherence Tomography Angiography and Age-related Central and Peripheral Hearing Loss in a Southern Italian Older Population Optical coherence tomography outcomes from SPRINT-MS, a multicenter, randomized, double-blind trial of ibudilast in progressive multiple sclerosis Microvascular alterations in children with optic disk drusen evaluated by optical coherence tomography angiography Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis